Reduction of senescence‐associated beta‐galactosidase activity by vitamin E in human fibroblasts depends on subjects’ age and cell passage number

High doses of synthetic antioxidants induce premature senescence in cultivated mesenchymal stem cells

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Emerging roles of extracellular vesicles in cellular senescence and aging

(2018) Masaki Takasugi   AGING CELL

oxLDL-mediated cellular senescence is associated with increased NADPH oxidase p47phox recruitment to caveolae

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CD36 initiates the secretory phenotype during the establishment of cellular senescence

(2018) Mengyang Chong et al.   EMBO REPORTS

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Vitamin E: Regulatory Role on Signal Transduction

(2018) Jean-Marc Zingg   IUBMB LIFE

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(2018) Sarah DeWeerdt   NATURE

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(2017) Alexey Golubev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Tocopheryl Phosphate Induces VEGF Expression via CD36/PI3Kγ in THP-1 Monocytes

(2017) Jean-Marc Zingg et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Regulation of lipids is central to replicative senescence

(2017) Darleny Y. Lizardo et al.   Molecular BioSystems

Replication stress-induced endogenous DNA damage drives cellular senescence induced by a sub-lethal oxidative stress

(2017) Gireedhar Venkatachalam et al.   NUCLEIC ACIDS RESEARCH

Effects of bioactive compounds on senescence and components of senescence associated secretory phenotypes in vitro

(2017) Janubová Mária et al.   Food & Function

Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells

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Modulation of cAMP levels by high-fat diet and curcumin and regulatory effects on CD36/FAT scavenger receptor/fatty acids transporter gene expression

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(2016) Henry Jay Forman   FREE RADICAL BIOLOGY AND MEDICINE

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Beneficial effects of omega-3 and vitamin E coadministration on gene expression of SIRT1 and PGC1α and serum antioxidant enzymes in patients with coronary artery disease

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Senescent intimal foam cells are deleterious at all stages of atherosclerosis

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Sub-lethal oxidative stress induces lysosome biogenesis via a lysosomal membrane permeabilization-cathepsin-caspase 3-transcription factor EB-dependent pathway

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Vitamin E: A Role in Signal Transduction

(2015) Jean-Marc Zingg   Annual Review of Nutrition

Foam cell-derived 4-hydroxynonenal induces endothelial cell senescence in a TXNIP-dependent manner

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Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

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Vitamin E Supplementation Delays Cellular SenescenceIn Vitro

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Long-term vitamin E supplementation reduces atherosclerosis and mortality in Ldlr−/− mice, but not when fed Western style diet

(2014) Mohsen Meydani et al.   ATHEROSCLEROSIS

Vitamin E supplementation and lifespan in model organisms

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Inhibition of Mitochondrial CytochromecRelease and Suppression of Caspases by Gamma-Tocotrienol Prevent Apoptosis and Delay Aging in Stress-Induced Premature Senescence of Skin Fibroblasts

(2012) Suzana Makpol et al.   Oxidative Medicine and Cellular Longevity

Redox control of cell proliferation

(2012) Joyce Chiu et al.   TRENDS IN CELL BIOLOGY

The redox stress hypothesis of aging

(2011) Rajindar S. Sohal et al.   FREE RADICAL BIOLOGY AND MEDICINE

Vitamin E, signalosomes and gene expression in T cells

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Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

Effect of tocopheryl phosphate on key biomarkers of inflammation: Implication in the reduction of atherosclerosis progression in a hypercholesterolaemic rabbit model

(2010) Roksan Libinaki et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Modulation of gene expression by α-tocopherol and α-tocopheryl phosphate in THP-1 monocytes

(2010) Jean-Marc Zingg et al.   FREE RADICAL BIOLOGY AND MEDICINE

Vitamin E supplementation and mammalian lifespan

(2010) Ruth Banks et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Gene-Regulatory Activity of α-Tocopherol

(2010) Gerald Rimbach et al.   MOLECULES

The Role of Phytonutrients in Skin Health

(2010) Julie A. Evans et al.   Nutrients

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

(2009) Florence Debacq-Chainiaux et al.   Nature Protocols

Cardioprotection with α-tocopheryl phosphate: Amelioration of myocardial ischemia reperfusion injury is linked with its ability to generate a survival signal through Akt activation

(2008) Subhendu Mukherjee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis

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