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Title
How does fascin promote cancer metastasis?
Authors
Keywords
-
Journal
FEBS Journal
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2020-07-13
DOI
10.1111/febs.15484
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Note: Only part of the references are listed.- New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells
- (2020) Begoña Alburquerque-González et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Novel anti-invasive properties of a Fascin1 inhibitor on colorectal cancer cells
- (2020) Silvia Montoro-García et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- LIMS1 Promotes Pancreatic Cancer Cell Survival Under Oxygen-Glucose Deprivation Conditions by Enhancing HIF1A Protein Translation
- (2019) Chongbiao Huang et al. CLINICAL CANCER RESEARCH
- Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents
- (2019) Stuart Francis et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Inflammation and Cancer: Triggers, Mechanisms, and Consequences
- (2019) Florian R. Greten et al. IMMUNITY
- Mass spectrometry‐based proteomic analysis of FSCN1‐interacting proteins in laryngeal squamous cell carcinoma cells
- (2019) Hongliang Liu et al. IUBMB LIFE
- Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments
- (2019) Shengchen Lin et al. Cell Reports
- The mitochondrial deoxyguanosine kinase is required for cancer cell stemness in lung adenocarcinoma
- (2019) Shengchen Lin et al. EMBO Molecular Medicine
- SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair
- (2019) Qi Miao et al. Nature Communications
- TGF-β1 induced fascin1 expression facilitates the migration and invasion of kidney carcinoma cells through ERK and JNK signaling pathways
- (2018) Jianyu Yang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Unique Metabolic Adaptations Dictate Distal Organ-Specific Metastatic Colonization
- (2018) Tanya Schild et al. CANCER CELL
- Fascin induces melanoma tumorigenesis and stemness through regulating the Hippo pathway
- (2018) Jiaxin Kang et al. Cell Communication and Signaling
- FSCN1 Promotes Epithelial-Mesenchymal Transition Through Increasing Snail1 in Ovarian Cancer Cells
- (2018) Jie Li et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Cortactin and fascin-1 regulate extracellular vesicle release by controlling endosomal trafficking or invadopodia formation and function
- (2018) Els Beghein et al. Scientific Reports
- Strong fascin expression promotes metastasis independent of its F-actin bundling activity
- (2017) Lisa S. Heinz et al. Oncotarget
- Control of nuclear organization by F-actin binding proteins
- (2017) Karin Pfisterer et al. Nucleus
- Control of nuclear organization by F-actin binding proteins
- (2017) Karin Pfisterer et al. Nucleus
- Hallmarks of cancer stem cell metabolism
- (2016) Patricia Sancho et al. BRITISH JOURNAL OF CANCER
- Filopodia formation by crosslinking of F-actin with fascin in two different binding manners
- (2016) Shinji Aramaki et al. Cytoskeleton
- Fascin Regulates Nuclear Movement and Deformation in Migrating Cells
- (2016) Asier Jayo et al. DEVELOPMENTAL CELL
- Monoubiquitination Inhibits the Actin Bundling Activity of Fascin
- (2016) Shengchen Lin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fascin Rigidity and L-plastin Flexibility Cooperate in Cancer Cell Invadopodia and Filopodia
- (2016) Isabel Van Audenhove et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Improving fascin inhibitors to block tumor cell migration and metastasis
- (2016) Shaoqin Han et al. Molecular Oncology
- Metastatic colonization by circulating tumour cells
- (2016) Joan Massagué et al. NATURE
- TGF-β1 promotes the migration and invasion of bladder carcinoma cells by increasing fascin1 expression
- (2016) Naiwen Zhang et al. ONCOLOGY REPORTS
- MYC-nick promotes cell migration by inducing fascin expression and Cdc42 activation
- (2016) Sarah Anderson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells
- (2016) Samantha C. Lewis et al. SCIENCE
- Fascin Is Critical for the Maintenance of Breast Cancer Stem Cell Pool Predominantly via the Activation of the Notch Self-Renewal Pathway
- (2016) Rayanah Barnawi et al. STEM CELLS
- Fascin 1 promoted the growth and migration of non-small cell lung cancer cells by activating YAP/TEAD signaling
- (2016) Zhigang Liang et al. TUMOR BIOLOGY
- Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation
- (2016) Zhaoting Liu et al. Nature Communications
- The Tax-Inducible Actin-Bundling Protein Fascin Is Crucial for Release and Cell-to-Cell Transmission of Human T-Cell Leukemia Virus Type 1 (HTLV-1)
- (2016) Christine Gross et al. PLoS Pathogens
- Fascin actin bundling controls podosome turnover and disassembly while cortactin is involved in podosome assembly by its SH3 domain in THP-1 macrophages and dendritic cells
- (2015) Isabel Van Audenhove et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Cancer statistics, 2015
- (2015) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells
- (2015) Patricia Sancho et al. Cell Metabolism
- Accessorizing and anchoring the LINC complex for multifunctionality
- (2015) Wakam Chang et al. JOURNAL OF CELL BIOLOGY
- Fascin expression is increased in metastatic lesions but does not correlate with progression nor outcome in melanoma
- (2015) Yafeng Ma et al. MELANOMA RESEARCH
- Prostaglandins regulate nuclear localization of Fascin and its function in nucleolar architecture
- (2015) Christopher M. Groen et al. MOLECULAR BIOLOGY OF THE CELL
- Regulation of the tumor marker Fascin by the viral oncoprotein Tax of human T-cell leukemia virus type 1 (HTLV-1) depends on promoter activation and on a promoter-independent mechanism
- (2015) Caroline F. Mohr et al. VIROLOGY
- Targeted inhibition of fascin function blocks tumour invasion and metastatic colonization
- (2015) Fang-Ke Huang et al. Nature Communications
- Fascin is involved in the chemotherapeutic resistance of breast cancer cells predominantly via the PI3K/Akt pathway
- (2014) H Ghebeh et al. BRITISH JOURNAL OF CANCER
- MicroRNA-145 inhibits tumour growth and metastasis in colorectal cancer by targeting fascin-1
- (2014) Y Feng et al. BRITISH JOURNAL OF CANCER
- Hypoxia-Inducible Factor-1 Promotes Pancreatic Ductal Adenocarcinoma Invasion and Metastasis by Activating Transcription of the Actin-Bundling Protein Fascin
- (2014) X. Zhao et al. CANCER RESEARCH
- Fascin Plays a Role in Stress Fiber Organization and Focal Adhesion Disassembly
- (2014) Nadia Elkhatib et al. CURRENT BIOLOGY
- A Role for Myosin II in Mammalian Mitochondrial Fission
- (2014) Farida Korobova et al. CURRENT BIOLOGY
- Fascin Is Regulated by Slug, Promotes Progression of Pancreatic Cancer in Mice, and Is Associated With Patient Outcomes
- (2014) Ang Li et al. GASTROENTEROLOGY
- Stress-induced cleavage of Myc promotes cancer cell survival
- (2014) M. Conacci-Sorrell et al. GENES & DEVELOPMENT
- Mitochondrial form and function
- (2014) Jonathan R. Friedman et al. NATURE
- PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis
- (2014) Valerie S. LeBleu et al. NATURE CELL BIOLOGY
- Fascin regulates chronic inflammation-related human colon carcinogenesis by inhibiting cell anoikis
- (2014) Yusuke Kanda et al. PROTEOMICS
- MicroRNA-133a regulates the mRNAs of two invadopodia-related proteins, FSCN1 and MMP14, in esophageal cancer
- (2013) N Akanuma et al. BRITISH JOURNAL OF CANCER
- GATA3 Transcription Factor Abrogates Smad4 Transcription Factor-mediated Fascin Overexpression, Invadopodium Formation, and Breast Cancer Cell Invasion
- (2013) Jianwei Sun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force
- (2013) Katarina Wolf et al. JOURNAL OF CELL BIOLOGY
- An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2
- (2013) F. Korobova et al. SCIENCE
- Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells
- (2012) M. Janiszewska et al. GENES & DEVELOPMENT
- Expression profiling shows differential molecular pathways and provides potential new diagnostic biomarkers for colorectal serrated adenocarcinoma
- (2012) Pablo Conesa-Zamora et al. INTERNATIONAL JOURNAL OF CANCER
- Molecular Mechanism of Fascin Function in Filopodial Formation
- (2012) Shengyu Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fascin promotes filopodia formation independent of its role in actin bundling
- (2012) Jennifer Zanet et al. JOURNAL OF CELL BIOLOGY
- The Cluster of miR-143 and miR-145 Affects the Risk for Esophageal Squamous Cell Carcinoma through Co-Regulating Fascin Homolog 1
- (2012) Ran Liu et al. PLoS One
- Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
- (2012) Gregg L. Semenza TRENDS IN PHARMACOLOGICAL SCIENCES
- The tumor marker Fascin is strongly induced by the Tax oncoprotein of HTLV-1 through NF- B signals
- (2011) A. K. Kress et al. BLOOD
- The actin-bundling protein Fascin is overexpressed in inflammatory bowel disease and may be important in tissue repair
- (2011) David Qualtrough et al. BMC GASTROENTEROLOGY
- Proinvasion Metastasis Drivers in Early-Stage Melanoma Are Oncogenes
- (2011) Kenneth L. Scott et al. CANCER CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Mitochondrial and energy metabolism-related properties as novel indicators of lung cancer stem cells
- (2011) Xiao-Qun Ye et al. INTERNATIONAL JOURNAL OF CANCER
- Signal Transducers and Activators of Transcription 3 (STAT3) Directly Regulates Cytokine-induced Fascin Expression and Is Required for Breast Cancer Cell Migration
- (2011) Marylynn Snyder et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanism of Actin Filament Bundling by Fascin
- (2011) Silvia Jansen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fascin Protein Is Critical for Transforming Growth Factor β Protein-induced Invasion and Filopodia Formation in Spindle-shaped Tumor Cells
- (2011) Jianwei Sun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function
- (2011) Danielle A. Murphy et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Fascin Is a Key Regulator of Breast Cancer Invasion That Acts via the Modification of Metastasis-Associated Molecules
- (2011) Monther Al-Alwan et al. PLoS One
- A Perspective on Cancer Cell Metastasis
- (2011) C. L. Chaffer et al. SCIENCE
- Specificity protein 1 regulates fascin expression in esophageal squamous cell carcinoma as the result of the epidermal growth factor/extracellular signal-regulated kinase signaling pathway activation
- (2010) Xiao-Feng Lu et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The Actin-Bundling Protein Fascin Stabilizes Actin in Invadopodia and Potentiates Protrusive Invasion
- (2010) Ang Li et al. CURRENT BIOLOGY
- Cancer Dissemination—Lessons from Leukocytes
- (2010) Chris D. Madsen et al. DEVELOPMENTAL CELL
- Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia
- (2010) Marie Schoumacher et al. JOURNAL OF CELL BIOLOGY
- MicroRNA control of podosome formation in vascular smooth muscle cells in vivo and in vitro
- (2010) Manuela Quintavalle et al. JOURNAL OF CELL BIOLOGY
- Is fascin really a useful marker in distinguishing between classical Hodgkin's lymphoma and various types of Non-Hodgkin's lymphomas in difficult cases?
- (2010) R. Idrees et al. JOURNAL OF CLINICAL PATHOLOGY
- Structure, Evolutionary Conservation, and Conformational Dynamics of Homo sapiens Fascin-1, an F-actin Crosslinking Protein
- (2010) Reza Sharifi Sedeh et al. JOURNAL OF MOLECULAR BIOLOGY
- Migrastatin analogues target fascin to block tumour metastasis
- (2010) Lin Chen et al. NATURE
- Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis
- (2010) Junjun Chen et al. Nature Chemical Biology
- miR-145-dependent targeting of Junctional Adhesion Molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness
- (2010) M Götte et al. ONCOGENE
- TGF- promotes invasion and metastasis of gastric cancer cells by increasing fascin1 expression via ERK and JNK signal pathways
- (2009) H. Fu et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Fascin is required for blood cell migration during Drosophila embryogenesis
- (2009) J. Zanet et al. DEVELOPMENT
- Fascin-1 Promoter Activity Is Regulated by CREB and the Aryl Hydrocarbon Receptor in Human Carcinoma Cells
- (2009) Yosuke Hashimoto et al. PLoS One
- Roles of TGFβ in metastasis
- (2008) David Padua et al. CELL RESEARCH
- Assembly and biological role of podosomes and invadopodia
- (2008) Mario Gimona et al. CURRENT OPINION IN CELL BIOLOGY
- Rac regulates the interaction of fascin with protein kinase C in cell migration
- (2008) M. Parsons et al. JOURNAL OF CELL SCIENCE
- Fascin expresion in glial tumors and its prognostic significance in glioblastomas
- (2008) Armagan Gunal et al. NEUROPATHOLOGY
- High-resolution cryo-EM structure of the F-actin-fimbrin/plastin ABD2 complex
- (2008) V. E. Galkin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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