UPR modulation of host immunity by Pseudomonas aeruginosa in cystic fibrosis

Endoplasmic Reticulum Stress Impaired Uncoupling Protein 1 Expression via the Suppression of Peroxisome Proliferator-Activated Receptor γ Binding Activity in Mice Beige Adipocytes

(2019) Ana Yuliana et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation

(2019) Samuel Lara-Reyna et al.   Frontiers in Immunology

Endoplasmic reticulum stress and mitochondrial biogenesis are potential therapeutic targets for abdominal aortic aneurysm

(2019) Masashi Miyao et al.   CLINICAL SCIENCE

Pseudomonas aeruginosa Induced Host Epithelial Cell Mitochondrial Dysfunction

(2019) Nicholas M. Maurice et al.   Scientific Reports

PPARγ Regulates Mitochondrial Structure and Function and Human Pulmonary Artery Smooth Muscle Cell Proliferation

(2018) Samantha M. Yeligar et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Mixed Communities of Mucoid and Nonmucoid Pseudomonas aeruginosa Exhibit Enhanced Resistance to Host Antimicrobials

(2018) Sankalp Malhotra et al.   mBio

Inhibition of the ER stress IRE1α inflammatory pathway protects against cell death in mitochondrial complex I mutant cells

(2018) Meghan S. Soustek et al.   Cell Death & Disease

Modulation of the unfolded protein response pathway as an antiviral approach in airway epithelial cells

(2018) Aline Schögler et al.   ANTIVIRAL RESEARCH

Peroxisome proliferator-activated receptor-γ agonists attenuate biofilm formation by Pseudomonas aeruginosa

(2017) Brahmchetna Bedi et al.   FASEB JOURNAL

Endoplasmic reticulum-mitochondrial crosstalk: a novel role for the mitochondrial peptide humanin

(2017) DavidR Hinton et al.   Neural Regeneration Research

Endoplasmic Reticulum Stress-Induced CHOP Inhibits PGC-1α and Causes Mitochondrial Dysfunction in Diabetic Embryopathy

(2017) Xi Chen et al.   TOXICOLOGICAL SCIENCES

TREM-1-accentuated lung injury via miR-155 is inhibited by LP17 nanomedicine

(2016) Zhihong Yuan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The coming of age of the mitochondria–ER contact: a matter of thickness

(2016) M Giacomello et al.   CELL DEATH AND DIFFERENTIATION

Hypoxia and sterile inflammation in cystic fibrosis airways: mechanisms and potential therapies

(2016) Samuel T. Montgomery et al.   EUROPEAN RESPIRATORY JOURNAL

The Natural Occurring Compounds Targeting Endoplasmic Reticulum Stress

(2016) Hai Liu et al.   Evidence-based Complementary and Alternative Medicine

PPARγ as a therapeutic target to rescue mitochondrial function in neurological disease

(2016) Juan Carlos Corona et al.   FREE RADICAL BIOLOGY AND MEDICINE

Enhanced Clearance of Pseudomonas aeruginosa by Peroxisome Proliferator-Activated Receptor Gamma

(2016) Brahmchetna Bedi et al.   INFECTION AND IMMUNITY

Protein misfolding in the endoplasmic reticulum as a conduit to human disease

(2016) Miao Wang et al.   NATURE

Regulation of claudin/zonula occludens-1 complexes by hetero-claudin interactions

(2016) Barbara Schlingmann et al.   Nature Communications

X-Box–Binding Protein 1 and Innate Immune Responses of Human Cystic Fibrosis Alveolar Macrophages

(2015) Bob A. Lubamba et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The peroxisome proliferator-activated receptors in cardiovascular diseases: experimental benefits and clinical challenges

(2015) Wai San Cheang et al.   BRITISH JOURNAL OF PHARMACOLOGY

PPARγand the Innate Immune System Mediate the Resolution of Inflammation

(2015) Amanda Croasdell et al.   PPAR Research

Cationic Peptides Facilitate Iron-induced Mutagenesis in Bacteria

(2015) Alexandro Rodríguez-Rojas et al.   PLoS Genetics

Virulence Factors of Pseudomonas aeruginosa Induce Both the Unfolded Protein and Integrated Stress Responses in Airway Epithelial Cells

(2015) Emily F. A. van ‘t Wout et al.   PLoS Pathogens

Endoplasmic Reticulum Stress and Oxidative Stress in Cell Fate Decision and Human Disease

(2014) Stewart Siyan Cao et al.   ANTIOXIDANTS & REDOX SIGNALING

IL-13 Attenuates Gastrointestinal Candidiasis in Normal and Immunodeficient RAG-2-/- Mice via Peroxisome Proliferator-Activated Receptor-  Activation

(2014) A. Coste et al.   JOURNAL OF IMMUNOLOGY

Neisseria gonorrhoeae Modulates Iron-Limiting Innate Immune Defenses in Macrophages

