Intellectual disability‐associated gene ftsj1 is responsible for 2′‐O‐methylation of specific tRNAs

tRNA 2′-O-methylation by a duo of TRM7/FTSJ1 proteins modulates small RNA silencing in Drosophila

(2020) Margarita T Angelova et al.   NUCLEIC ACIDS RESEARCH

FTSJ3 is an RNA 2′-O-methyltransferase recruited by HIV to avoid innate immune sensing

(2019) Mathieu Ringeard et al.   NATURE

Codon-Specific Translation by m1G37 Methylation of tRNA

(2019) Ya-Ming Hou et al.   Frontiers in Genetics

Multi-Substrate Specificity and the Evolutionary Basis for Interdependence in tRNA Editing and Methylation Enzymes

(2019) Sameer Dixit et al.   Frontiers in Genetics

Cooperative 2′-O-methylation of the wobble cytidine of human elongator tRNAMet(CAT) by a nucleolar and a Cajal body-specific box C/D RNP

(2019) Patrice Vitali et al.   GENES & DEVELOPMENT

5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs

(2019) Xin Chen et al.   NATURE CELL BIOLOGY

Mammalian NSUN2 introduces 5-methylcytidines into mitochondrial tRNAs

(2019) Saori Shinoda et al.   NUCLEIC ACIDS RESEARCH

Epigenetics comes to RNA

(2019) Ken Garber   SCIENCE

Nucleoporin Nup155 is part of the p53 network in liver cancer

(2019) Kerstin Holzer et al.   Nature Communications

Structure of tRNA methyltransferase complex of Trm7 and Trm734 reveals a novel binding interface for tRNA recognition

(2019) Akira Hirata et al.   NUCLEIC ACIDS RESEARCH

Modifications and functional genomics of human transfer RNA

(2018) Tao Pan   CELL RESEARCH

N 6 -Methyladenosines Modulate A-to-I RNA Editing

(2018) Jian-Feng Xiang et al.   MOLECULAR CELL

Selective terminal methylation of a tRNA wobble base

(2018) Isao Masuda et al.   NUCLEIC ACIDS RESEARCH

A rationale for tRNA modification circuits in the anticodon loop

(2018) Lu Han et al.   RNA

Lack of 2'-O-methylation in the tRNA anticodon loop of two phylogenetically distant yeast species activates the general amino acid control pathway

(2018) Lu Han et al.   PLoS Genetics

Editing and methylation at a single site by functionally interdependent activities

(2017) Mary Anne T. Rubio et al.   NATURE

ALKBH1 is an RNA dioxygenase responsible for cytoplasmic and mitochondrial tRNA modifications

(2017) Layla Kawarada et al.   NUCLEIC ACIDS RESEARCH

MODOMICS: a database of RNA modification pathways. 2017 update

(2017) Pietro Boccaletto et al.   NUCLEIC ACIDS RESEARCH

RNA modifications: what have we learned and where are we headed?

(2016) Michaela Frye et al.   NATURE REVIEWS GENETICS

Optimization of Codon Translation Rates via tRNA Modifications Maintains Proteome Integrity

(2015) Danny D. Nedialkova et al.   CELL

Defects in tRNA Anticodon Loop 2′-O-Methylation Are Implicated in Nonsyndromic X-Linked Intellectual Disability due to Mutations inFTSJ1

(2015) Michael P. Guy et al.   HUMAN MUTATION

Essentiality of threonylcarbamoyladenosine (t6A), a universal tRNA modification, in bacteria

(2015) Patrick C. Thiaville et al.   MOLECULAR MICROBIOLOGY

GtRNAdb 2.0: an expanded database of transfer RNA genes identified in complete and draft genomes

(2015) Patricia P. Chan et al.   NUCLEIC ACIDS RESEARCH

Dynamic modulation of Dnmt2-dependent tRNA methylation by the micronutrient queuine

(2015) Martin Müller et al.   NUCLEIC ACIDS RESEARCH

Identification of determinants for tRNA substrate recognition byEscherichia coliC/U34 2′-O-methyltransferase

(2015) Mi Zhou et al.   RNA Biology

Identification of Restriction Factors by Human Genome-Wide RNA Interference Screening of Viral Host Range Mutants Exemplified by Discovery of SAMD9 and WDR6 as Inhibitors of the Vaccinia Virus K1L − C7L − Mutant

(2015) Gilad Sivan et al.   mBio

Wybutosine biosynthesis: Structural and mechanistic overview

(2015) Phanélie Perche-Letuvée et al.   RNA Biology

Two-subunit enzymes involved in eukaryotic post-transcriptional tRNA modification

(2015) Michael P Guy et al.   RNA Biology

Conservation of an intricate circuit for crucial modifications of the tRNAPheanticodon loop in eukaryotes

(2014) Michael P. Guy et al.   RNA

Correction of a Genetic Disease in Mouse via Use of CRISPR-Cas9

(2013) Yuxuan Wu et al.   Cell Stem Cell

NSun2-Mediated Cytosine-5 Methylation of Vault Noncoding RNA Determines Its Processing into Regulatory Small RNAs

(2013) Shobbir Hussain et al.   Cell Reports

Biosynthesis and Function of Posttranscriptional Modifications of Transfer RNAs

(2012) Basma El Yacoubi et al.   Annual Review of Genetics

GENCODE: The reference human genome annotation for The ENCODE Project

(2012) J. Harrow et al.   GENOME RESEARCH

In vivo identification of essential nucleotides in tRNA Leu to its functions by using a constructed yeast tRNA Leu knockout strain

(2012) Qian Huang et al.   NUCLEIC ACIDS RESEARCH

Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop

(2012) M. P. Guy et al.   RNA

Probing Protein-Protein Interactions with a Genetically Encoded Photo-crosslinking Amino Acid

(2011) Hui-wang Ai et al.   CHEMBIOCHEM

Q8IYL2 is a candidate gene for the familial epilepsy syndrome of Partial Epilepsy with Pericentral Spikes (PEPS)

(2011) Guy D. Leschziner et al.   EPILEPSY RESEARCH

A genetically incorporated crosslinker reveals chaperone cooperation in acid resistance

(2011) Meng Zhang et al.   Nature Chemical Biology

Grand Challenge Commentary: RNA epigenetics?

(2010) Chuan He   Nature Chemical Biology

Photocrosslinkers illuminate interactions in living cells

(2008) Yoshihito Tanaka et al.   Molecular BioSystems