Non-Melanoma Skin Cancer: news from microbiota research

Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab

(2020) N. Chaput et al.   ANNALS OF ONCOLOGY

苏金单抗持续用于治疗银屑病的疗效

(2020) M. Augustin et al.   BRITISH JOURNAL OF DERMATOLOGY

The impact of NBUVB on microbial community profiling in the lesional skin of vitiligo subjects

(2020) Xiangfeng Yuan et al.   MICROBIAL PATHOGENESIS

How Probiotics Affect the Microbiota

(2020) Grégoire Wieërs et al.   Frontiers in Cellular and Infection Microbiology

Molecular Profiling of Keratinocyte Skin Tumors Links Staphylococcus aureus Overabundance and Increased Human β-Defensin-2 Expression to Growth Promotion of Squamous Cell Carcinoma

(2020) Nandhitha Madhusudhan et al.   Cancers

Modulating the microbiome to improve therapeutic response in cancer

(2019) Jennifer L McQuade et al.   LANCET ONCOLOGY

An Emerging Issue in Oncogenic Virology: the Role of Beta Human Papillomavirus Types in the Development of Cutaneous Squamous Cell Carcinoma

(2019) Dana E. Rollison et al.   JOURNAL OF VIROLOGY

Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5−/− mice

(2019) Yan Li et al.   Nature Communications

The impact of skin care products on skin chemistry and microbiome dynamics

(2019) Amina Bouslimani et al.   BMC BIOLOGY

Oral administration of lipoteichoic acid from Lactobacillus rhamnosus GG overcomes UVB‐induced immunosuppression and impairs skin tumor growth in mice

(2019) Adrián D. Friedrich et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Identification of Risk Factors for Multiple Non-Melanoma Skin Cancers in Italian Kidney Transplant Recipients

(2019) Elisa Zavattaro et al.   Medicina-Lithuania

Potential Role of the Microbiome in Acne: A Comprehensive Review

(2019) Lee et al.   Journal of Clinical Medicine

Targeting the gut‐skin axis—Probiotics as new tools for skin disorder management?

(2019) Magdolna Szántó et al.   EXPERIMENTAL DERMATOLOGY

The role of topical probiotics on skin conditions: A systematic review of animal and human studies and implications for future therapies

(2019) Rebecca Knackstedt et al.   EXPERIMENTAL DERMATOLOGY

Butyric Acid from Probiotic Staphylococcus epidermidis in the Skin Microbiome Down-Regulates the Ultraviolet-Induced Pro-Inflammatory IL-6 Cytokine via Short-Chain Fatty Acid Receptor

(2019) Sunita Keshari et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Immune adjuvant therapy using Bacillus Calmette–Guérin cell wall skeleton (BCG-CWS) in advanced malignancies

(2019) Sumiyuki Nishida et al.   MEDICINE

Papillomavirus Immune Evasion Strategies Target the Infected Cell and the Local Immune System

(2019) Chenhao Zhou et al.   Frontiers in Oncology

Concomitant medications during immune checkpoint blockage in cancer patients: Novel insights in this emerging clinical scenario

(2019) Giovanni Rossi et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Safety review of phenoxyethanol when used as a preservative in cosmetics

(2019) B. Dréno et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Immunity to commensal papillomaviruses protects against skin cancer

(2019) John D. Strickley et al.   NATURE

Skin Exposure to Narrow Band Ultraviolet (UVB) Light Modulates the Human Intestinal Microbiome

(2019) Else S. Bosman et al.   Frontiers in Microbiology

Skin Cancer Following Solid Organ Transplantation: A Review of Risk Factors and Models of Care

(2018) Matthew D. Howard et al.   AMERICAN JOURNAL OF CLINICAL DERMATOLOGY

The role of the microbiome in psoriasis: moving from disease description to treatment selection?

