Anti-COVID drugs: repurposing existing drugs or search for new complex entities, strategies and perspectives

Can Chinese Medicine Be Used for Prevention of Corona Virus Disease 2019 (COVID-19)? A Review of Historical Classics, Research Evidence and Current Prevention Programs

(2020) Hui Luo et al.   Chinese Journal of Integrative Medicine

Discovery and development of safe-in-man broad-spectrum antiviral agents

(2020) Petter I. Andersen et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak

(2020) Hussin A. Rothan et al.   JOURNAL OF AUTOIMMUNITY

Therapeutic options for the 2019 novel coronavirus (2019-nCoV)

(2020) Guangdi Li et al.   NATURE REVIEWS DRUG DISCOVERY

Traditional Chinese and Western Medicines Jointly Beat COVID-19 Pandemic

(2020) Guang-chao Qing et al.   Chinese Journal of Integrative Medicine

COVID-19 pandemic and the skin: what should dermatologists know?

(2020) Razvigor Darlenski et al.   CLINICS IN DERMATOLOGY

Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study

(2020) Jerome R. Lechien et al.   EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY

Ligand‐centered assessment of SARS‐CoV‐2 drug target models in the Protein Data Bank

(2020) Alexander Wlodawer et al.   FEBS Journal

Structural and Evolutionary Analysis Indicate That the SARS-CoV-2 Mpro Is a Challenging Target for Small-Molecule Inhibitor Design

(2020) Maria Bzówka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Identification of phytochemical inhibitors against main protease of COVID-19 using molecular modeling approaches

(2020) Anuj Kumar et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant

(2020) Maria Pachetti et al.   Journal of Translational Medicine

COVID-19-associated nephritis: early warning for disease severity and complications?

(2020) Oliver Gross et al.   LANCET

Smell and taste dysfunction in patients with COVID-19

(2020) Michael S Xydakis et al.   LANCET INFECTIOUS DISEASES

Pharmacological (or Synthetic) and Nutritional Agonists of PPAR-γ as Candidates for Cytokine Storm Modulation in COVID-19 Disease

(2020) Carmen Ciavarella et al.   MOLECULES

COVID-19, Chloroquine Repurposing, and Cardiac Safety Concern: Chirality Might Help

(2020) Giovanni Lentini et al.   MOLECULES

Virtual Screening of Natural Products against Type II Transmembrane Serine Protease (TMPRSS2), the Priming Agent of Coronavirus 2 (SARS-CoV-2)

(2020) Noor Rahman et al.   MOLECULES

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors

(2020) Zhenming Jin et al.   NATURE

Rapid repurposing of drugs for COVID-19

(2020) R. Kiplin Guy et al.   SCIENCE

SARS-CoV-2/COVID-19: Viral Genomics, Epidemiology, Vaccines, and Therapeutic Interventions

(2020) Mohammed Uddin et al.   Viruses-Basel

A Novel Combination of Vitamin C, Curcumin and Glycyrrhizic Acid Potentially Regulates Immune and Inflammatory Response Associated with Coronavirus Infections: A Perspective from System Biology Analysis

(2020) Liang Chen et al.   Nutrients

Coronavirus Diseases (COVID-19) Current Status and Future Perspectives: A Narrative Review

(2020) Francesco Di Gennaro et al.   International Journal of Environmental Research and Public Health

SARS-CoV-2 (COVID-19): New Discoveries and Current Challenges

(2020) Ghazaleh Jamalipour Soufi et al.   Applied Sciences-Basel

Synthesis and anti-hepaticfibrosis of glycyrrhetinic acid derivatives with inhibiting COX-2

(2020) Qiuping Zhang et al.   BIOORGANIC CHEMISTRY

COVID19 inhibitors: A prospective therapeutics

(2020) Md Jawaid Akhtar   BIOORGANIC CHEMISTRY

Nrf2 Activator PB125® as a Potential Therapeutic Agent against COVID-19

(2020) Joe M. McCord et al.   Antioxidants

The Rationale for Potential Pharmacotherapy of COVID-19

(2020) Maha Saber-Ayad et al.   Pharmaceuticals

Fight against novel coronavirus: A perspective of medicinal chemists

(2020) Sk Abdul Amin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Recent Developments in the Functionalization of Betulinic Acid and Its Natural Analogues: A Route to New Bioactive Compounds

(2019) Joana L. C. Sousa et al.   MOLECULES

Triterpene-Based Carboxamides Act as Good Inhibitors of Butyrylcholinesterase

(2019) Anne Loesche et al.   MOLECULES

Morpholide derivative of the novel oleanolic oxime and succinic acid conjugate diminish the expression and activity of NF-κB and STATs in human hepatocellular carcinoma cells

(2019) Violetta Krajka-Kuźniak et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Oleanolic acid oxime derivatives and their conjugates with aspirin modulate the NF-κB-mediated transcription in HepG2 hepatoma cells

(2019) Violetta Krajka-Kuźniak et al.   BIOORGANIC CHEMISTRY

Molecular Consortia—Various Structural and Synthetic Concepts for More Effective Therapeutics Synthesis

(2018) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antiviral Activities of Oleanolic Acid and Its Analogues

(2018) Vuyolwethu Khwaza et al.   MOLECULES

Synthesis and proapoptotic activity of oleanolic acid derived amides

(2016) Lucie Heller et al.   BIOORGANIC CHEMISTRY

Hybrid Compounds Strategy in the Synthesis of Oleanolic Acid Skeleton-NSAID Derivatives

(2016) Anna Pawełczyk et al.   MOLECULES

Synthesis and cytotoxic evaluation of several oleanolic acid–uracil/thymine conjugates

(2016) Ke-Guang Cheng et al.   MedChemComm

Strong and Long-Lasting Antinociceptive and Anti-inflammatory Conjugate of Naturally Occurring Oleanolic Acid and Aspirin

(2016) Barbara Bednarczyk-Cwynar et al.   Frontiers in Pharmacology

Synthesis of triterpenoid acylates: Effective reproduction inhibitors of influenza A (H1N1) and papilloma viruses

(2010) O. B. Kazakova et al.   RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY