Structure, functions and regulation of CERT, a lipid‐transfer protein for the delivery of ceramide at the ER–Golgi membrane contact sites

Molecular determinants of ER–Golgi contacts identified through a new FRET–FLIM system

(2019) Rossella Venditti et al.   JOURNAL OF CELL BIOLOGY

Regulation of glucosylceramide synthesis by Golgi-localized phosphoinositide

(2018) Yohei Ishibashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Phosphoinositide binding by the PH domain in ceramide transfer protein (CERT) is inhibited by hyperphosphorylation of an adjacent serine-repeat motif

(2018) Toshihiko Sugiki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid-transfer proteins rectify inter-organelle flux and accurately deliver lipids at membrane contact sites

(2018) Kentaro Hanada   JOURNAL OF LIPID RESEARCH

Ceramide-transfer protein-mediated ceramide transfer is a structurally tunable flow-inducing mechanism with structural feed-forward loops

(2018) Giulia Giordano   Royal Society Open Science

Role of DGAT enzymes in triacylglycerol metabolism

(2018) Bhumika Bhatt-Wessel et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Complex formation of sphingomyelin synthase 1 with glucosylceramide synthase increases sphingomyelin and decreases glucosylceramide levels

(2018) Yasuhiro Hayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Both the N- and C- terminal regions of the Chlamydial inclusion protein D (IncD) are required for interaction with the pleckstrin homology domain of the ceramide transport protein CERT

(2018) Keigo Kumagai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Unicellular ancestry and mechanisms of diversification of Goodpasture antigen–binding protein

(2018) Carl Darris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction between the PH and START domains of ceramide transfer protein competes with phosphatidylinositol 4-phosphate binding by the PH domain

(2017) Jennifer Prashek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VAP, a Versatile Access Point for the Endoplasmic Reticulum: Review and analysis of FFAT-like motifs in the VAPome

(2016) Sarah E. Murphy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Proteogenomics connects somatic mutations to signalling in breast cancer

(2016) Philipp Mertins et al.   NATURE

A computational model of PKD and CERT interactions at the trans-Golgi network of mammalian cells

(2015) Patrick Weber et al.   BMC Systems Biology

Oxysterol-binding Protein Activation at Endoplasmic Reticulum-Golgi Contact Sites Reorganizes Phosphatidylinositol 4-Phosphate Pools

(2015) Asako Goto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphoregulation of the Ceramide Transport Protein CERT at Serine 315 in the Interaction with VAMP-associated Protein (VAP) for Inter-organelle Trafficking of Ceramide in Mammalian Cells

(2014) Keigo Kumagai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Large-scale discovery of novel genetic causes of developmental disorders

(2014) T. W. Fitzgerald et al.   NATURE

Ceramide Transfer Protein Deficiency Compromises Organelle Function and Leads to Senescence in Primary Cells

(2014) Raghavendra Pralhada Rao et al.   PLoS One

Establishment of HeLa Cell Mutants Deficient in Sphingolipid-Related Genes Using TALENs

(2014) Toshiyuki Yamaji et al.   PLoS One

Sphingolipid Metabolism and Interorganellar Transport: Localization of Sphingolipid Enzymes and Lipid Transfer Proteins

(2014) Toshiyuki Yamaji et al.   TRAFFIC

Ultradeep Human Phosphoproteome Reveals a Distinct Regulatory Nature of Tyr and Ser/Thr-Based Signaling

(2014) Kirti Sharma et al.   Cell Reports

De Novo Mutations in Moderate or Severe Intellectual Disability

(2014) Fadi F. Hamdan et al.   PLoS Genetics

Co-evolution of sphingomyelin and the ceramide transport protein CERT

(2013) Kentaro Hanada   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A Four-Step Cycle Driven by PI(4)P Hydrolysis Directs Sterol/PI(4)P Exchange by the ER-Golgi Tether OSBP

(2013) Bruno Mesmin et al.   CELL

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome

(2013) Yangyang Bian et al.   Journal of Proteomics

Diagnostic Exome Sequencing in Persons With Severe Intellectual Disability

(2013) Joep de Ligt et al.   OBSTETRICAL & GYNECOLOGICAL SURVEY

Structural Basis for the Golgi Association by the Pleckstrin Homology Domain of the Ceramide Trafficking Protein (CERT)

(2012) Toshihiko Sugiki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycosylphosphatidylinositol anchors regulate glycosphingolipid levels

(2012) Ursula Loizides-Mangold et al.   JOURNAL OF LIPID RESEARCH

Toward a Comprehensive Characterization of a Human Cancer Cell Phosphoproteome

(2012) Houjiang Zhou et al.   JOURNAL OF PROTEOME RESEARCH

Analysis of the Key Elements of FFAT-Like Motifs Identifies New Proteins That Potentially Bind VAP on the ER, Including Two AKAPs and FAPP2

(2012) Veronika Mikitova et al.   PLoS One

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues

(2012) Alicia Lundby et al.   Nature Communications

Inactivation of ceramide transfer protein during pro-apoptotic stress by Golgi disassembly and caspase cleavage

(2011) Suchismita Chandran et al.   BIOCHEMICAL JOURNAL

Protein Kinase D Negatively Regulates Hepatitis C Virus Secretion through Phosphorylation of Oxysterol-binding Protein and Ceramide Transfer Protein

(2011) Yutaka Amako et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers

(2011) Maud de Saint-Jean et al.   JOURNAL OF CELL BIOLOGY

The Lipid Transfer Protein CERT Interacts with the Chlamydia Inclusion Protein IncD and Participates to ER-Chlamydia Inclusion Membrane Contact Sites

(2011) Isabelle Derré et al.   PLoS Pathogens

A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression

(2010) Edward L. Huttlin et al.   CELL

Electrostatic Interaction between Oxysterol-binding Protein and VAMP-associated Protein A Revealed by NMR and Mutagenesis Studies

(2010) Kyoko Furuita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxysterol Binding Protein-dependent Activation of Sphingomyelin Synthesis in the Golgi Apparatus Requires Phosphatidylinositol 4-Kinase IIα

(2010) Sangeeta Banerji et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of Oxysterol-binding Protein Golgi Localization through Protein Kinase D–mediated Phosphorylation

(2010) Sokha Nhek et al.   MOLECULAR BIOLOGY OF THE CELL

Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice

(2009) Xin Wang et al.   JOURNAL OF CELL BIOLOGY

Use of high performance liquid chromatography-electrospray ionization-tandem mass spectrometry for the analysis of ceramide-1-phosphate levels

(2009) Dayanjan S. Wijesinghe et al.   JOURNAL OF LIPID RESEARCH

Goodpasture Antigen-binding Protein Is a Soluble Exportable Protein That Interacts with Type IV Collagen

(2008) Fernando Revert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decreased Ceramide Transport Protein (CERT) Function Alters Sphingomyelin Production following UVB Irradiation

(2008) Alexandra Charruyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The multiple roles of PtdIns(4)P - not just the precursor of PtdIns(4,5)P2

(2008) G. D'Angelo et al.   JOURNAL OF CELL SCIENCE

Casein Kinase Iγ2 Down-Regulates Trafficking of Ceramide in the Synthesis of Sphingomyelin

(2008) Nario Tomishige et al.   MOLECULAR BIOLOGY OF THE CELL

Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide

(2008) N. Kudo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A quantitative atlas of mitotic phosphorylation

(2008) N. Dephoure et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography

(2008) Guanghui Han et al.   PROTEOMICS