Stress Granule-Inducing Eukaryotic Translation Initiation Factor 4A Inhibitors Block Influenza A Virus Replication

The NS1 Protein from Influenza Virus Stimulates Translation Initiation by Enhancing Ribosome Recruitment to mRNAs

(2017) Baptiste Panthu et al.   JOURNAL OF MOLECULAR BIOLOGY

Influenza A Virus NS1 Protein Promotes Efficient Nuclear Export of Unspliced Viral M1 mRNA

(2017) Carina F. Pereira et al.   JOURNAL OF VIROLOGY

Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor

(2016) Shintaro Iwasaki et al.   NATURE

RNA binding specificity of Ebola virus transcription factor VP30

(2016) Julia Schlereth et al.   RNA Biology

The eIF4AIII RNA helicase is a critical determinant of human cytomegalovirus replication

(2016) Ben Ziehr et al.   VIROLOGY

Selective Degradation of Host RNA Polymerase II Transcripts by Influenza A Virus PA-X Host Shutoff Protein

(2016) Denys A. Khaperskyy et al.   PLoS Pathogens

A systematic view on influenza induced host shutoff

(2016) Adi Bercovich-Kinori et al.   eLife

Stress Granules Regulate Double-Stranded RNA-Dependent Protein Kinase Activation through a Complex Containing G3BP1 and Caprin1

(2015) Lucas C. Reineke et al.   mBio

Influenza Virus-Host Interactome Screen as a Platform for Antiviral Drug Development

(2014) Tokiko Watanabe et al.   Cell Host & Microbe

The Herpes Simplex Virus 2 Virion-Associated Ribonuclease vhs Interferes with Stress Granule Formation

(2014) R. L. Finnen et al.   JOURNAL OF VIROLOGY

Influenza A Virus-Induced Degradation of Eukaryotic Translation Initiation Factor 4B Contributes to Viral Replication by Suppressing IFITM3 Protein Expression

(2014) S. Wang et al.   JOURNAL OF VIROLOGY

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

Influenza A Virus Host Shutoff Disables Antiviral Stress-Induced Translation Arrest

(2014) Denys A. Khaperskyy et al.   PLoS Pathogens

Generation and characterization of a new panel of broadly reactive anti-NS1 mAbs for detection of influenza A virus

(2012) M. N. Rahim et al.   JOURNAL OF GENERAL VIROLOGY

Influenza Virus Induces Apoptosis via BAD-Mediated Mitochondrial Dysregulation

(2012) A. T. Tran et al.   JOURNAL OF VIROLOGY

Large G3BP-induced granules trigger eIF2α phosphorylation

(2012) Lucas C. Reineke et al.   MOLECULAR BIOLOGY OF THE CELL

Influenza A virus inhibits cytoplasmic stress granule formation

(2011) Denys A. Khaperskyy et al.   FASEB JOURNAL

Functional impairment of eIF4A and eIF4G factors correlates with inhibition of influenza virus mRNA translation

(2011) Emilio Yángüez et al.   VIROLOGY

Inhibitors of translation initiation as cancer therapeutics

(2009) Lisa Lindqvist et al.   Future Medicinal Chemistry

Lack of Bax Prevents Influenza A Virus-Induced Apoptosis and Causes Diminished Viral Replication

(2009) J. E. McLean et al.   JOURNAL OF VIROLOGY

Potent in vitro and in vivo anticancer activities of des-methyl, des-amino pateamine A, a synthetic analogue of marine natural product pateamine A

(2009) G. Kuznetsov et al.   MOLECULAR CANCER THERAPEUTICS

SUnSET, a nonradioactive method to monitor protein synthesis

(2009) Enrico K Schmidt et al.   NATURE METHODS

Antitumor Activity and Mechanism of Action of the Cyclopenta[b]benzofuran, Silvestrol

(2009) Regina Cencic et al.   PLoS One

Reprogramming mRNA translation during stress

(2008) Satoshi Yamasaki et al.   CURRENT OPINION IN CELL BIOLOGY

Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model

(2008) Marie-Eve Bordeleau et al.   JOURNAL OF CLINICAL INVESTIGATION