(2014) Susu M. Zughaier et al.   PLoS One

Nicotine Stimulates Nerve Growth Factor in Lung Fibroblasts through an NFκB-Dependent Mechanism

(2014) Cherry Wongtrakool et al.   PLoS One

Cationic Antimicrobial Peptides Promote Microbial Mutagenesis and Pathoadaptation in Chronic Infections

(2014) Dominique H. Limoli et al.   PLoS Pathogens

The endoplasmic reticulum–mitochondria connection: One touch, multiple functions

(2013) Saverio Marchi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

(2013) Jaeseok Han et al.   NATURE CELL BIOLOGY

PPARγ signaling and metabolism: the good, the bad and the future

(2013) Maryam Ahmadian et al.   NATURE MEDICINE

Airway inflammation in cystic fibrosis: molecular mechanisms and clinical implications

(2013) Malena Cohen-Cymberknoh et al.   THORAX

Targeting the Peroxisome Proliferator-Activated Receptor-γ to Counter the Inflammatory Milieu in Obesity

(2013) Cesar Corzo et al.   Diabetes & Metabolism Journal

Atypical Activation of the Unfolded Protein Response in Cystic Fibrosis Airway Cells Contributes to p38 MAPK-Mediated Innate Immune Responses

(2012) C. J. Blohmke et al.   JOURNAL OF IMMUNOLOGY

Systemic Analysis of PPAR  in Mouse Macrophage Populations Reveals Marked Diversity in Expression with Critical Roles in Resolution of Inflammation and Airway Immunity

(2012) E. L. Gautier et al.   JOURNAL OF IMMUNOLOGY

Expression of PPARγ and Paraoxonase 2 Correlated with Pseudomonas aeruginosa Infection in Cystic Fibrosis

(2012) Phoebe E. Griffin et al.   PLoS One

PPARγ as a therapeutic target in cystic fibrosis

(2012) Johanna F. Dekkers et al.   TRENDS IN MOLECULAR MEDICINE

ER stress-induced inflammation: does it aid or impede disease progression?

(2012) Abhishek D. Garg et al.   TRENDS IN MOLECULAR MEDICINE

PPARγas a Potential Target to Treat Airway Mucus Hypersecretion in Chronic Airway Inflammatory Diseases

(2012) Yongchun Shen et al.   PPAR Research

ROCK Inhibitor and Feeder Cells Induce the Conditional Reprogramming of Epithelial Cells

(2011) Xuefeng Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

Antimicrobial peptides: key components of the innate immune system

(2011) Mukesh Pasupuleti et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics

(2011) Roberto Bravo et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Evolution of pulmonary inflammation and nutritional status in infants and young children with cystic fibrosis

(2011) S. C. Ranganathan et al.   THORAX

CFTR: folding, misfolding and correcting the ΔF508 conformational defect

(2011) Gergely L. Lukacs et al.   TRENDS IN MOLECULAR MEDICINE

Paraoxonase 2 Deficiency Alters Mitochondrial Function and Exacerbates the Development of Atherosclerosis

(2010) Asokan Devarajan et al.   ANTIOXIDANTS & REDOX SIGNALING

Endoplasmic Reticulum Stress-activated C/EBP Homologous Protein Enhances Nuclear Factor-κB Signals via Repression of Peroxisome Proliferator-activated Receptor γ

(2010) Seong-Hwan Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Repression of Peroxisome Proliferator-Activated Receptor   by Mucosal Ribotoxic Insult-Activated CCAAT/Enhancer-Binding Protein Homologous Protein

(2010) S.-H. Park et al.   JOURNAL OF IMMUNOLOGY

TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages

(2010) Fabio Martinon et al.   NATURE IMMUNOLOGY

Pharmacological correction of a defect in PPAR-γ signaling ameliorates disease severity in Cftr-deficient mice

(2010) Gregory S Harmon et al.   NATURE MEDICINE

The Identification of Markers of Macrophage Differentiation in PMA-Stimulated THP-1 Cells and Monocyte-Derived Macrophages

(2010) Marc Daigneault et al.   PLoS One

Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon

(2010) L. Peyrin-Biroulet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ΔF508 CFTR processing correction and activity in polarized airway and non-airway cell monolayers

(2010) S.M. Rowe et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Airway Epithelial Inflammation-induced Endoplasmic Reticulum Ca2+Store Expansion Is Mediated by X-box Binding Protein-1

(2009) Mary E. B. Martino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxisome proliferator-activated receptor-γ in cystic fibrosis lung epithelium

(2008) Aura Perez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Fat and Beyond: The Diverse Biology of PPARγ

(2008) Peter Tontonoz et al.   Annual Review of Biochemistry

Role of PPAR-gamma in the Modulation of CD36 and FcgammaRII induced by LDL with Low and High Degrees of Oxidation During the Differentiation of the Monocytic THP-1 Cell Line

(2008) Francisco J.O. Rios et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Airway epithelial cell inflammatory signalling in cystic fibrosis

(2008) Jacky Jacquot et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY