A proposed role for the SARS‐CoV‐2 nucleocapsid protein in the formation and regulation of biomolecular condensates
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Title
A proposed role for the SARS‐CoV‐2 nucleocapsid protein in the formation and regulation of biomolecular condensates
Authors
Keywords
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Journal
FASEB JOURNAL
Volume 34, Issue 8, Pages 9832-9842
Publisher
Wiley
Online
2020-07-30
DOI
10.1096/fj.202001351
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Note: Only part of the references are listed.- Modulation of RNA Condensation by the DEAD-Box Protein eIF4A
- (2020) Devin Tauber et al. CELL
- RNase L promotes the formation of unique ribonucleoprotein granules distinct from stress granules
- (2020) James M. Burke et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Novel Coronavirus from Patients with Pneumonia in China, 2019
- (2020) Na Zhu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Serine-Arginine Protein Kinase 1 Regulates Ebola Virus Transcription
- (2020) Yuki Takamatsu et al. mBio
- Atypical structural tendencies among low-complexity domains in the Protein Data Bank proteome
- (2020) Sean M. Cascarina et al. PLoS Computational Biology
- Norovirus infection results in eIF2α independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation
- (2020) Michèle Brocard et al. PLoS Pathogens
- Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan
- (2020) Jasper Fuk-Woo Chan et al. Emerging Microbes & Infections
- Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization
- (2020) David W. Sanders et al. CELL
- G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules
- (2020) Peiguo Yang et al. CELL
- Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
- (2020) Daniel Blanco-Melo et al. CELL
- RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation
- (2020) Jordina Guillén-Boixet et al. CELL
- A Sequence Homology and Bioinformatic Approach Can Predict Candidate Targets for Immune Responses to SARS-CoV-2
- (2020) Alba Grifoni et al. Cell Host & Microbe
- Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients
- (2020) Zhuo Zhou et al. Cell Host & Microbe
- RNase L amplifies interferon signaling by inducing PKR-mediated antiviral stress granules
- (2020) Praveen Manivannan et al. JOURNAL OF VIROLOGY
- A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
- (2020) David E. Gordon et al. NATURE
- Coronavirus endoribonuclease targets viral polyuridine sequences to evade activating host sensors
- (2020) Matthew Hackbart et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pan-retroviral Nucleocapsid-Mediated Phase Separation Regulates Genomic RNA Positioning and Trafficking
- (2020) Anne Monette et al. Cell Reports
- Measles virus nucleo- and phosphoproteins form liquid-like phase-separated compartments that promote nucleocapsid assembly
- (2020) Serafima Guseva et al. Science Advances
- Stoichiometry controls activity of phase-separated clusters of actin signaling proteins
- (2019) Lindsay B. Case et al. SCIENCE
- The stress granule protein G3BP1 binds viral dsRNA and RIG-I to enhance IFN-β response
- (2019) Susana Soo-Yeon Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Double-Stranded RNA Sensors and Modulators in Innate Immunity
- (2019) Sun Hur Annual Review of Immunology
- ZAP’s stress granule localization is correlated with its antiviral activity and induced by virus replication
- (2019) Lok Man John Law et al. PLoS Pathogens
- Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation
- (2019) David Trombley McSwiggen et al. eLife
- Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites
- (2019) Marta Alenquer et al. Nature Communications
- Liquid–Liquid Phase Separation in Disease
- (2019) Simon Alberti et al. Annual Review of Genetics
- Measles Virus Forms Inclusion Bodies with Properties of Liquid Organelles
- (2019) Yuqin Zhou et al. JOURNAL OF VIROLOGY
- Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation
- (2019) Myra Hosmillo et al. eLife
- The prion-like protein kinase Sky1 is required for efficient stress granule disassembly
- (2019) Jenifer E. Shattuck et al. Nature Communications
- Strategies for Success. Viral Infections and Membraneless Organelles
- (2019) Aracelly Gaete-Argel et al. Frontiers in Cellular and Infection Microbiology
- A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins
- (2018) Jie Wang et al. CELL
- Accessory proteins 8b and 8ab of severe acute respiratory syndrome coronavirus suppress the interferon signaling pathway by mediating ubiquitin-dependent rapid degradation of interferon regulatory factor 3
- (2018) Hui Hui Wong et al. VIROLOGY
- Pi-Pi contacts are an overlooked protein feature relevant to phase separation
- (2018) Robert McCoy Vernon et al. eLife
- Inhibition of Stress Granule Formation by Middle East Respiratory Syndrome Coronavirus 4a Accessory Protein Facilitates Viral Translation, Leading to Efficient Virus Replication
- (2018) Keisuke Nakagawa et al. JOURNAL OF VIROLOGY
- Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments
- (2018) Bianca S. Heinrich et al. mBio
- Proteome-scale relationships between local amino acid composition and protein fates and functions
- (2018) Sean M. Cascarina et al. PLoS Computational Biology
- An Integrative Study of Protein-RNA Condensates Identifies Scaffolding RNAs and Reveals Players in Fragile X-Associated Tremor/Ataxia Syndrome
- (2018) Fernando Cid-Samper et al. Cell Reports
- Hepatitis B virus core protein phosphorylation: Identification of the SRPK1 target sites and impact of their occupancy on RNA binding and capsid structure
- (2018) Julia Heger-Stevic et al. PLoS Pathogens
- Zika Virus Hijacks Stress Granule Proteins and Modulates the Host Stress Response
- (2017) Shangmei Hou et al. JOURNAL OF VIROLOGY
- The Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Inhibits Type I Interferon Production by Interfering with TRIM25-Mediated RIG-I Ubiquitination
- (2017) Yong Hu et al. JOURNAL OF VIROLOGY
- Liquid behavior of cross-linked actin bundles
- (2017) Kimberly L. Weirich et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stress Granule-Inducing Eukaryotic Translation Initiation Factor 4A Inhibitors Block Influenza A Virus Replication
- (2017) Patrick Slaine et al. Viruses-Basel
- Negri bodies are viral factories with properties of liquid organelles
- (2017) Jovan Nikolic et al. Nature Communications
- Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase
- (2017) Amayra Hernández-Vega et al. Cell Reports
- The integrated stress response
- (2016) Karolina Pakos‐Zebrucka et al. EMBO REPORTS
- Lineage A Betacoronavirus NS2 Proteins and the Homologous Torovirus Berne pp1a Carboxy-Terminal Domain Are Phosphodiesterases That Antagonize Activation of RNase L
- (2016) Stephen A. Goldstein et al. JOURNAL OF VIROLOGY
- A Concentration-Dependent Liquid Phase Separation Can Cause Toxicity upon Increased Protein Expression
- (2016) Benedetta Bolognesi et al. Cell Reports
- Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses
- (2016) Huib H. Rabouw et al. PLoS Pathogens
- Leader-Containing Uncapped Viral Transcript Activates RIG-I in Antiviral Stress Granules
- (2016) Seong-Wook Oh et al. PLoS Pathogens
- The Nucleocapsid Protein of Coronaviruses Acts as a Viral Suppressor of RNA Silencing in Mammalian Cells
- (2015) Lei Cui et al. JOURNAL OF VIROLOGY
- Stress Granule Components G3BP1 and G3BP2 Play a Proviral Role Early in Chikungunya Virus Replication
- (2015) Florine E. M. Scholte et al. JOURNAL OF VIROLOGY
- Stress Granules Regulate Double-Stranded RNA-Dependent Protein Kinase Activation through a Complex Containing G3BP1 and Caprin1
- (2015) Lucas C. Reineke et al. mBio
- SARS-Coronavirus Open Reading Frame-9b Suppresses Innate Immunity by Targeting Mitochondria and the MAVS/TRAF3/TRAF6 Signalosome
- (2014) Chong-Shan Shi et al. JOURNAL OF IMMUNOLOGY
