UBE3A regulates the transcription of IRF, an antiviral immunity

CNV biology in neurodevelopmental disorders

(2018) Toru Takumi et al.   CURRENT OPINION IN NEUROBIOLOGY

Network Analysis of UBE3A/E6AP-Associated Proteins Provides Connections to Several Distinct Cellular Processes

(2018) Gustavo Martínez-Noël et al.   JOURNAL OF MOLECULAR BIOLOGY

Neuronal overexpression of Ube3a isoform 2 causes behavioral impairments and neuroanatomical pathology relevant to 15q11.2-q13.3 duplication syndrome

(2017) Nycole A Copping et al.   HUMAN MOLECULAR GENETICS

Autism gene Ube3a and seizures impair sociability by repressing VTA Cbln1

(2017) Vaishnav Krishnan et al.   NATURE

Subcellular organization of UBE3A in neurons

(2016) Alain C. Burette et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Angelman syndrome — insights into a rare neurogenetic disorder

(2016) Karin Buiting et al.   Nature Reviews Neurology

Maternal immune activation: Implications for neuropsychiatric disorders

(2016) M. L. Estes et al.   SCIENCE

An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A

(2015) Jason J. Yi et al.   CELL

Model mice for 15q11–13 duplication syndrome exhibit late-onset obesity and altered lipid metabolism

(2015) Rui Kishimoto et al.   HUMAN MOLECULAR GENETICS

Ube3a reinstatement identifies distinct developmental windows in a murine Angelman syndrome model

(2015) Sara Silva-Santos et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammatory Cytokines: Potential Biomarkers of Immunologic Dysfunction in Autism Spectrum Disorders

(2015) Ningan Xu et al.   MEDIATORS OF INFLAMMATION

A coding-independent function of an alternative Ube3a transcript during neuronal development

(2015) Jeremy Valluy et al.   NATURE NEUROSCIENCE

UBE3A Regulates Synaptic Plasticity and Learning and Memory by Controlling SK2 Channel Endocytosis

(2015) Jiandong Sun et al.   Cell Reports

An open-label pilot trial of minocycline in children as a treatment for Angelman syndrome

(2014) Joseph C Grieco et al.   BMC Neurology

IRF4 is a novel mediator for neuronal survival in ischaemic stroke

(2014) S Guo et al.   CELL DEATH AND DIFFERENTIATION

Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production

(2014) Yan Li et al.   GENES & DEVELOPMENT

IRF8 is a transcriptional determinant for microglial motility

(2014) Takahiro Masuda et al.   Purinergic Signalling

Transcription factor IRF5 drives P2X4R+-reactive microglia gating neuropathic pain

(2014) Takahiro Masuda et al.   Nature Communications

Minocycline: far beyond an antibiotic

(2013) N Garrido-Mesa et al.   BRITISH JOURNAL OF PHARMACOLOGY

Allelic specificity of Ube3a Expression In The Mouse Brain During Postnatal Development

(2013) Matthew C. Judson et al.   JOURNAL OF COMPARATIVE NEUROLOGY

The Angelman Syndrome Protein Ube3a Is Required for Polarized Dendrite Morphogenesis in Pyramidal Neurons

(2013) S. Miao et al.   JOURNAL OF NEUROSCIENCE

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

(2013) Katrin Kierdorf et al.   NATURE NEUROSCIENCE

Role of the ubiquitin ligase E6AP/UBE3A in controlling levels of the synaptic protein Arc

(2013) S. Kuhnle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Transcription Factors for Lineage-Specific ESC Differentiation

(2013) Kohei Yamamizu et al.   Stem Cell Reports

Defective glucocorticoid hormone receptor signaling leads to increased stress and anxiety in a mouse model of Angelman syndrome

(2012) Swetha K. Godavarthi et al.   HUMAN MOLECULAR GENETICS

Dysfunction of the Ubiquitin Ligase Ube3a May Be Associated with Synaptic Pathophysiology in a Mouse Model of Huntington Disease

(2012) Megha Maheshwari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ERα Phosphorylation at Y537 by Src Triggers E6-AP-ERα Binding, ERα Ubiquitylation, Promoter Occupancy, and Target Gene Expression

(2012) Jun Sun et al.   MOLECULAR ENDOCRINOLOGY

IFN Regulatory Factor 8 Is a Key Constitutive Determinant of the Morphological and Molecular Properties of Microglia in the CNS

(2012) Carsten Minten et al.   PLoS One

Decreased Tonic Inhibition in Cerebellar Granule Cells Causes Motor Dysfunction in a Mouse Model of Angelman Syndrome

(2012) K. Egawa et al.   Science Translational Medicine

IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive Phenotype

(2012) Takahiro Masuda et al.   Cell Reports

The neurobiology of mouse models syntenic to human chromosome 15q

(2011) Toru Takumi   Journal of Neurodevelopmental Disorders

A Novel Transcription Complex That Selectively Modulates Apoptosis of Breast Cancer Cells through Regulation of FASTKD2

(2011) K. T. Yeung et al.   MOLECULAR AND CELLULAR BIOLOGY

Interferon Regulatory Factor 2 Binding Protein 2 Is a New NFAT1 Partner and Represses Its Transcriptional Activity

(2011) F. R. G. Carneiro et al.   MOLECULAR AND CELLULAR BIOLOGY

Increased Gene Dosage of Ube3a Results in Autism Traits and Decreased Glutamate Synaptic Transmission in Mice

(2011) S. E. P. Smith et al.   Science Translational Medicine

Angelman syndrome: insights into genomic imprinting and neurodevelopmental phenotypes

(2011) Angela M. Mabb et al.   TRENDS IN NEUROSCIENCES

Open-label add-on treatment trial of minocycline in fragile X syndrome

(2010) Carlo Paribello et al.   BMC Neurology

EphB-Mediated Degradation of the RhoA GEF Ephexin5 Relieves a Developmental Brake on Excitatory Synapse Formation

(2010) Seth S. Margolis et al.   CELL

The Angelman Syndrome Protein Ube3A Regulates Synapse Development by Ubiquitinating Arc

(2010) Paul L. Greer et al.   CELL

Genome-wide gene expression profiling of the Angelman syndrome mice with Ube3a mutation

(2010) Daren Low et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Tissue-specific variation of Ube3a protein expression in rodents and in a mouse model of Angelman syndrome

(2010) Richard M. Gustin et al.   NEUROBIOLOGY OF DISEASE

Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon–dependent exhaustion

(2009) Taku Sato et al.   NATURE MEDICINE

Association of Family History of Autoimmune Diseases and Autism Spectrum Disorders

(2009) H. O. Atladottir et al.   PEDIATRICS

Role of Mdm2 acid domain interactions in recognition and ubiquitination of the transcription factor IRF-2

(2008) Susanne Pettersson et al.   BIOCHEMICAL JOURNAL

IRF2-binding protein-1 is a JDP2 ubiquitin ligase and an inhibitor of ATF2-dependent transcription

(2008) Makoto Kimura   FEBS LETTERS

The novel p53 target gene IRF2BP2 participates in cell survival during the p53 stress response

(2008) Max Koeppel et al.   NUCLEIC ACIDS RESEARCH