Hepatitis B virus core protein phosphorylation: Identification of the SRPK1 target sites and impact of their occupancy on RNA binding and capsid structure

Hepatitis B Virus Core Protein Dephosphorylation Occurs during Pregenomic RNA Encapsidation

(2018) Qiong Zhao et al.   JOURNAL OF VIROLOGY

All-atom molecular dynamics of the HBV capsid reveals insights into biological function and cryo-EM resolution limits

(2018) Jodi A Hadden et al.   eLife

Structure of Mutant Hepatitis B Core Protein Capsids with Premature Secretion Phenotype

(2018) Bettina Böttcher et al.   JOURNAL OF MOLECULAR BIOLOGY

Polo-like-kinase 1 is a proviral host factor for hepatitis B virus replication

(2017) Ahmed Diab et al.   HEPATOLOGY

Capsid Phosphorylation State and Hepadnavirus Virion Secretion

(2017) Xiaojun Ning et al.   JOURNAL OF VIROLOGY

A Role for the Host DNA Damage Response in Hepatitis B Virus cccDNA Formation—and Beyond?

(2017) Sabrina Schreiner et al.   Viruses-Basel

Nuclear Import of Hepatitis B Virus Capsids and Genome

(2017) Lara Gallucci et al.   Viruses-Basel

Suppression of hepatitis B virus antigen production and replication by wild-type HBV dependently replicating HBV shRNA vectors in vitro and in vivo

(2016) Baosheng Li et al.   ANTIVIRAL RESEARCH

A Slow Maturation Process Renders Hepatitis B Virus Infectious

(2016) Stefan Seitz et al.   Cell Host & Microbe

Intracellular transport and egress of hepatitis B virus

(2016) Marie-Lise Blondot et al.   JOURNAL OF HEPATOLOGY

Entry of hepatitis B and hepatitis D virus into hepatocytes: Basic insights and clinical implications

(2016) Wenhui Li et al.   JOURNAL OF HEPATOLOGY

Cell-Free Hepatitis B Virus Capsid Assembly Dependent on the Core Protein C-Terminal Domain and Regulated by Phosphorylation

(2016) Laurie Ludgate et al.   JOURNAL OF VIROLOGY

HBV maintains electrostatic homeostasis by modulating negative charges from phosphoserine and encapsidated nucleic acids

(2016) Pei-Yi Su et al.   Scientific Reports

Importin β Can Bind Hepatitis B Virus Core Protein and Empty Core-Like Particles and Induce Structural Changes

(2016) Chao Chen et al.   PLoS Pathogens

Mechanisms of Virus Assembly

(2015) Jason D. Perlmutter et al.   Annual Review of Physical Chemistry

HBV cccDNA: viral persistence reservoir and key obstacle for a cure of chronic hepatitis B

(2015) Michael Nassal   GUT

Hepatitis B Virus Core Protein Phosphorylation Sites Affect Capsid Stability and Transient Exposure of the C-terminal Domain

(2015) Lisa Selzer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Whole-Chain Tick Saliva Proteins Presented on Hepatitis B Virus Capsid-Like Particles Induce High-Titered Antibodies with Neutralizing Potential

(2015) Philipp Kolb et al.   PLoS One

Preparation by alkaline treatment and detailed characterisation of empty hepatitis B virus core particles for vaccine and gene therapy applications

(2015) Arnis Strods et al.   Scientific Reports

Bacterial Serine/Threonine Protein Kinases in Host-Pathogen Interactions

(2014) Marc J. Canova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-free hepatitis B virion levels in patient sera as a potential marker to monitor response to antiviral therapy

(2014) L. Luckenbaugh et al.   JOURNAL OF VIRAL HEPATITIS

Diversity in ATP concentrations in a single bacterial cell population revealed by quantitative single-cell imaging

(2014) Hideyuki Yaginuma et al.   Scientific Reports

3.5Å cryoEM Structure of Hepatitis B Virus Core Assembled from Full-Length Core Protein

