Metabolomics reveals an essential role for peroxisome proliferator-activated receptor α in bile acid homeostasis

Proximal Tubular Secretion of Creatinine by Organic Cation Transporter OCT2 in Cancer Patients

(2012) G. Ciarimboli et al.   CLINICAL CANCER RESEARCH

Disruption of phospholipid and bile acid homeostasis in mice with nonalcoholic steatohepatitis

(2012) Naoki Tanaka et al.   HEPATOLOGY

A comprehensive understanding of thioTEPA metabolism in the mouse using UPLC–ESI-QTOFMS-based metabolomics

(2011) Fei Li et al.   BIOCHEMICAL PHARMACOLOGY

Lithocholic acid disrupts phospholipid and sphingolipid homeostasis leading to cholestasis in mice

(2011) Tsutomu Matsubara et al.   HEPATOLOGY

Metabolomics Reveals Attenuation of the SLC6A20 Kidney Transporter in Nonhuman Primate and Mouse Models of Type 2 Diabetes Mellitus

(2011) Andrew D. Patterson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Untargeted Metabolomics Identifies Enterobiome Metabolites and Putative Uremic Toxins as Substrates of Organic Anion Transporter 1 (Oat1)

(2011) William R. Wikoff et al.   JOURNAL OF PROTEOME RESEARCH

Dose-Response of Five Bile Acids on Serum and Liver Bile Acid Concentrations and Hepatotoxicty in Mice

(2011) Peizhen Song et al.   TOXICOLOGICAL SCIENCES

Comparative metabolism of cyclophosphamide and ifosfamide in the mouse using UPLC–ESI-QTOFMS-based metabolomics

(2010) Fei Li et al.   BIOCHEMICAL PHARMACOLOGY

Metabolomics Identifies Novel Hnf1α-Dependent Physiological Pathwaysin Vivo

(2010) Jessica A. Bonzo et al.   MOLECULAR ENDOCRINOLOGY

Gene Knockout and Metabolome Analysis of Carnitine/Organic Cation Transporter OCTN1

(2010) Yukio Kato et al.   PHARMACEUTICAL RESEARCH

Serum Metabolomics Reveals Irreversible Inhibition of Fatty Acid β-Oxidation through the Suppression of PPARα Activation as a Contributing Mechanism of Acetaminophen-Induced Hepatotoxicity

(2009) Chi Chen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Control of Steroid 21-oic Acid Synthesis by Peroxisome Proliferator-activated Receptor α and Role of the Hypothalamic-Pituitary-Adrenal Axis

(2009) Ting Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of Fibrate Drugs on Expression of ABCA1 and HDL Biogenesis in Hepatocytes

(2009) Mohammad Anwar Hossain et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Urinary metabolomics in Fxr-null mice reveals activated adaptive metabolic pathways upon bile acid challenge

(2009) Joo-Youn Cho et al.   JOURNAL OF LIPID RESEARCH

Human Urinary Metabolomic Profile of PPARα Induced Fatty Acid β-Oxidation

(2009) Andrew D. Patterson et al.   JOURNAL OF PROTEOME RESEARCH

A metabonomic study of hepatitis B-induced liver cirrhosis and hepatocellular carcinoma by using RP-LC and HILIC coupled with mass spectrometry

(2009) Peiyuan Yin et al.   Molecular BioSystems

Critical Role of PPAR-α in Perfluorooctanoic Acid– and Perfluorodecanoic Acid–Induced Downregulation of Oatp Uptake Transporters in Mouse Livers

(2008) Xingguo Cheng et al.   TOXICOLOGICAL SCIENCES

Hepatoprotective role of PXR activation and MRP3 in cholic acid-induced cholestasis

(2007) S Teng et al.   BRITISH JOURNAL OF PHARMACOLOGY