Better to keep in touch: investigating inter‐organelle cross‐talk

ORP3 phosphorylation regulates phosphatidylinositol 4-phosphate and Ca2+ dynamics at PM-ER contact sites

(2020) Gergő Gulyás et al.   JOURNAL OF CELL SCIENCE

Nanoscale subcellular architecture revealed by multicolor three-dimensional salvaged fluorescence imaging

(2020) Yongdeng Zhang et al.   NATURE METHODS

Endoplasmic reticulum–plasma membrane contacts: Principals of phosphoinositide and calcium signaling

(2020) Christopher J. Stefan   CURRENT OPINION IN CELL BIOLOGY

ESCRT-III and ER–PM contacts maintain lipid homeostasis

(2020) Jeff R. Jorgensen et al.   MOLECULAR BIOLOGY OF THE CELL

Pharmacological modulation of mitochondrial calcium uniporter controls lung inflammation in cystic fibrosis

(2020) Alessandro Rimessi et al.   Science Advances

The activity of Sac1 across ER–TGN contact sites requires the four-phosphate-adaptor-protein-1

(2019) Rossella Venditti et al.   JOURNAL OF CELL BIOLOGY

Molecular determinants of ER–Golgi contacts identified through a new FRET–FLIM system

(2019) Rossella Venditti et al.   JOURNAL OF CELL BIOLOGY

SR-mitochondria communication in adult cardiomyocytes: A close relationship where the Ca2+ has a lot to say

(2019) Sergio De la Fuente et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

SMP domain proteins in membrane lipid dynamics

(2019) Darshini Jeyasimman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A genetically encoded toolkit of functionalized nanobodies against fluorescent proteins for visualizing and manipulating intracellular signalling

(2019) David L. Prole et al.   BMC BIOLOGY

Redox regulation of ER and mitochondrial Ca2+ signaling in cell survival and death

(2019) Suresh K. Joseph et al.   CELL CALCIUM

Crosstalk between Calcium and ROS in Pathophysiological Conditions

(2019) Simona Feno et al.   Oxidative Medicine and Cellular Longevity

Remodeling of ER–plasma membrane contact sites but not STIM1 phosphorylation inhibits Ca2+ influx in mitosis

(2019) Fang Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interorganellar calcium signaling in the regulation of cell metabolism: A cancer perspective

(2019) Alessandro Rimessi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Structure, functions and regulation of CERT, a lipid‐transfer protein for the delivery of ceramide at the ER–Golgi membrane contact sites

(2019) Keigo Kumagai et al.   FEBS LETTERS

FÖrster resonance energy transfer (FRET)-based biosensors for biological applications

(2019) Xiaojing Zhang et al.   BIOSENSORS & BIOELECTRONICS

ER Ca2+ release and store-operated Ca2+ entry – partners in crime or independent actors in oncogenic transformation?

(2019) Cristina Pierro et al.   CELL CALCIUM

ER-Mitochondria Communication in Cells of the Innate Immune System

(2019) Dmitry Namgaladze et al.   Cells

The functional universe of membrane contact sites

(2019) William A. Prinz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Plant AtEH/Pan1 proteins drive autophagosome formation at ER-PM contact sites with actin and endocytic machinery

(2019) Pengwei Wang et al.   Nature Communications

Endoplasmic reticulum chaperones tweak the mitochondrial calcium rheostat to control metabolism and cell death

(2018) Tomas Gutiérrez et al.   CELL CALCIUM

Mitochondria Bound to Lipid Droplets Have Unique Bioenergetics, Composition, and Dynamics that Support Lipid Droplet Expansion

(2018) Ilan Y. Benador et al.   Cell Metabolism

The ER Contact Proteins VAPA/B Interact with Multiple Autophagy Proteins to Modulate Autophagosome Biogenesis

(2018) Yan G. Zhao et al.   CURRENT BIOLOGY

Interacting organelles

(2018) Sarah Cohen et al.   CURRENT OPINION IN CELL BIOLOGY

Mitochondria–lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis

(2018) Yvette C. Wong et al.   NATURE

Cargo recognition and degradation by selective autophagy

(2018) Damián Gatica et al.   NATURE CELL BIOLOGY

Highlighting the endoplasmic reticulum-mitochondria connection: Focus on Mitofusin 2

(2018) Riccardo Filadi et al.   PHARMACOLOGICAL RESEARCH

Endoplasmic Reticulum–Mitochondrial Contactology: Structure and Signaling Functions

(2018) György Csordás et al.   TRENDS IN CELL BIOLOGY

Systematic mapping of contact sites reveals tethers and a function for the peroxisome-mitochondria contact

