CRISPR with a Happy Ending: Non‐Templated DNA Repair for Prokaryotic Genome Engineering

Bacterial NHEJ: a never ending story

(2019) Claire Bertrand et al.   MOLECULAR MICROBIOLOGY

Bioeconomy for sustainable development

(2019) Alfredo Aguilar et al.   Biotechnology Journal

A matter of background: DNA repair pathways as a possible cause for the sparse distribution of CRISPR-Cas systems in bacteria

(2019) Aude Bernheim et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Transposon-encoded CRISPR–Cas systems direct RNA-guided DNA integration

(2019) Sanne E. Klompe et al.   NATURE

RNA-guided DNA insertion with CRISPR-associated transposases

(2019) Jonathan Strecker et al.   SCIENCE

Search-and-replace genome editing without double-strand breaks or donor DNA

(2019) Andrew V. Anzalone et al.   NATURE

Harnessing type I CRISPR–Cas systems for genome engineering in human cells

(2019) Peter Cameron et al.   NATURE BIOTECHNOLOGY

Editor's cut: DNA cleavage by CRISPR RNA-guided nucleases Cas9 and Cas12a

(2019) Thomas Swartjes et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants

(2019) Kira S. Makarova et al.   NATURE REVIEWS MICROBIOLOGY

Hijacking CRISPR-Cas for high-throughput bacterial metabolic engineering: advances and prospects

(2018) Ioannis Mougiakos et al.   CURRENT OPINION IN BIOTECHNOLOGY

Functional Genomics via CRISPR–Cas

(2018) Kyle Ford et al.   JOURNAL OF MOLECULAR BIOLOGY

Genome editing by natural and engineered CRISPR-associated nucleases

(2018) Wen Y. Wu et al.   Nature Chemical Biology

CRISPR-Cpf1-Assisted Multiplex Genome Editing and Transcriptional Repression in Streptomyces

(2018) Lei Li et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A CRISPR-Cpf1-Assisted Non-Homologous End Joining Genome Editing System of Mycobacterium smegmatis

(2018) Bingbing Sun et al.   Biotechnology Journal

CRISPR/Cpf1 facilitated large fragment deletion in Saccharomyces cerevisiae

(2018) Zhen-Hai Li et al.   JOURNAL OF BASIC MICROBIOLOGY

Stress-inducible NHEJ in bacteria: function in DNA repair and acquisition of heterologous DNA

(2018) Pierre Dupuy et al.   NUCLEIC ACIDS RESEARCH

Phage Mu Gam protein promotes NHEJ in concert with Escherichia coli ligase

(2018) Sudipta Bhattacharyya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbial Cell Factories for the Production of Terpenoid Flavor and Fragrance Compounds

(2017) Florence M. Schempp et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

High-Throughput Approaches to Pinpoint Function within the Noncoding Genome

(2017) Antonino Montalbano et al.   MOLECULAR CELL

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

(2017) Nicole M. Gaudelli et al.   NATURE

Non-homologous DNA end joining and alternative pathways to double-strand break repair

(2017) Howard H. Y. Chang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cas9-mediated genome editing in the methanogenic archaeonMethanosarcina acetivorans

(2017) Dipti D. Nayak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterizing a thermostable Cas9 for bacterial genome editing and silencing

(2017) Ioannis Mougiakos et al.   Nature Communications

Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria

(2017) Aude Bernheim et al.   Nature Communications

A thermostable Cas9 with increased lifetime in human plasma

(2017) Lucas B. Harrington et al.   Nature Communications

The quest for the minimal bacterial genome

(2016) Esteban Martínez-García et al.   CURRENT OPINION IN BIOTECHNOLOGY

Consequences of Cas9 cleavage in the chromosome ofEscherichia coli

(2016) Lun Cui et al.   NUCLEIC ACIDS RESEARCH

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

(2016) Omar O. Abudayyeh et al.   SCIENCE

A CRISPR-Cas9 Assisted Non-Homologous End-Joining Strategy for One-step Engineering of Bacterial Genome

(2016) Tianyuan Su et al.   Scientific Reports

Engineering biological systems toward a sustainable bioeconomy

(2015) Mateus Schreiner Garcez Lopes   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

CRISPR-Cas9 Based Engineering of Actinomycetal Genomes

(2015) Yaojun Tong et al.   ACS Synthetic Biology

Targeted Large-Scale Deletion of Bacterial Genomes Using CRISPR-Nickases

(2015) Kylie Standage-Beier et al.   ACS Synthetic Biology

Microhomology-based choice of Cas9 nuclease target sites

(2014) Sangsu Bae et al.   NATURE METHODS

Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects

(2014) Bin Shen et al.   NATURE METHODS

Resistance of Bacillus subtilis Spore DNA to Lethal Ionizing Radiation Damage Relies Primarily on Spore Core Components and DNA Repair, with Minor Effects of Oxygen Radical Detoxification

(2013) Ralf Moeller et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

(2013) Luke A. Gilbert et al.   CELL

Green and sustainable manufacture of chemicals from biomass: state of the art

(2013) Roger A. Sheldon   GREEN CHEMISTRY

High-level semi-synthetic production of the potent antimalarial artemisinin

(2013) C. J. Paddon et al.   NATURE

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

(2013) Wenyan Jiang et al.   NATURE BIOTECHNOLOGY

Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system

(2013) David Bikard et al.   NUCLEIC ACIDS RESEARCH

Ribonucleolytic resection is required for repair of strand displaced nonhomologous end-joining intermediates

(2013) E. J. Bartlett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytotoxic Chromosomal Targeting by CRISPR/Cas Systems Can Reshape Bacterial Genomes and Expel or Remodel Pathogenicity Islands

(2013) Reuben B. Vercoe et al.   PLoS Genetics

Construction of microbial cell factories for industrial bioprocesses

(2012) Michael Sauer et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Microbial engineering for the production of advanced biofuels

(2012) Pamela P. Peralta-Yahya et al.   NATURE

Bacterial DNA repair: recent insights into the mechanism of RecBCD, AddAB and AdnAB

(2012) Dale B. Wigley   NATURE REVIEWS MICROBIOLOGY

Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol

(2011) Harry Yim et al.   Nature Chemical Biology

TAL Effectors: Customizable Proteins for DNA Targeting

(2011) A. J. Bogdanove et al.   SCIENCE

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA

(2010) Josiane E. Garneau et al.   NATURE

Genome editing with engineered zinc finger nucleases

(2010) Fyodor D. Urnov et al.   NATURE REVIEWS GENETICS

Structure of bacterial LigD 3'-phosphoesterase unveils a DNA repair superfamily

(2010) P. A. Nair et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An end-joining repair mechanism in Escherichia coli

(2010) R. Chayot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CRISPR/Cas, the Immune System of Bacteria and Archaea

(2010) P. Horvath et al.   SCIENCE

Repairing DNA double-strand breaks by the prokaryotic non-homologous end-joining pathway

(2009) Nigel C. Brissett et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Recombineering: a homologous recombination-based method of genetic engineering

(2009) Shyam K Sharan et al.   Nature Protocols

The pathways and outcomes of mycobacterial NHEJ depend on the structure of the broken DNA ends

(2008) J. Aniukwu et al.   GENES & DEVELOPMENT

Small CRISPR RNAs Guide Antiviral Defense in Prokaryotes

(2008) S. J. J. Brouns et al.   SCIENCE

Genetic elements for selection, deletion mutagenesis and complementation inFrancisellaspp.

(2007) Jagjit S. Ludu et al.   FEMS MICROBIOLOGY LETTERS