(2018) E.A. Langan et al.   BRITISH JOURNAL OF DERMATOLOGY

Immunotherapy in head and neck cancers: A new challenge for immunologists, pathologists and clinicians

(2018) Sophie Outh-Gauer et al.   CANCER TREATMENT REVIEWS

The microbiome in dermatology

(2018) Shenara Musthaq et al.   CLINICS IN DERMATOLOGY

Production and rearing of germ-free X-SCID pigs

(2018) Hiromasa Hara et al.   EXPERIMENTAL ANIMALS

Skin microbiota and human 3D skin models

(2018) Franziska Rademacher et al.   EXPERIMENTAL DERMATOLOGY

3D skin models for 3R research: The potential of 3D reconstructed skin models to study skin barrier function

(2018) Hanna Niehues et al.   EXPERIMENTAL DERMATOLOGY

Skin Commensal Malassezia globosa Secreted Protease Attenuates Staphylococcus aureus Biofilm Formation

(2018) Hao Li et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The human skin microbiome

(2018) Allyson L. Byrd et al.   NATURE REVIEWS MICROBIOLOGY

Non-melanoma skin cancer as a possible adverse event due to anti-interleukin-6 treatment

(2018) JEF Diernaes et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients

(2018) Vyara Matson et al.   SCIENCE

The gut microbiota and immune checkpoint inhibitors

(2018) Audrey Humphries et al.   Human Vaccines & Immunotherapeutics

Beta HPV38 oncoproteins act with a hit-and-run mechanism in ultraviolet radiation-induced skin carcinogenesis in mice

(2018) Daniele Viarisio et al.   PLoS Pathogens

A commensal strain of Staphylococcus epidermidis protects against skin neoplasia

(2018) Teruaki Nakatsuji et al.   Science Advances

Epstein–Barr Virus and Human Papillomaviruses Interactions and Their Roles in the Initiation of Epithelial–Mesenchymal Transition and Cancer Progression

(2018) Farhan S. Cyprian et al.   Frontiers in Oncology

Skin cancer healthcare impact: A nation-wide assessment of an administrative database

(2018) A.F. Duarte et al.   Cancer Epidemiology

Prognostic Factors for Checkpoint Inhibitor Based Immunotherapy: An Update With New Evidences

(2018) Xinyu Yan et al.   Frontiers in Pharmacology

Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization

(2018) Hsin-Wen Chang et al.   Microbiome

Melanoma-related changes in skin microbiome

(2018) Jakub Mrázek et al.   FOLIA MICROBIOLOGICA

Skin microbiota’s community effort

(2018) Emily Sohn   NATURE

Human papillomavirus type 16 E6 and E7 oncoproteins interact with the nuclear p53-binding protein 1 in an in vitro reconstructed 3D epithelium: new insights for the virus-induced DNA damage response

(2018) Diletta Francesca Squarzanti et al.   Virology Journal

Diosgenin promotes antitumor immunity and PD-1 antibody efficacy against melanoma by regulating intestinal microbiota

(2018) Mengxue Dong et al.   Cell Death & Disease

Innate antimicrobial immunity in the skin: A protective barrier against bacteria, viruses, and fungi

(2018) Margaret Coates et al.   PLoS Pathogens

Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year

(2017) Elizabeth A. Kennedy et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Human Skin Is the Largest Epithelial Surface for Interaction with Microbes

(2017) Richard L. Gallo   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The BRAF Inhibitor Vemurafenib Enhances UV-Induced Skin Carcinogenesis in Beta HPV38 E6 and E7 Transgenic Mice

(2017) Daniele Viarisio et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Skin Immune Landscape: Inside and Outside the Organism

(2017) Florence Abdallah et al.   MEDIATORS OF INFLAMMATION

The skin microbiome and immune system: Potential target for chemoprevention?

(2017) Mohammad Asif Sherwani et al.   PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE

Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

(2017) V. Gopalakrishnan et al.   SCIENCE

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

(2017) Bertrand Routy et al.   SCIENCE

Microbiota dysbiosis in select human cancers: Evidence of association and causality

(2017) Jie Chen et al.   SEMINARS IN IMMUNOLOGY

HER-2/Epstein-Barr virus crosstalk in human gastric carcinogenesis: A novel concept of oncogene/oncovirus interaction

(2017) Farhan S. Cyprian et al.   Cell Adhesion & Migration

Cancer risk in patients with candidiasis: a nationwide population-based cohort study

(2017) Li-Min Chung et al.   Oncotarget

Endogenous Antimicrobial Peptide Expression in Response to Bacterial Epidermal Colonization

(2017) Michael Brandwein et al.   Frontiers in Immunology

The gut-skin axis in health and disease: A paradigm with therapeutic implications

(2016) Catherine A. O'Neill et al.   BIOESSAYS

Skin Biomes

(2016) N. Fyhrquist et al.   CURRENT ALLERGY AND ASTHMA REPORTS

The epithelial–mesenchymal transition (EMT) is regulated by oncoviruses in cancer