- Human Papillomavirus Type 1 E1^E4 Protein Is a Potent Inhibitor of the Serine-Arginine (SR) Protein Kinase SRPK1 and Inhibits Phosphorylation of Host SR Proteins and of the Viral Transcription and Replication Regulator E2
- (2014) E. L. Prescott et al. JOURNAL OF VIROLOGY
- The Stress Granule Protein G3BP1 Recruits Protein Kinase R To Promote Multiple Innate Immune Antiviral Responses
- (2014) Lucas C. Reineke et al. JOURNAL OF VIROLOGY
- Activation of Stress Response Pathways Promotes Formation of Antiviral Granules and Restricts Virus Replication
- (2014) D. K. Rozelle et al. MOLECULAR AND CELLULAR BIOLOGY
- The Coronavirus Nucleocapsid Is a Multifunctional Protein
- (2014) Ruth McBride et al. Viruses-Basel
- DHX36 Enhances RIG-I Signaling by Facilitating PKR-Mediated Antiviral Stress Granule Formation
- (2014) Ji-Seung Yoo et al. PLoS Pathogens
- Influenza A Virus Host Shutoff Disables Antiviral Stress-Induced Translation Arrest
- (2014) Denys A. Khaperskyy et al. PLoS Pathogens
- Encephalomyocarditis Virus Disrupts Stress Granules, the Critical Platform for Triggering Antiviral Innate Immune Responses
- (2013) C. S. Ng et al. JOURNAL OF VIROLOGY
- Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
- (2013) Hong Joo Kim et al. NATURE
- Transient Oligomerization of the SARS-CoV N Protein – Implication for Virus Ribonucleoprotein Packaging
- (2013) Chung-ke Chang et al. PLoS One
- Antagonism of the Interferon-Induced OAS-RNase L Pathway by Murine Coronavirus ns2 Protein Is Required for Virus Replication and Liver Pathology
- (2012) Ling Zhao et al. Cell Host & Microbe
- Severe Acute Respiratory Syndrome Coronavirus Protein nsp1 Is a Novel Eukaryotic Translation Inhibitor That Represses Multiple Steps of Translation Initiation
- (2012) K. G. Lokugamage et al. JOURNAL OF VIROLOGY
- Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity
- (2012) Koji Onomoto et al. PLoS One
- The Polypyrimidine Tract-Binding Protein Affects Coronavirus RNA Accumulation Levels and Relocalizes Viral RNAs to Novel Cytoplasmic Domains Different from Replication-Transcription Sites
- (2011) I. Sola et al. JOURNAL OF VIROLOGY
- SARS Coronavirus nsp1 Protein Induces Template-Dependent Endonucleolytic Cleavage of mRNAs: Viral mRNAs Are Resistant to nsp1-Induced RNA Cleavage
- (2011) Cheng Huang et al. PLoS Pathogens
- Inhibition of Hepatitis C Virus Replication by a Specific Inhibitor of Serine-Arginine-Rich Protein Kinase
- (2010) Y. Karakama et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Formation of Antiviral Cytoplasmic Granules during Orthopoxvirus Infection
- (2010) M. Simpson-Holley et al. JOURNAL OF VIROLOGY
- Stable Formation of Compositionally Unique Stress Granules in Virus-Infected Cells
- (2010) J. Piotrowska et al. JOURNAL OF VIROLOGY
- A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein
- (2009) Wataru Kamitani et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Phosphorylation of the arginine/serine dipeptide-rich motif of the severe acute respiratory syndrome coronavirus nucleocapsid protein modulates its multimerization, translation inhibitory activity and cellular localization
- (2008) Tsui-Yi Peng et al. FEBS Journal
- Glycogen Synthase Kinase-3 Regulates the Phosphorylation of Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Protein and Viral Replication
- (2008) Chia-Hsin Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Severe Acute Respiratory Syndrome Coronavirus Triggers Apoptosis via Protein Kinase R but Is Resistant to Its Antiviral Activity
- (2008) V. Krahling et al. JOURNAL OF VIROLOGY
- Severe Acute Respiratory Syndrome Coronavirus nsp1 Suppresses Host Gene Expression, Including That of Type I Interferon, in Infected Cells
- (2008) K. Narayanan et al. JOURNAL OF VIROLOGY
- Stress granules: the Tao of RNA triage
- (2008) Paul Anderson et al. TRENDS IN BIOCHEMICAL SCIENCES
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