Synthesis and cytotoxic evaluation of several oleanolic acid–uracil/thymine conjugates

In search of uracil derivatives as bioactive agents. Uracils and fused uracils: Synthesis, biological activity and applications

(2015) Aleksandra Pałasz et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Metallocene-uracil conjugates: Synthesis and biological evaluation of novel mono-, di- and tri-nuclear systems

(2015) Joanna Skiba et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

One-pot click synthesis of 1,2,3-triazole-embedded unsaturated uracil derivatives and hybrids of 1,5- and 2,5-disubstituted tetrazoles and pyrimidines

(2015) Svjetlana Krištafor et al.   TETRAHEDRON LETTERS

Protection against phalloidin-induced liver injury by oleanolic acid involves Nrf2 activation and suppression of Oatp1b2

(2015) Yuan-Fu Lu et al.   TOXICOLOGY LETTERS

Synthesis of novel conjugates of a saccharide, amino acids, nucleobase and the evaluation of their cell compatibility

(2014) Dan Yuan et al.   Beilstein Journal of Organic Chemistry

Synthesis and cytotoxic evaluation of novel ester-triazole-linked triterpenoid–AZT conjugates

(2014) Tuyet Anh Dang Thi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Oleanolic acid and its synthetic derivatives for the prevention and therapy of cancer: Preclinical and clinical evidence

(2014) Muthu K. Shanmugam et al.   CANCER LETTERS

Synthesis of novel ring-A fused hybrids of oleanolic acid with capabilities to arrest cell cycle and induce apoptosis in breast cancer cells

(2014) Uppuluri Venkata Mallavadhani et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

3-O-[N-(p-fluorobenzenesulfonyl)-carbamoyl]-oleanolic acid, a semisynthetic analog of oleanolic acid, induces apoptosis in breast cancer cells

(2014) Mohamed R. Akl et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Amino Acid Derivatives of Ligustrazine-Oleanolic Acid as New Cytotoxic Agents

(2014) Fuhao Chu et al.   MOLECULES

Synthesis and evaluation of the anticancer activity of albiziabioside A and its analogues as apoptosis inducers against human melanoma cells

(2014) Gaofei Wei et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and biological evaluation of T-OA analogues as the cytotoxic agents

(2014) Kuo Xu et al.   RESEARCH ON CHEMICAL INTERMEDIATES

Methyl 3-hydroxyimino-11-oxoolean-12-en-28-oate (HIMOXOL), a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MDA-MB-231 breast cancer cells

(2013) Natalia Lisiak et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Novel oleanolic vinyl boronates: Synthesis and antitumor activity

(2013) Vânia M. Moreira et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antitumor activities of naturally occurring oleanolic acid triterpenoid saponins and their derivatives

(2013) Qingchao Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, antitumor and antibacterial activities of some novel tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives

(2013) Safinaz E. Abbas et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of oleanolic acid derivatives as PTP1B inhibitors

(2013) Qing-Chao Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and cytotoxic activity of novel 2,6-disubstituted-4-mor-pholinothieno[3,2-d]pyrimidines as potent anti-tumor agents

(2012) Wu Fu Zhu et al.   CHINESE CHEMICAL LETTERS

Oleanolic acid

(2012) Jacob Pollier et al.   PHYTOCHEMISTRY

Supramolecular hydrogels formed by the conjugates of nucleobases, Arg-Gly-Asp (RGD) peptides, and glucosamine

(2012) Xinming Li et al.   Soft Matter

Hybrid Molecules Incorporating Natural Products: Applications in Cancer Therapy, Neurodegenerative Disorders and Beyond

(2011) M. Decker   CURRENT MEDICINAL CHEMISTRY

Triterpenoids for Cancer Prevention and Treatment: Current Status and Future Prospects

(2011) Jagan M.R. Patlolla et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Curcumin induced HepG2 cell apoptosis-associated mitochondrial membrane potential and intracellular free Ca2+ concentration

(2010) Mu Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Synthesis of glucoconjugates of oleanolic acid as inhibitors of glycogen phosphorylase

(2009) Keguang Cheng et al.   CARBOHYDRATE RESEARCH

Anti-AIDS Agents. 78.†Design, Synthesis, Metabolic Stability Assessment, and Antiviral Evaluation of Novel Betulinic Acid Derivatives as Potent Anti-Human Immunodeficiency Virus (HIV) Agents

(2009) Keduo Qian et al.   JOURNAL OF MEDICINAL CHEMISTRY

Naturally Occurring Pentacyclic Triterpenes as Inhibitors of Glycogen Phosphorylase: Synthesis, Structure−Activity Relationships, and X-ray Crystallographic Studies†

(2008) Xiaoan Wen et al.   JOURNAL OF MEDICINAL CHEMISTRY