Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity
Authors
Keywords
-
Journal
NATURE IMMUNOLOGY
Volume 14, Issue 12, Pages 1247-1255
Publisher
Springer Nature America, Inc
Online
2013-11-04
DOI
10.1038/ni.2749
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Dependency of Caspase-1 Activation Induced in Macrophages by Listeria monocytogenes on Cytolysin, Listeriolysin O, after Evasion from Phagosome into the Cytoplasm
- (2014) H. Hara et al. JOURNAL OF IMMUNOLOGY
- Phosphorylation of NLRC4 is critical for inflammasome activation
- (2012) Yan Qu et al. NATURE
- Novel role of PKR in inflammasome activation and HMGB1 release
- (2012) Ben Lu et al. NATURE
- The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases
- (2011) Beckley K. Davis et al. Annual Review of Immunology
- IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection
- (2011) Nagaraj Kerur et al. Cell Host & Microbe
- Critical role for NLRP3 in necrotic death triggered by Mycobacterium tuberculosis
- (2011) Ka-Wing Wong et al. CELLULAR MICROBIOLOGY
- Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation
- (2011) Greta Guarda et al. IMMUNITY
- Critical Roles of ASC Inflammasomes in Caspase-1 Activation and Host Innate Resistance to Streptococcus pneumoniae Infection
- (2011) R. Fang et al. JOURNAL OF IMMUNOLOGY
- The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
- (2011) Bolormaa Vandanmagsar et al. NATURE MEDICINE
- Tumor suppressor death-associated protein kinase is required for full IL-1 production
- (2010) Y.-T. Chuang et al. BLOOD
- Inflammasomes as microbial sensors
- (2010) Luigi Franchi et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome
- (2010) Sarah Kim et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis
- (2010) Md. Hasan Zaki et al. IMMUNITY
- Enhanced T cell-independent antibody responses in c-Jun N-terminal kinase 2 (JNK2)-deficient B cells following stimulation with CpG-1826 and anti-IgM
- (2010) Yanling Cao et al. IMMUNOLOGY LETTERS
- Involvement of Absent in Melanoma 2 in Inflammasome Activation in Macrophages Infected with Listeria monocytogenes
- (2010) K. Tsuchiya et al. JOURNAL OF IMMUNOLOGY
- (1,3)- -Glucans Activate Both Dectin-1 and NLRP3 Inflammasome in Human Macrophages
- (2010) P. Kankkunen et al. JOURNAL OF IMMUNOLOGY
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
- (2010) Peter Duewell et al. NATURE
- The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
- (2010) Vijay A K Rathinam et al. NATURE IMMUNOLOGY
- The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
- (2010) Teresa Fernandes-Alnemri et al. NATURE IMMUNOLOGY
- Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
- (2010) E. A. Miao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Inflammasomes: Guardians of the Body
- (2009) Fabio Martinon et al. Annual Review of Immunology
- Immunological and Inflammatory Functions of the Interleukin-1 Family
- (2009) Charles A. Dinarello Annual Review of Immunology
- Caspases and Kinases in a Death Grip
- (2009) Manabu Kurokawa et al. CELL
- Asc and Ipaf Inflammasomes Direct Distinct Pathways for Caspase-1 Activation in Response to Legionella pneumophila
- (2009) C. L. Case et al. INFECTION AND IMMUNITY
- Activation of Inflammasomes Requires Intracellular Redistribution of the Apoptotic Speck-Like Protein Containing a Caspase Recruitment Domain
- (2009) N. B. Bryan et al. JOURNAL OF IMMUNOLOGY
- Calcium-Independent Phospholipase A2β Is Dispensable in Inflammasome Activation and Its Inhibition by Bromoenol Lactone
- (2009) Luigi Franchi et al. Journal of Innate Immunity
- Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
- (2009) Olaf Gross et al. NATURE
- Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport
- (2009) Hidetaka Kosako et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- NLR-mediated control of inflammasome assembly in the host response against bacterial pathogens
- (2009) Igor E. Brodsky et al. SEMINARS IN IMMUNOLOGY
- Malarial Hemozoin Activates the NLRP3 Inflammasome through Lyn and Syk Kinases
- (2009) Marina Tiemi Shio et al. PLoS Pathogens
- Expression of ASC in Renal Tissues of Familial Mediterranean Fever Patients with Amyloidosis: Postulating a Role for ASC in AA Type Amyloid Deposition
- (2008) Banu Balci-Peynircioglu et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Common variants in the NLRP3 region contribute to Crohn's disease susceptibility
- (2008) Alexandra-Chloé Villani et al. NATURE GENETICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started