(2018) Nadav Shai et al.   Nature Communications

Visualizing multiple inter-organelle contact sites using the organelle-targeted split-GFP system

(2018) Yuriko Kakimoto et al.   Scientific Reports

Visualizing and discovering cellular structures with super-resolution microscopy

(2018) Yaron M. Sigal et al.   SCIENCE

Calcium, mitochondria and cell metabolism: A functional triangle in bioenergetics

(2018) Alice Rossi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Epithelial-Mesenchymal Transition Directs Stem Cell Polarity via Regulation of Mitofusin

(2018) Meng-Ju Wu et al.   Cell Metabolism

A Bayesian mixture modelling approach for spatial proteomics

(2018) Oliver M. Crook et al.   PLoS Computational Biology

Phosphatidylserine synthesis at membrane contact sites promotes its transport out of the ER

(2017) Muthukumar Kannan et al.   JOURNAL OF LIPID RESEARCH

The ER Stress Sensor PERK Coordinates ER-Plasma Membrane Contact Site Formation through Interaction with Filamin-A and F-Actin Remodeling

(2017) Alexander R. van Vliet et al.   MOLECULAR CELL

Applying systems-level spectral imaging and analysis to reveal the organelle interactome

(2017) Alex M. Valm et al.   NATURE

Mitochondria-Associated Membranes Response to Nutrient Availability and Role in Metabolic Diseases

(2017) Pierre Theurey et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

ROS Control Mitochondrial Motility through p38 and the Motor Adaptor Miro/Trak

(2017) Valentina Debattisti et al.   Cell Reports

Endoplasmic Reticulum–Mitochondria Calcium Communication and the Regulation of Mitochondrial Metabolism in Cancer: A Novel Potential Target

(2017) Galdo Bustos et al.   Frontiers in Oncology

Structure, Activity Regulation, and Role of the Mitochondrial Calcium Uniporter in Health and Disease

(2017) Cristina Mammucari et al.   Frontiers in Oncology

ER functions of oncogenes and tumor suppressors: Modulators of intracellular Ca 2+ signaling

(2016) Mart Bittremieux et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport

(2016) Marlieke L.M. Jongsma et al.   CELL

The coming of age of the mitochondria–ER contact: a matter of thickness

(2016) M Giacomello et al.   CELL DEATH AND DIFFERENTIATION

TMX1 determines cancer cell metabolism as a thiol-based modulator of ER–mitochondria Ca2+flux

(2016) Arun Raturi et al.   JOURNAL OF CELL BIOLOGY

Num1 anchors mitochondria to the plasma membrane via two domains with different lipid binding specificities

(2016) Holly A. Ping et al.   JOURNAL OF CELL BIOLOGY

Redox Nanodomains Are Induced by and Control Calcium Signaling at the ER-Mitochondrial Interface

(2016) David M. Booth et al.   MOLECULAR CELL

Multiple dynamin family members collaborate to drive mitochondrial division

(2016) Jason E. Lee et al.   NATURE

ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells

(2016) Samantha C. Lewis et al.   SCIENCE

There's Something Wrong with my MAM; the ER–Mitochondria Axis and Neurodegenerative Diseases

(2016) Sebastien Paillusson et al.   TRENDS IN NEUROSCIENCES

Presenilin 2 Modulates Endoplasmic Reticulum-Mitochondria Coupling by Tuning the Antagonistic Effect of Mitofusin 2

(2016) Riccardo Filadi et al.   Cell Reports

Global, quantitative and dynamic mapping of protein subcellular localization

(2016) Daniel N Itzhak et al.   eLife

Ultrastructural relationship of the phagophore with surrounding organelles

(2015) Joanna Biazik et al.   Autophagy

Generation and functions of second messengers microdomains

(2015) Riccardo Filadi et al.   CELL CALCIUM

Analysis of ER-mitochondria contacts using correlative fluorescence microscopy and soft X-ray tomography of mammalian cells

(2015) K. D. Elgass et al.   JOURNAL OF CELL SCIENCE

Proteomic mapping of ER–PM junctions identifies STIMATE as a regulator of Ca2+ influx

(2015) Ji Jing et al.   NATURE CELL BIOLOGY

Three-dimensional architecture of extended synaptotagmin-mediated endoplasmic reticulum–plasma membrane contact sites

(2015) Rubén Fernández-Busnadiego et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitofusin 2 ablation increases endoplasmic reticulum–mitochondria coupling

(2015) Riccardo Filadi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis

(2015) Alessandro Rimessi et al.   Nature Communications

dPob/EMC is essential for biosynthesis of rhodopsin and other multi-pass membrane proteins in Drosophila photoreceptors

