Proteome-scale relationships between local amino acid composition and protein fates and functions

Unification of Protein Abundance Datasets Yields a Quantitative Saccharomyces cerevisiae Proteome

(2018) Brandon Ho et al.   Cell Systems

TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics

(2017) Ian R. Mackenzie et al.   NEURON

Determinants and Regulation of Protein Turnover in Yeast

(2017) Miguel Martin-Perez et al.   Cell Systems

Absolute Quantification of Protein and mRNA Abundances Demonstrate Variability in Gene-Specific Translation Efficiency in Yeast

(2017) Petri-Jaan Lahtvee et al.   Cell Systems

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure

(2016) Saumya Jain et al.   CELL

Sequence Determinants of Intracellular Phase Separation by Complex Coacervation of a Disordered Protein

(2016) Chi W. Pak et al.   MOLECULAR CELL

Non-random distribution of homo-repeats: links with biological functions and human diseases

(2016) Michail Yu. Lobanov et al.   Scientific Reports

Deep Proteome Analysis Identifies Age-Related Processes in C. elegans

(2016) Vikram Narayan et al.   Cell Systems

Single Amino Acid Repeats in the Proteome World: Structural, Functional, and Evolutionary Insights

(2016) Amitha Sampath Kumar et al.   PLoS One

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

Relating sequence encoded information to form and function of intrinsically disordered proteins

(2015) Rahul K Das et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Key Role of Amino Acid Repeat Expansions in the Functional Diversification of Duplicated Transcription Factors

(2015) Núria Radó-Trilla et al.   MOLECULAR BIOLOGY AND EVOLUTION

Low complexity and disordered regions of proteins have different structural and amino acid preferences

(2015) Bandana Kumari et al.   Molecular BioSystems

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

(2015) Yuan Lin et al.   MOLECULAR CELL

Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles

(2015) Timothy J. Nott et al.   MOLECULAR CELL

Alternative Splicing in Next Generation Sequencing Data of Saccharomyces cerevisiae

(2015) Konrad Schreiber et al.   PLoS One

Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)

(2015) Matthias Altmeyer et al.   Nature Communications

Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules

(2015) Sonja Kroschwald et al.   eLife

Yeast prions and human prion-like proteins: sequence features and prediction methods

(2014) Sean M. Cascarina et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Global Proteome Turnover Analyses of the Yeasts S. cerevisiae and S. pombe

(2014) Romain Christiano et al.   Cell Reports

Intrinsically Disordered Segments Affect Protein Half-Life in the Cell and during Evolution

(2014) Robin van der Lee et al.   Cell Reports

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

(2013) Hong Joo Kim et al.   NATURE

Dissecting the role of low-complexity regions in the evolution of vertebrate proteins

(2012) Núria Radó-Trilla et al.   BMC EVOLUTIONARY BIOLOGY

The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease

(2012) Oliver D. King et al.   BRAIN RESEARCH

Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

(2012) Masato Kato et al.   CELL

Occurrence of six-amino-acid motifs in three eukaryotic proteomes

(2012) M. Yu. Lobanov et al.   MOLECULAR BIOLOGY

Evolutionary conservation of codon optimality reveals hidden signatures of cotranslational folding

(2012) Sebastian Pechmann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role of Low-Complexity Sequences in the Formation of Novel Protein Coding Sequences

(2011) M. Toll-Riera et al.   MOLECULAR BIOLOGY AND EVOLUTION

Occurrence of disordered patterns and homorepeats in eukaryotic and bacterial proteomes

(2011) M. Yu. Lobanov et al.   Molecular BioSystems

Disordered Patterns in Clustered Protein Data Bank and in Eukaryotic and Bacterial Proteomes

(2011) Michail Yu. Lobanov et al.   PLoS One

Low-complexity regions within protein sequences have position-dependent roles

(2010) Alain Coletta et al.   BMC Systems Biology

Biopython: freely available Python tools for computational molecular biology and bioinformatics

(2009) P. J. A. Cock et al.   BIOINFORMATICS

A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins

(2009) Simon Alberti et al.   CELL

Ab initio construction of a eukaryotic transcriptome by massively parallel mRNA sequencing

(2009) M. Yassour et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tandem and cryptic amino acid repeats accumulate in disordered regions of proteins

(2009) Michelle Simon et al.   GENOME BIOLOGY

P bodies promote stress granule assembly inSaccharomyces cerevisiae

(2008) J. Ross Buchan et al.   JOURNAL OF CELL BIOLOGY