Generation of a novel CD30 + B cell subset producing GM‐CSF and its possible link to the pathogenesis of systemic sclerosis

Circulating follicular helper T cells are increased in systemic sclerosis and promote plasmablast differentiation through the IL-21 pathway which can be inhibited by ruxolitinib

(2019) Laure Ricard et al.   ANNALS OF THE RHEUMATIC DISEASES

Interleukin-4 and interleukin-13 as possible therapeutic targets in systemic sclerosis

(2019) Giulia Gasparini et al.   CYTOKINE

Dendritic cells in systemic sclerosis: Advances from human and mice studies

(2018) Alsya J. Affandi et al.   IMMUNOLOGY LETTERS

Distinct Properties of Human M-CSF and GM-CSF Monocyte-Derived Macrophages to Simulate Pathological Lung Conditions In Vitro: Application to Systemic and Inflammatory Disorders with Pulmonary Involvement

(2018) Alain Lescoat et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

T follicular helper–like cells contribute to skin fibrosis

(2018) Devon K. Taylor et al.   Science Translational Medicine

Association of Defective Regulation of Autoreactive Interleukin-6-Producing Transitional B Lymphocytes With Disease in Patients With Systemic Sclerosis

(2018) Taher E. Taher et al.   Arthritis & Rheumatology

Tuning the Cytokine Responses: An Update on Interleukin (IL)-4 and IL-13 Receptor Complexes

(2018) Ilkka S. Junttila   Frontiers in Immunology

Identification of Novel STAT6-Regulated Proteins in Mouse B Cells by Comparative Transcriptome and Proteome Analysis

(2017) Lavanya Mokada-Gopal et al.   JOURNAL OF IMMUNOLOGY

Defective IL-10-producing Breg cells

(2017) Dario Ummarino   Nature Reviews Rheumatology

A multicenter, open-label, comparative study of B-cell depletion therapy with Rituximab for systemic sclerosis-associated interstitial lung disease

(2017) Dimitrios Daoussis et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

T follicular helper and T H 2 cells in allergic responses

(2017) Masato Kubo   ALLERGOLOGY INTERNATIONAL

Scleroderma Peripheral B Lymphocytes Secrete Interleukin-6 and Transforming Growth Factor β and Activate Fibroblasts

(2017) Nicolas Dumoitier et al.   Arthritis & Rheumatology

CD11b+Gr-1dim Tolerogenic Dendritic Cell-Like Cells Are Expanded in Interstitial Lung Disease in SKG Mice

(2017) Sho Sendo et al.   Arthritis & Rheumatology

IL-22, GM-CSF and IL-17 in peripheral CD4+ T cell subpopulations during multiple sclerosis relapses and remission. Impact of corticosteroid therapy

(2017) Nathalie Muls et al.   PLoS One

Evolution of serum cytokine profile after hematopoietic stem cell transplantation in systemic sclerosis patients

(2016) L Michel et al.   BONE MARROW TRANSPLANTATION

Myeloid cell populations and fibrogenic parameters in bleomycin- and HOCl-induced fibrosis

(2016) Verena K. Raker et al.   EXPERIMENTAL DERMATOLOGY

GM-CSF: From Growth Factor to Central Mediator of Tissue Inflammation

(2016) Burkhard Becher et al.   IMMUNITY

Human Circulating T Follicular Helper Cell Subsets in Health and Disease

(2016) Hideki Ueno   JOURNAL OF CLINICAL IMMUNOLOGY

Breg Cells Are Numerically Decreased and Functionally Impaired in Patients With Systemic Sclerosis

(2016) Athanasios Mavropoulos et al.   Arthritis & Rheumatology

Synovial CD4+ T-cell-derived GM-CSF supports the differentiation of an inflammatory dendritic cell population in rheumatoid arthritis

(2015) G Reynolds et al.   ANNALS OF THE RHEUMATIC DISEASES

The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity

(2015) Andrew L. Croxford et al.   IMMUNITY

Immunogenetics of systemic sclerosis: Defining heritability, functional variants and shared-autoimmunity pathways

(2015) Lara Bossini-Castillo et al.   JOURNAL OF AUTOIMMUNITY

Proinflammatory GM-CSF–producing B cells in multiple sclerosis and B cell depletion therapy

(2015) Rui Li et al.   Science Translational Medicine

CD1a+ survivin+ dendritic cell infiltration in dermal lesions of systemic sclerosis

(2015) Sho Mokuda et al.   ARTHRITIS RESEARCH & THERAPY

Complementary action of granulocyte macrophage colony-stimulating factor and interleukin-17A induces interleukin-23, receptor activator of nuclear factor-κB ligand, and matrix metalloproteinases and drives bone and cartilage pathology in experimental arthritis: rationale for combination therapy in rheumatoid arthritis

(2015) Annemarie E. M. van Nieuwenhuijze et al.   ARTHRITIS RESEARCH & THERAPY

Effects and safety of rituximab in systemic sclerosis: an analysis from the European Scleroderma Trial and Research (EUSTAR) group

(2014) Suzana Jordan et al.   ANNALS OF THE RHEUMATIC DISEASES

GM-CSF but Not IL-17 Is Critical for the Development of Severe Interstitial Lung Disease in SKG Mice

(2014) Aoi Shiomi et al.   JOURNAL OF IMMUNOLOGY

Regulatory B10 Cells Are Decreased in Patients With Rheumatoid Arthritis and Are Inversely Correlated With Disease Activity

(2014) Claire I. Daien et al.   Arthritis & Rheumatology

Rituximab dissociates the tight link between disease activity and joint damage in rheumatoid arthritis patients

(2012) Daniel Aletaha et al.   ANNALS OF THE RHEUMATIC DISEASES

Placebo-Controlled Trial of Tofacitinib Monotherapy in Rheumatoid Arthritis

(2012) Roy Fleischmann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Differentiation Potential of CD14+ Monocytes into Myofibroblasts in Patients with Systemic Sclerosis

(2012) Nadine Binai et al.   PLoS One

The Pathogenesis of Systemic Sclerosis

(2011) Tamiko R. Katsumoto et al.   Annual Review of Pathology-Mechanisms of Disease

Characterization of a Transitional Preplasmablast Population in the Process of Human B Cell to Plasma Cell Differentiation

(2011) Michel Jourdan et al.   JOURNAL OF IMMUNOLOGY

Safety and efficacy of rituximab in systemic lupus erythematosus: Results from 136 patients from the French autoimmunity and rituximab registry

(2010) Benjamin Terrier et al.   ARTHRITIS AND RHEUMATISM

Memory B and memory plasma cells

(2010) Taketoshi Yoshida et al.   IMMUNOLOGICAL REVIEWS

B cell depletion with rituximab in patients with diffuse cutaneous systemic sclerosis

(2009) Robert Lafyatis et al.   ARTHRITIS AND RHEUMATISM