(2015) Takunori Satoh et al.   eLife

ER Contact Sites Define the Position and Timing of Endosome Fission

(2014) Ashley A. Rowland et al.   CELL

A Dynamic Interface between Vacuoles and Mitochondria in Yeast

(2014) Yael Elbaz-Alon et al.   DEVELOPMENTAL CELL

Mitochondrial ER Contacts Are Crucial for Mitophagy in Yeast

(2014) Stefan Böckler et al.   DEVELOPMENTAL CELL

SEPN1, an endoplasmic reticulum-localized selenoprotein linked to skeletal muscle pathology, counteracts hyperoxidation by means of redox-regulating SERCA2 pump activity

(2014) Marianna Marino et al.   HUMAN MOLECULAR GENETICS

Isoform- and Species-specific Control of Inositol 1,4,5-Trisphosphate (IP3) Receptors by Reactive Oxygen Species

(2014) Száva Bánsághi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Conserved Endoplasmic Reticulum Membrane Protein Complex (EMC) Facilitates Phospholipid Transfer from the ER to Mitochondria

(2014) Sujoy Lahiri et al.   PLOS BIOLOGY

Spying on organelle Ca2+ in living cells: the mitochondrial point of view

(2014) D. Pendin et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

PI(4,5)P2-Dependent and Ca2+-Regulated ER-PM Interactions Mediated by the Extended Synaptotagmins

(2013) Francesca Giordano et al.   CELL

ER exit sites are physical and functional core autophagosome biogenesis components

(2013) Martin Graef et al.   MOLECULAR BIOLOGY OF THE CELL

Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins

(2013) Kenji Maeda et al.   NATURE

Autophagosomes form at ER–mitochondria contact sites

(2013) Maho Hamasaki et al.   NATURE

Sigma-1 Receptor Chaperone at the ER-Mitochondrion Interface Mediates the Mitochondrion-ER-Nucleus Signaling for Cellular Survival

(2013) Tomohisa Mori et al.   PLoS One

Endoplasmic reticulum-associated mitochondria-cortex tether functions in the distribution and inheritance of mitochondria

(2013) L. L. Lackner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2

(2013) F. Korobova et al.   SCIENCE

ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast

(2013) Andrew Murley et al.   eLife

PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress

(2012) T Verfaillie et al.   CELL DEATH AND DIFFERENTIATION

Upregulated function of mitochondria-associated ER membranes in Alzheimer disease

(2012) Estela Area-Gomez et al.   EMBO JOURNAL

Dimerization-Dependent Green and Yellow Fluorescent Proteins

(2012) Spencer C. Alford et al.   ACS Synthetic Biology

Uncoupling Protein 3 (UCP3) Modulates the Activity of Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) by Decreasing Mitochondrial ATP Production

(2011) Umberto De Marchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress

(2011) R. Bravo et al.   JOURNAL OF CELL SCIENCE

In VivoAnalysis of Proteomes and Interactomes Using Parallel Affinity Capture (iPAC) Coupled to Mass Spectrometry

(2011) Johanna S. Rees et al.   MOLECULAR & CELLULAR PROTEOMICS

Targeting and imaging single biomolecules in living cells by complementation-activated light microscopy with split-fluorescent proteins

(2011) F. Pinaud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ER Tubules Mark Sites of Mitochondrial Division

(2011) J. R. Friedman et al.   SCIENCE

Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress

(2010) L Bouman et al.   CELL DEATH AND DIFFERENTIATION

Imaging cellular architecture with X-rays

(2010) Carolyn A Larabell et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Ca2+ Hot Spots on the Mitochondrial Surface Are Generated by Ca2+ Mobilization from Stores, but Not by Activation of Store-Operated Ca2+ Channels

(2010) Marta Giacomello et al.   MOLECULAR CELL

Imaging Interorganelle Contacts and Local Calcium Dynamics at the ER-Mitochondrial Interface

(2010) György Csordás et al.   MOLECULAR CELL

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Membrane contacts between endosomes and ER provide sites for PTP1B–epidermal growth factor receptor interaction

(2010) Emily R. Eden et al.   NATURE CELL BIOLOGY

Super-resolution video microscopy of live cells by structured illumination

(2009) Peter Kner et al.   NATURE METHODS

Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells

(2009) Mariusz R Wieckowski et al.   Nature Protocols

Role of SERCA1 Truncated Isoform in the Proapoptotic Calcium Transfer from ER to Mitochondria during ER Stress

(2008) Mounia Chami et al.   MOLECULAR CELL

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE

Directional conjugation of antibodies to nanoparticles for synthesis of multiplexed optical contrast agents with both delivery and targeting moieties

(2008) S Kumar et al.   Nature Protocols