(2013) Xuekui Yu et al.   PLoS One

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Cyclin-Dependent Kinase 2 Phosphorylates S/T-P Sites in the Hepadnavirus Core Protein C-Terminal Domain and Is Incorporated into Viral Capsids

(2012) L. Ludgate et al.   JOURNAL OF VIROLOGY

Host factors involved in hepatitis B virus maturation, assembly, and egress

(2012) Reinhild Prange   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Structural Organization of Pregenomic RNA and the Carboxy-Terminal Domain of the Capsid Protein of Hepatitis B Virus

(2012) Joseph C.-Y. Wang et al.   PLoS Pathogens

Serine Phosphoacceptor Sites within the Core Protein of Hepatitis B Virus Contribute to Genome Replication Pleiotropically

(2011) Eric B. Lewellyn et al.   PLoS One

Targeting the hepatitis B virus precore antigen with a novel IgNAR single variable domain intrabody

(2011) Renae Walsh et al.   VIROLOGY

SplitCore: An exceptionally versatile viral nanoparticle for native whole protein display regardless of 3D structure

(2011) Andreas Walker et al.   Scientific Reports

A Kinase Chaperones Hepatitis B Virus Capsid Assembly and Captures Capsid Dynamics in vitro

(2011) Chao Chen et al.   PLoS Pathogens

Secretion of Genome-Free Hepatitis B Virus – Single Strand Blocking Model for Virion Morphogenesis of Para-retrovirus

(2011) Xiaojun Ning et al.   PLoS Pathogens

Inhibition of protein kinase C phosphorylation of hepatitis B virus capsids inhibits virion formation and causes intracellular capsid accumulation

(2010) Linda Wittkop et al.   CELLULAR MICROBIOLOGY

Quantitative assessment of the antiviral potencies of 21 shRNA vectors targeting conserved, including structured, hepatitis B virus sites

(2010) Dianxing Sun et al.   JOURNAL OF HEPATOLOGY

Full-Length Hepatitis B Virus Core Protein Packages Viral and Heterologous RNA with Similarly High Levels of Cooperativity

(2010) J. Z. Porterfield et al.   JOURNAL OF VIROLOGY

A simple and general method for determining the protein and nucleic acid content of viruses by UV absorbance

(2010) J. Zachary Porterfield et al.   VIROLOGY

Generation of Covalently Closed Circular DNA of Hepatitis B Viruses via Intracellular Recycling Is Regulated in a Virus Specific Manner

(2010) Josef Köck et al.   PLoS Pathogens

Nuclear Export and Import of Human Hepatitis B Virus Capsid Protein and Particles

(2010) Hung-Cheng Li et al.   PLoS Pathogens

Functional Surfaces of the Hepatitis B Virus Capsid

(2009) A. Pairan et al.   JOURNAL OF VIROLOGY

Testing the Balanced Electrostatic Interaction Hypothesis of Hepatitis B Virus DNA Synthesis by Using an In Vivo Charge Rebalance Approach

(2009) P. K. Chua et al.   JOURNAL OF VIROLOGY

Testing an Electrostatic Interaction Hypothesis of Hepatitis B Virus Capsid Stability by Using an In Vitro Capsid Disassembly/Reassembly System

(2009) M. Newman et al.   JOURNAL OF VIROLOGY

Separation and detection of large phosphoproteins using Phos-tag SDS-PAGE

(2009) Eiji Kinoshita et al.   Nature Protocols

Nuclear Entry of Hepatitis B Virus Capsids Involves Disintegration to Protein Dimers followed by Nuclear Reassociation to Capsids

(2009) Birgit Rabe et al.   PLoS Pathogens

Internal Core Protein Cleavage Leaves the Hepatitis B Virus Capsid Intact and Enhances Its Capacity for Surface Display of Heterologous Whole Chain Proteins

(2008) Andreas Walker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Six Classes of Nuclear Localization Signals Specific to Different Binding Grooves of Importin α

(2008) Shunichi Kosugi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatitis B viruses: Reverse transcription a different way

(2008) Michael Nassal   VIRUS RESEARCH