Fascin Is Critical for the Maintenance of Breast Cancer Stem Cell Pool Predominantly via the Activation of the Notch Self-Renewal Pathway

Fascin is involved in the chemotherapeutic resistance of breast cancer cells predominantly via the PI3K/Akt pathway

(2014) H Ghebeh et al.   BRITISH JOURNAL OF CANCER

Fascin Is Regulated by Slug, Promotes Progression of Pancreatic Cancer in Mice, and Is Associated With Patient Outcomes

(2014) Ang Li et al.   GASTROENTEROLOGY

Profiling of normal and malignant breast tissue show CD44high/CD24lowphenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers

(2013) Hazem Ghebeh et al.   BMC CANCER

Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells

(2013) S Suman et al.   BRITISH JOURNAL OF CANCER

Disulfiram targets cancer stem-like cells and reverses resistance and cross-resistance in acquired paclitaxel-resistant triple-negative breast cancer cells

(2013) P Liu et al.   BRITISH JOURNAL OF CANCER

The Notch signaling pathway as a mediator of tumor survival

(2013) K. M. Capaccione et al.   CARCINOGENESIS

Tumor-Associated Microglia/Macrophages Enhance the Invasion of Glioma Stem-like Cells via TGF- 1 Signaling Pathway

(2012) X.-z. Ye et al.   JOURNAL OF IMMUNOLOGY

Nicastrin regulates breast cancer stem cell properties and tumor growth in vitro and in vivo

(2012) Y. Lombardo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stem cells in squamous head and neck cancer

(2011) Andreas E. Albers et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Human primary bone sarcomas contain CD133+ cancer stem cells displaying high tumorigenicity in vivo

(2011) Virginia Tirino et al.   FASEB JOURNAL

Fascin Is a Key Regulator of Breast Cancer Invasion That Acts via the Modification of Metastasis-Associated Molecules

(2011) Monther Al-Alwan et al.   PLoS One

Antagonistic roles of Notch and p63 in controlling mammary epithelial cell fates

(2010) Ö Yalcin-Ozuysal et al.   CELL DEATH AND DIFFERENTIATION

Migrastatin analogues target fascin to block tumour metastasis

(2010) Lin Chen et al.   NATURE

Lung cancer stem cells: tools and targets to fight lung cancer

(2010) A Eramo et al.   ONCOGENE

Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion

(2009) J Chen et al.   BRITISH JOURNAL OF CANCER

ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

(2009) Yifang Hu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Cancer stem cells: mirage or reality?

(2009) Piyush B Gupta et al.   NATURE MEDICINE

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Transcriptome Analysis of the Normal Human Mammary Cell Commitment and Differentiation Process

(2008) Afshin Raouf et al.   Cell Stem Cell

Identification of cells initiating human melanomas

(2008) Tobias Schatton et al.   NATURE