The mitochondrial deoxyguanosine kinase is required for cancer cell stemness in lung adenocarcinoma

Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments

(2019) Shengchen Lin et al.   Cell Reports

Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer

(2018) Yonathan Lissanu Deribe et al.   NATURE MEDICINE

Mitochondrial biology in cancer stem cells

(2017) Rute Loureiro et al.   SEMINARS IN CANCER BIOLOGY

Hallmarks of cancer stem cell metabolism

(2016) Patricia Sancho et al.   BRITISH JOURNAL OF CANCER

NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism

(2016) Chia-Lin Chen et al.   Cell Metabolism

Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools and Remodel One-Carbon Metabolism

(2016) Joni Nikkanen et al.   Cell Metabolism

Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension

(2016) Sílvia Vilarinho et al.   HEPATOLOGY

Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas

(2016) Joshua D Campbell et al.   NATURE GENETICS

Control of YAP/TAZ Activity by Metabolic and Nutrient-Sensing Pathways

(2016) Giulia Santinon et al.   TRENDS IN CELL BIOLOGY

Mitochondrial DNA copy number variation across human cancers

(2016) Ed Reznik et al.   eLife

Cancer statistics, 2015

(2015) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The sweet side of YAP/TAZ

(2015) Giulia Santinon et al.   CELL CYCLE

MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells

(2015) Patricia Sancho et al.   Cell Metabolism

TPO-Induced Metabolic Reprogramming Drives Liver Metastasis of Colorectal Cancer CD110+ Tumor-Initiating Cells

(2015) ZhengMing Wu et al.   Cell Stem Cell

Aerobic glycolysis tunes YAP/TAZ transcriptional activity

(2015) E. Enzo et al.   EMBO JOURNAL

Regulation of deoxynucleotide metabolism in cancer: novel mechanisms and therapeutic implications

(2015) Rebecca Kohnken et al.   Molecular Cancer

Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway

(2015) Jung-Soon Mo et al.   NATURE CELL BIOLOGY

AMPK modulates Hippo pathway activity to regulate energy homeostasis

(2015) Wenqi Wang et al.   NATURE CELL BIOLOGY

Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non–Small Cell Lung Cancer

(2015) Namrata Bora-Singhal et al.   NEOPLASIA

Zidovudine Induces Downregulation of Mitochondrial Deoxynucleoside Kinases: Implications for Mitochondrial Toxicity of Antiviral Nucleoside Analogs

(2014) Ren Sun et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Down-regulation of mitochondrial thymidine kinase 2 and deoxyguanosine kinase by didanosine: Implication for mitochondrial toxicities of anti-HIV nucleoside analogs

(2014) Ren Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Essential Role of Aldehyde Dehydrogenase 1A3 for the Maintenance of Non-Small Cell Lung Cancer Stem Cells Is Associated with the STAT3 Pathway

(2014) C. Shao et al.   CLINICAL CANCER RESEARCH

STIM1- and Orai1-mediated Ca2+oscillation orchestrates invadopodium formation and melanoma invasion

(2014) Jianwei Sun et al.   JOURNAL OF CELL BIOLOGY

Metabolic control of YAP and TAZ by the mevalonate pathway

(2014) Giovanni Sorrentino et al.   NATURE CELL BIOLOGY

Energy Stress Regulates Hippo-YAP Signaling Involving AMPK-Mediated Regulation of Angiomotin-like 1 Protein

(2014) Michael DeRan et al.   Cell Reports

Iterative rank-order normalization of gene expression microarray data

(2013) Eric A Welsh et al.   BMC BIOINFORMATICS

Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer

(2013) Chenfang Dong et al.   CANCER CELL

Mitochondrial DNA Depletion Syndromes: Review and Updates of Genetic Basis, Manifestations, and Therapeutic Options

(2013) Ayman W. El-Hattab et al.   Neurotherapeutics

Next-generation sequencing reveals DGUOK mutations in adult patients with mitochondrial DNA multiple deletions

(2012) D. Ronchi et al.   BRAIN

Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis

(2012) Wen Cai Zhang et al.   CELL

Metabolic Plasticity in Stem Cell Homeostasis and Differentiation

(2012) Clifford D.L. Folmes et al.   Cell Stem Cell

Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells

(2012) M. Janiszewska et al.   GENES & DEVELOPMENT

Survival of Cancer Stem Cells under Hypoxia and Serum Depletion via Decrease in PP2A Activity and Activation of p38-MAPKAPK2-Hsp27

(2012) Shih-Pei Lin et al.   PLoS One

Mitochondrial and energy metabolism-related properties as novel indicators of lung cancer stem cells

(2011) Xiao-Qun Ye et al.   INTERNATIONAL JOURNAL OF CANCER

A novel fluorescence-based assay for the rapid detection and quantification of cellular deoxyribonucleoside triphosphates

(2011) Peter M. Wilson et al.   NUCLEIC ACIDS RESEARCH

A Perspective on Cancer Cell Metastasis

(2011) C. L. Chaffer et al.   SCIENCE

Aldehyde Dehydrogenase Activity Selects for Lung Adenocarcinoma Stem Cells Dependent on Notch Signaling

(2010) J. P. Sullivan et al.   CANCER RESEARCH

Molecular Gene Therapy: Overexpression of the Alternative NADH Dehydrogenase NDI1 Restores Overall Physiology in a Fungal Model of Respiratory Complex I Deficiency

(2010) Marc F.P.M. Maas et al.   JOURNAL OF MOLECULAR BIOLOGY

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Orai1 and STIM1 Are Critical for Breast Tumor Cell Migration and Metastasis

(2009) Shengyu Yang et al.   CANCER CELL

In vitro supplementation with dAMP/dGMP leads to partial restoration of mtDNA levels in mitochondrial depletion syndromes

(2009) S. Bulst et al.   HUMAN MOLECULAR GENETICS

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY