tRNA 2′-O-methylation by a duo of TRM7/FTSJ1 proteins modulates small RNA silencing in Drosophila

FTSJ3 is an RNA 2′-O-methyltransferase recruited by HIV to avoid innate immune sensing

(2019) Mathieu Ringeard et al.   NATURE

RNA 2’-O-Methylation (Nm) Modification in Human Diseases

(2019) Dilyana G. Dimitrova et al.   Genes

Cooperative 2′-O-methylation of the wobble cytidine of human elongator tRNAMet(CAT) by a nucleolar and a Cajal body-specific box C/D RNP

(2019) Patrice Vitali et al.   GENES & DEVELOPMENT

Modification of messenger RNA by 2′-O-methylation regulates gene expression in vivo

(2019) Brittany A. Elliott et al.   Nature Communications

Time-resolved NMR monitoring of tRNA maturation

(2019) Pierre Barraud et al.   Nature Communications

The Gypsy Endogenous Retrovirus Drives Non-Cell-Autonomous Propagation in a Drosophila TDP-43 Model of Neurodegeneration

(2019) Yung-Heng Chang et al.   CURRENT BIOLOGY

2′-O-methylation in mRNA disrupts tRNA decoding during translation elongation

(2018) Junhong Choi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Queuosine modification protects cognate tRNAs against ribonuclease cleavage

(2018) Xiaoyun Wang et al.   RNA

2′-O-methylation in mRNA disrupts tRNA decoding during translation elongation

(2018) Junhong Choi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mutations in Cytosine-5 tRNA Methyltransferases Impact Mobile Element Expression and Genome Stability at Specific DNA Repeats

(2018) Bianca Genenncher et al.   Cell Reports

Lack of 2'-O-methylation in the tRNA anticodon loop of two phylogenetically distant yeast species activates the general amino acid control pathway

(2018) Lu Han et al.   PLoS Genetics

The role of RNA modifications in the regulation of tRNA cleavage

(2018) Shawn M. Lyons et al.   FEBS LETTERS

Human host-range restriction of the vaccinia virus C7/K1 double deletion mutant is mediated by an atypical mode of translation inhibition

(2018) Gilad Sivan et al.   JOURNAL OF VIROLOGY

RNA ribose methylation (2′-O-methylation): Occurrence, biosynthesis and biological functions

(2018) Lilia Ayadi et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

A mouse model for intellectual disability caused by mutations in the X-linked 2′‑O‑methyltransferase Ftsj1 gene

(2018) Lars R. Jensen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Co-chaperone Hsp70/Hsp90-organizing protein (Hop) is required for transposon silencing and Piwi-interacting RNA (piRNA) biogenesis

(2017) Joseph A. Karam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptome-wide Analysis of Roles for tRNA Modifications in Translational Regulation

(2017) Hsin-Jung Chou et al.   MOLECULAR CELL

ALKBH1 is an RNA dioxygenase responsible for cytoplasmic and mitochondrial tRNA modifications

(2017) Layla Kawarada et al.   NUCLEIC ACIDS RESEARCH

MODOMICS: a database of RNA modification pathways. 2017 update

(2017) Pietro Boccaletto et al.   NUCLEIC ACIDS RESEARCH

tRNA-derived small RNAs target transposable element transcripts

(2017) German Martinez et al.   NUCLEIC ACIDS RESEARCH

Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS

(2017) Lisa Krug et al.   PLoS Genetics

Illumina-based RiboMethSeq approach for mapping of 2′-O-Me residues in RNA

(2016) Virginie Marchand et al.   NUCLEIC ACIDS RESEARCH

Assembly and trafficking of box C/D and H/ACA snoRNPs

(2016) Séverine Massenet et al.   RNA Biology

RNA modification in Cajal bodies

(2016) U. Thomas Meier   RNA Biology

Endogenous tRNA-Derived Fragments Suppress Breast Cancer Progression via YBX1 Displacement

(2015) Hani Goodarzi et al.   CELL

Defects in tRNA Anticodon Loop 2′-O-Methylation Are Implicated in Nonsyndromic X-Linked Intellectual Disability due to Mutations inFTSJ1

(2015) Michael P. Guy et al.   HUMAN MUTATION

Orchestrating high-throughput genomic analysis with Bioconductor

(2015) Wolfgang Huber et al.   NATURE METHODS

Nucleotide modifications within bacterial messenger RNAs regulate their translation and are able to rewire the genetic code

(2015) Thomas Philipp Hoernes et al.   NUCLEIC ACIDS RESEARCH

The Cricket Paralysis Virus Suppressor Inhibits microRNA Silencing Mediated by the Drosophila Argonaute-2 Protein

(2015) Corinne Besnard-Guérin et al.   PLoS One

Two-subunit enzymes involved in eukaryotic post-transcriptional tRNA modification

(2015) Michael P Guy et al.   RNA Biology

RNA methyltransferases involved in 5′ cap biosynthesis

(2015) Magdalena Byszewska et al.   RNA Biology

Understanding the Effect of Locked Nucleic Acid and 2′-O-Methyl Modification on the Hybridization Thermodynamics of a miRNA–mRNA Pair in the Presence and Absence of AfPiwi Protein

(2014) Santosh Kumar et al.   BIOCHEMISTRY

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies

(2014) Alexandros Stamatakis   BIOINFORMATICS

Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders

(2014) S. Blanco et al.   EMBO JOURNAL

tRNA fragments in human health and disease

(2014) Paul Anderson et al.   FEBS LETTERS

Interplay of LNA and 2′-O-Methyl RNA in the Structure and Thermodynamics of RNA Hybrid Systems: A Molecular Dynamics Study Using the Revised AMBER Force Field and Comparison with Experimental Results

(2014) Ilyas Yildirim et al.   JOURNAL OF PHYSICAL CHEMISTRY B

G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments

(2014) Pavel Ivanov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of two homologous 2′-O-methyltransferases showing different specificities for their tRNA substrates

(2014) Jonathan Somme et al.   RNA

Conservation of an intricate circuit for crucial modifications of the tRNAPheanticodon loop in eukaryotes

(2014) Michael P. Guy et al.   RNA

Efficient CRISPR/Cas9 Plasmids for Rapid and Versatile Genome Editing in Drosophila

(2014) Joseph Gokcezade et al.   G3-Genes Genomes Genetics

tRNA modifications: Necessary for correct tRNA-derived fragments during the recovery from stress?

(2013) Zeljko Durdevic et al.   BIOESSAYS

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

The Genetic Makeup of the Drosophila piRNA Pathway

(2013) Dominik Handler et al.   MOLECULAR CELL

Activation of transposable elements during aging and neuronal decline in Drosophila

(2013) Wanhe Li et al.   NATURE NEUROSCIENCE

AutomiG, a Biosensor to Detect Alterations in miRNA Biogenesis and in Small RNA Silencing Guided by Perfect Target Complementarity

(2013) Clément Carré et al.   PLoS One

The RNA Methyltransferase Dnmt2 Is Required for Efficient Dicer-2-Dependent siRNA Pathway Activity in Drosophila

(2013) Zeljko Durdevic et al.   Cell Reports

Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing

(2013) Shivendra Kishore et al.   GENOME BIOLOGY

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Genome-wide Identification and Quantitative Analysis of Cleaved tRNA Fragments Induced by Cellular Stress

(2012) Mridusmita Saikia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Tetrahymena Piwi Bound to Mature tRNA 3′ Fragments Activates the Exonuclease Xrn2 for RNA Processing in the Nucleus

(2012) Mary T. Couvillion et al.   MOLECULAR CELL

BC1-FMRP interaction is modulated by 2′-O-methylation: RNA-binding activity of the tudor domain and translational regulation at synapses

(2012) Caroline Lacoux et al.   NUCLEIC ACIDS RESEARCH

Mechanisms that impact microRNA stability in plants

(2012) Yuanyuan Zhao et al.   RNA Biology

Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop

(2012) M. P. Guy et al.   RNA

Human GTPases Associate with RNA Polymerase II To Mediate Its Nuclear Import

(2011) C. Carre et al.   MOLECULAR AND CELLULAR BIOLOGY

Angiogenin-Induced tRNA Fragments Inhibit Translation Initiation

(2011) Pavel Ivanov et al.   MOLECULAR CELL

Biogenesis and function of nuclear bodies

(2011) Yuntao S. Mao et al.   TRENDS IN GENETICS

An in vivo RNAi assay identifies major genetic and cellular requirements for primary piRNA biogenesis in Drosophila

(2010) Daniel Olivieri et al.   EMBO JOURNAL

Hsc70/Hsp90 Chaperone Machinery Mediates ATP-Dependent RISC Loading of Small RNA Duplexes

(2010) Shintaro Iwasaki et al.   MOLECULAR CELL

trimAl: a tool for automated alignment trimming in large-scale phylogenetic analyses

(2009) S. Capella-Gutierrez et al.   BIOINFORMATICS

The steroid hormone receptor EcR finely modulates Drosophila lifespan during adulthood in a sex-specific manner

(2009) Hervé Tricoire et al.   MECHANISMS OF AGEING AND DEVELOPMENT

2'-O-methylation stabilizes Piwi-associated small RNAs and ensures DNA elimination in Tetrahymena

(2009) H. M. Kurth et al.   RNA

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

The post-transcriptional steps of eukaryotic ribosome biogenesis

(2008) A. K. Henras et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Chromatin-Associated Genes Protect the Yeast Genome From Ty1 Insertional Mutagenesis

(2008) Katherine M. Nyswaner et al.   GENETICS

Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster

(2008) Katsutomo Okamura et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Exploring TAR–RNA aptamer loop–loop interaction by X-ray crystallography, UV spectroscopy and surface plasmon resonance

(2008) Isabelle Lebars et al.   NUCLEIC ACIDS RESEARCH

Cocoa confers life span extension in Drosophila melanogaster

(2008) Sepehr Bahadorani et al.   NUTRITION RESEARCH