Diverse Functions of Polyamines in Virus Infection

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation

(2019) Daniel J. Puleston et al.   Cell Metabolism

Polyamine depletion inhibits bunyavirus infection via generation of noninfectious interfering virions

(2019) Vincent Mastrodomenico et al.   JOURNAL OF VIROLOGY

Coxsackievirus B3 Responds to Polyamine Depletion via Enhancement of 2A and 3C Protease Activity

(2019) Courtney N. Dial et al.   Viruses-Basel

Polyamine depletion abrogates enterovirus cellular attachment

(2019) Thomas M. Kicmal et al.   JOURNAL OF VIROLOGY

Ribavirin Induces Polyamine Depletion via Nucleotide Depletion to Limit Virus Replication

(2019) Patrick M. Tate et al.   Cell Reports

Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence

(2019) Hanlin Zhang et al.   MOLECULAR CELL

Polyamine Metabolism and Oxidative Protein Folding in the ER as ROS-Producing Systems Neglected in Virology

(2018) Olga Smirnova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Interferons: Reprogramming the Metabolic Network against Viral Infection

(2018) Kavita Raniga et al.   Viruses-Basel

Differential Mechanisms for the Involvement of Polyamines and Hypusinated eIF5A in Ebola Virus Gene Expression

(2018) Michelle E. Olsen et al.   JOURNAL OF VIROLOGY

Difluoromethylornithine in cancer: new advances

(2017) George A Alexiou et al.   Future Oncology

Low-molecular-weight regulators of biogenic polyamine metabolism affect cytokine production and expression of hepatitis С virus proteins in Huh7.5 human hepatocarcinoma cells

(2017) O. V. Masalova et al.   MOLECULAR BIOLOGY

Biosynthesis of polyamines and polyamine-containing molecules

(2016) A. J. Michael   BIOCHEMICAL JOURNAL

Interferon-Induced Spermidine-Spermine Acetyltransferase and Polyamine Depletion Restrict Zika and Chikungunya Viruses

(2016) Bryan C. Mounce et al.   Cell Host & Microbe

Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses

(2016) Bryan C. Mounce et al.   JOURNAL OF VIROLOGY

Activation ofSAT1engages polyamine metabolism with p53-mediated ferroptotic responses

(2016) Yang Ou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication

(2016) Michelle E. Olsen et al.   mBio

Remaining Mysteries of Molecular Biology: The Role of Polyamines in the Cell

(2015) Leonor Miller-Fleming et al.   JOURNAL OF MOLECULAR BIOLOGY

Novel gammaherpesvirus functions encoded by bovine herpesvirus 6 (bovine lymphotropic virus)

(2014) J. Jia et al.   JOURNAL OF GENERAL VIROLOGY

Phase 1 study of N 1,N 11-diethylnorspermine (DENSPM) in patients with advanced hepatocellular carcinoma

(2013) Lipika Goyal et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Downregulation of the polyamine regulator spermidine/spermine N1-acetyltransferase by Epstein–Barr virus in a Burkitt's lymphoma cell line

(2013) Mingxia Shi et al.   VIRUS RESEARCH

Unbiased Metabolite Profiling Indicates That a Diminished Thymidine Pool Is the Underlying Mechanism of Colon Cancer Chemoprevention by Alpha-Difluoromethylornithine

(2013) M. Witherspoon et al.   Cancer Discovery

Biogenic polyamines spermine and spermidine activate RNA polymerase and inhibit RNA helicase of hepatitis C virus

(2012) A. N. Korovina et al.   BIOCHEMISTRY-MOSCOW

Evidence that AMP-activated protein kinase can negatively modulate Ornithine decarboxylase activity in cardiac myoblasts

(2012) Catherine L. Passariello et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Paramecium bursariaChlorella Virus 1 Encodes a Polyamine Acetyltransferase

(2012) Zachary Charlop-Powers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HSV Infection Induces Production of ROS, which Potentiate Signaling from Pattern Recognition Receptors: Role for S-glutathionylation of TRAF3 and 6

(2011) Regina Gonzalez-Dosal et al.   PLoS Pathogens

Hepatocyte NAD(P)H oxidases as an endogenous source of reactive oxygen species during hepatitis C virus infection

(2010) Nabora Soledad Reyes de Mochel et al.   HEPATOLOGY

Hepatitis C virus induces oxidative stress, DNA damage and modulates the DNA repair enzyme NEIL1

(2010) Sampa Pal et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Elevated polyamines induce c-MYC overexpression by perturbing quadruplex–WC duplex equilibrium

(2009) Niti Kumar et al.   NUCLEIC ACIDS RESEARCH

Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A

(2009) Mainul Hoque et al.   Retrovirology

Spermidine/spermine-N1-acetyltransferase: a key metabolic regulator

(2008) Anthony E. Pegg   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Polyamines modulate the subcellular localization of RNA-binding protein HuR through AMP-activated protein kinase-regulated phosphorylation and acetylation of importin α1

(2008) Tongtong Zou et al.   BIOCHEMICAL JOURNAL

ODC1 Is a Critical Determinant of MYCN Oncogenesis and a Therapeutic Target in Neuroblastoma

(2008) M. D. Hogarty et al.   CANCER RESEARCH

Epstein-Barr Virus Nuclear Antigen 3C Interacts with and Enhances the Stability of the c-Myc Oncoprotein

(2008) B. G. Bajaj et al.   JOURNAL OF VIROLOGY