Inhibition of the ER stress IRE1α inflammatory pathway protects against cell death in mitochondrial complex I mutant cells

A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation

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Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis

(2016) Hyo Kyun Chung et al.   JOURNAL OF CELL BIOLOGY

Bromodomain Inhibitors Correct Bioenergetic Deficiency Caused by Mitochondrial Disease Complex I Mutations

(2016) Joeva J. Barrow et al.   MOLECULAR CELL

Mitofusin-mediated ER stress triggers neurodegeneration in pink1/parkin models of Parkinson’s disease

(2016) I Celardo et al.   Cell Death & Disease

Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency

(2016) Johannes K. Ehinger et al.   Nature Communications

Prevalence of nuclear and mitochondrial DNA mutations related to adult mitochondrial disease

(2015) Gráinne S. Gorman et al.   ANNALS OF NEUROLOGY

Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage

(2015) Denise N. Bronner et al.   IMMUNITY

GDF15 is a novel biomarker to evaluate efficacy of pyruvate therapy for mitochondrial diseases

(2015) Yasunori Fujita et al.   MITOCHONDRION

Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and dynamics

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Coenzyme Q10 as a therapy for mitochondrial disease

(2014) I.P. Hargreaves   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Glucose deprivation induces reticulum stress by the PERK pathway and caspase-7- and calpain-mediated caspase-12 activation

(2013) Selene García de la Cadena et al.   APOPTOSIS

Mitochondria: In Sickness and in Health

(2012) Jodi Nunnari et al.   CELL

Reactive oxygen species-induced activation of ERK and p38 MAPK mediates PMA-induced NETs release from human neutrophils

(2012) Ravi S. Keshari et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The mitochondrial KATP channel—Fact or fiction?

(2012) Keith D. Garlid et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Assessment of mitochondrial respiratory chain enzymatic activities on tissues and cultured cells

(2012) Marco Spinazzi et al.   Nature Protocols

Understanding mitochondrial complex I assembly in health and disease

(2011) Masakazu Mimaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

(2011) Ariel C. Bulua et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis

(2010) Vishal M Gohil et al.   NATURE BIOTECHNOLOGY

Interaction of mitochondrial potassium channels with the permeability transition pore

(2009) Yu Cheng et al.   FEBS LETTERS

An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen

(2009) Benoît Kornmann et al.   SCIENCE

From endoplasmic-reticulum stress to the inflammatory response

(2008) Kezhong Zhang et al.   NATURE