(2016) Xue Chen et al.   FASEB JOURNAL

Increased Bacterial Load and Expression of Antimicrobial Peptides in Skin of Barrier-Deficient Mice with Reduced Cancer Susceptibility

(2016) Ken Natsuga et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Microbiome in healthy skin, update for dermatologists

(2016) B. Dréno et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Microbial Ecology of the Human Skin

(2016) Anthony M. Cundell   MICROBIAL ECOLOGY

Prevention of ultraviolet radiation-induced immunosuppression by sunscreen in Candida albicans-induced delayed-type hypersensitivity

(2016) QUAN CHEN et al.   Molecular Medicine Reports

Topographical and physiological differences of the skin mycobiome in health and disease

(2016) Jay-Hyun Jo et al.   Virulence

Developments in Intralesional Therapy for Metastatic Melanoma

(2016) Sarah Sloot et al.   Cancer Control

The skin microbiome: Associations between altered microbial communities and disease

(2015) Laura S Weyrich et al.   AUSTRALASIAN JOURNAL OF DERMATOLOGY

How informative is the mouse for human gut microbiota research?

(2015) T. L. A. Nguyen et al.   Disease Models & Mechanisms

Recurrent antibiotic exposure may promote cancer formation – Another step in understanding the role of the human microbiota?

(2015) Ben Boursi et al.   EUROPEAN JOURNAL OF CANCER

Systemic associations of hidradenitis suppurativa

(2015) John J. Kohorst et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy

(2015) A. Sivan et al.   SCIENCE

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

(2015) M. Vetizou et al.   SCIENCE

Innate sensing of microbial products promotes wound-induced skin cancer

(2015) Esther Hoste et al.   Nature Communications

EBV-driven LMP1 and IFN-γ up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy

(2015) Wenfeng Fang et al.   Oncotarget

Human Papillomavirus Community in Healthy Persons, Defined by Metagenomics Analysis of Human Microbiome Project Shotgun Sequencing Data Sets

(2014) Y. Ma et al.   JOURNAL OF VIROLOGY

Standardised animal models of host microbial mutualism

(2014) A J Macpherson et al.   Mucosal Immunology

Modeling Cutaneous Squamous Carcinoma Development in the Mouse

(2014) P. Y. Huang et al.   Cold Spring Harbor Perspectives in Medicine

The Skin Microbiome: A Focus on Pathogens and Their Association with Skin Disease

(2014) Keisha Findley et al.   PLoS Pathogens

Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility

(2014) Sara Cipolat et al.   eLife

Role of the skin microbiome in atopic dermatitis

(2014) Alexander Salava et al.   Clinical and Translational Allergy

Fermented Prunus mume with Probiotics Inhibits 7,12-Dimethylbenz[a]anthracene and 12-O-Tetradecanoyl phorbol-13-acetate Induced Skin Carcinogenesis through Alleviation of Oxidative Stress

(2013) Jin-A Lee et al.   Asian Pacific Journal of Cancer Prevention

Emerging roles of the microbiome in cancer

(2013) S. J. Bultman   CARCINOGENESIS

Health Effects of Probiotics on the Skin

(2013) M. Rahmati Roudsari et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Microbiome and skin diseases

(2013) Patrick L.J.M. Zeeuwen et al.   Current Opinion in Allergy and Clinical Immunology

Tissue-engineered skin substitutes: an overview

(2013) Enrico Catalano et al.   JOURNAL OF ARTIFICIAL ORGANS

Non-melanoma skin cancer: carcinogenesis and chemoprevention

(2013) Andrew C. Chen et al.   PATHOLOGY

Occupational Exposure to Ultraviolet Radiation and Risk of Non-Melanoma Skin Cancer in a Multinational European Study

(2013) Simona Surdu et al.   PLoS One

Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment

(2013) N. Iida et al.   SCIENCE

Functions of the skin microbiota in health and disease

(2013) James A. Sanford et al.   SEMINARS IN IMMUNOLOGY

The microbiome extends to subepidermal compartments of normal skin

(2013) Teruaki Nakatsuji et al.   Nature Communications

A systematic review of worldwide incidence of nonmelanoma skin cancer

(2012) A. Lomas et al.   BRITISH JOURNAL OF DERMATOLOGY

Lipoteichoic acid from Lactobacillus rhamnosus GG as an oral photoprotective agent against UV-induced carcinogenesis

