An Integrative Synthetic Biology Approach to Interrogating Cellular Ubiquitin and Ufm Signaling

Recent insight into the role of FBXW7 as a tumor suppressor

(2020) Kanae Yumimoto et al.   SEMINARS IN CANCER BIOLOGY

Ribosomal protein RPL26 is the principal target of UFMylation

(2019) Christopher P. Walczak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

UBE3A: An E3 Ubiquitin Ligase With Genome-Wide Impact in Neurodevelopmental Disease

(2019) Simon Jesse Lopez et al.   Frontiers in Molecular Neuroscience

UFL1 promotes histone H4 ufmylation and ATM activation

(2019) Bo Qin et al.   Nature Communications

UBE3A regulates the transcription of IRF, an antiviral immunity

(2019) Ryohei Furumai et al.   HUMAN MOLECULAR GENETICS

Impaired neurodevelopmental pathways in autism spectrum disorder: a review of signaling mechanisms and crosstalk

(2019) Santosh Kumar et al.   Journal of Neurodevelopmental Disorders

The N-Degron Pathway Mediates ER-phagy

(2019) Chang Hoon Ji et al.   MOLECULAR CELL

Recent trends of capillary electrophoresis‐mass spectrometry in proteomics research

(2019) Fabio P. Gomes et al.   MASS SPECTROMETRY REVIEWS

Insights into ubiquitin chain architecture using Ub-clipping

(2019) Kirby N. Swatek et al.   NATURE

Enzymatic Logic of Ubiquitin Chain Assembly

(2019) Kirandeep K. Deol et al.   Frontiers in Physiology

UFMylation of RPL26 links translocation-associated quality control to endoplasmic reticulum protein homeostasis

(2019) Lihui Wang et al.   CELL RESEARCH

Imprinting effects of UBE3A loss on synaptic gene networks and Wnt signaling pathways

(2019) S Jesse Lopez et al.   HUMAN MOLECULAR GENETICS

Cellular quality control by the ubiquitin-proteasome system and autophagy

(2019) Christian Pohl et al.   SCIENCE

The ever expanding scope of electrospray mass spectrometry—a 30 year journey

(2019) Matthias Mann   Nature Communications

Biallelic UFM1 and UFC1 mutations expand the essential role of ufmylation in brain development

(2018) Michael S Nahorski et al.   BRAIN

Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer

(2018) Karan Bhuripanyo et al.   Science Advances

Autophagy in the liver: functions in health and disease

(2017) Takashi Ueno et al.   Nature Reviews Gastroenterology & Hepatology

The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy

(2017) Yong Tae Kwon et al.   TRENDS IN BIOCHEMICAL SCIENCES

A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability

(2017) Jiang Liu et al.   Nature Communications

Systematic approaches to identify E3 ligase substrates

(2016) M. Iconomou et al.   BIOCHEMICAL JOURNAL

Recent progress in ubiquitin and ubiquitin-like protein (Ubl) signaling

(2016) Ronggui Hu et al.   CELL RESEARCH

E2 enzymes: more than just middle men

(2016) Mikaela D Stewart et al.   CELL RESEARCH

The increasing complexity of the ubiquitin code

(2016) Richard Yau et al.   NATURE CELL BIOLOGY

A bacterial genetic selection system for ubiquitylation cascade discovery

(2016) Olga Levin-Kravets et al.   NATURE METHODS

Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62

(2016) Rowena DeJesus et al.   eLife

Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes

(2016) Christopher M. Rose et al.   Cell Systems

Mechanisms of retinoic acid signalling and its roles in organ and limb development

(2015) Thomas J. Cunningham et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

From UBE3A to Angelman syndrome: a substrate perspective

(2015) Gabrielle L. Sell et al.   Frontiers in Neuroscience

Ubiquitylation of Autophagy Receptor Optineurin by HACE1 Activates Selective Autophagy for Tumor Suppression

(2014) Zhengzhao Liu et al.   CANCER CELL

Autoregulation of the 26S proteasome by in situ ubiquitination

(2014) Andrew D. Jacobson et al.   MOLECULAR BIOLOGY OF THE CELL

Modification of ASC1 by UFM1 Is Crucial for ERα Transactivation and Breast Cancer Development

(2014) Hee Min Yoo et al.   MOLECULAR CELL

Ubiquitin Ligase Trapping Identifies an SCFSaf1 Pathway Targeting Unprocessed Vacuolar/Lysosomal Proteins

(2014) Kevin G. Mark et al.   MOLECULAR CELL

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

When ubiquitination meets phosphorylation: a systems biology perspective of EGFR/MAPK signalling

(2013) Lan K Nguyen et al.   Cell Communication and Signaling

Metallothionein MT1M is a tumor suppressor of human hepatocellular carcinomas

(2012) Jun Mao et al.   CARCINOGENESIS

Synthetic biology approach to reconstituting the ubiquitylation cascade in bacteria

(2011) Tal Keren-Kaplan et al.   EMBO JOURNAL

Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways

(2011) T.-F. Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Novel Type of E3 Ligase for the Ufm1 Conjugation System

(2009) Kanako Tatsumi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Label-free Quantitative Proteomics Strategy to Identify E3 Ubiquitin Ligase Substrates Targeted to Proteasome Degradation

(2009) Clara F. Burande et al.   MOLECULAR & CELLULAR PROTEOMICS

Origin and function of ubiquitin-like proteins

(2009) Mark Hochstrasser   NATURE

Characterization of Polyubiquitin Chain Structure by Middle-down Mass Spectrometry

(2008) Ping Xu et al.   ANALYTICAL CHEMISTRY