(2012) Federico S. Weill et al.   BRITISH JOURNAL OF NUTRITION

Global burden of cancers attributable to infections in 2008: a review and synthetic analysis

(2012) Catherine de Martel et al.   LANCET ONCOLOGY

Genomic approaches to studying the human microbiota

(2012) George M. Weinstock   NATURE

Photodynamic Antifungal Chemotherapy†

(2012) Piergiacomo Calzavara-Pinton et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

The Response of Human Skin Commensal Bacteria as a Reflection of UV Radiation: UV-B Decreases Porphyrin Production

(2012) Yanhan Wang et al.   PLoS One

Characterization of beta papillomavirus E4 expression in tumours from Epidermodysplasia Verruciformis patients and in experimental models

(2012) Cinzia Borgogna et al.   VIROLOGY

Microbiome dynamics of human epidermis following skin barrier disruption

(2012) Patrick LJM Zeeuwen et al.   GENOME BIOLOGY

Microbial deprivation, inflammation and cancer

(2011) Leena C. von Hertzen et al.   CANCER AND METASTASIS REVIEWS

Pre- and Probiotics for Human Skin

(2011) Jean Krutmann   CLINICS IN PLASTIC SURGERY

Re-inventing intratumoral immunotherapy for melanoma

(2011) Pierre L Triozzi et al.   Immunotherapy

Metabolic activities and probiotic potential of bifidobacteria

(2011) D.A. Russell et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

The Coordinated Response of the Physical and Antimicrobial Peptide Barriers of the Skin

(2011) Andrew W. Borkowski et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Microbial Symbiosis with the Innate Immune Defense System of the Skin

(2011) Richard L. Gallo et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Could Malassezia yeasts be implicated in skin carcinogenesis through the production of aryl-hydrocarbon receptor ligands?

(2011) G. Gaitanis et al.   MEDICAL HYPOTHESES

The skin microbiome

(2011) Elizabeth A. Grice et al.   NATURE REVIEWS MICROBIOLOGY

Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice

(2011) A. L. Goodman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

E6 and E7 from Beta Hpv38 Cooperate with Ultraviolet Light in the Development of Actinic Keratosis-Like Lesions and Squamous Cell Carcinoma in Mice

(2011) Daniele Viarisio et al.   PLoS Pathogens

Clinical evidence of benefits of a dietary supplement containing probiotic and carotenoids on ultraviolet-induced skin damage

(2010) D. Bouilly-Gauthier et al.   BRITISH JOURNAL OF DERMATOLOGY

Therapeutical use of probiotic formulations in clinical practice

(2010) T. Iannitti et al.   CLINICAL NUTRITION

Is there a ‘gut-brain-skin axis’?

(2010) Petra Arck et al.   EXPERIMENTAL DERMATOLOGY

Skin Commensals Amplify the Innate Immune Response to Pathogens by Activation of Distinct Signaling Pathways

(2010) Ines Wanke et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Chronic bacterial and parasitic infections and cancer: a review

(2010) Matthew E Falagas et al.   Journal of Infection in Developing Countries

Staphylococcus aureus and Squamous Cell Carcinoma of the Skin

(2009) J. Kullander et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Selective Antimicrobial Action Is Provided by Phenol-Soluble Modulins Derived from Staphylococcus epidermidis, a Normal Resident of the Skin

(2009) Anna L. Cogen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Commensal bacteria regulate Toll-like receptor 3–dependent inflammation after skin injury

(2009) Yuping Lai et al.   NATURE MEDICINE

Multi-stage chemical carcinogenesis in mouse skin: Fundamentals and applications

(2009) Erika L Abel et al.   Nature Protocols

Topographical and Temporal Diversity of the Human Skin Microbiome

(2009) E. A. Grice et al.   SCIENCE

Bacterial Community Variation in Human Body Habitats Across Space and Time

(2009) E. K. Costello et al.   SCIENCE

The epithelial–mesenchymal transition induced by keratinocyte growth conditions is overcome by E6 and E7 from HPV16, but not HPV8 and HPV38: Characterization of global transcription profiles

(2009) Barbara Azzimonti et al.   VIROLOGY

A diversity profile of the human skin microbiota

(2008) E. A. Grice et al.   GENOME RESEARCH

Altered expression of UVB-induced cytokines in human papillomavirus-immortalized epithelial cells

(2008) V. Dell'Oste et al.   JOURNAL OF GENERAL VIROLOGY