Exosomes from Human Adipose Tissue-Derived Mesenchymal Stem Cells Promote Epidermal Barrier Repair by Inducing de Novo Synthesis of Ceramides in Atopic Dermatitis

Advances in Analysis of Biodistribution of Exosomes by Molecular Imaging

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Fatty acid transport protein 4 is required for incorporation of saturated ultralong-chain fatty acids into epidermal ceramides and monoacylglycerols

(2019) Meei-Hua Lin et al.   Scientific Reports

Cellular and Metabolic Basis for the Ichthyotic Phenotype in NIPAL4 (Ichthyin)–Deficient Canines

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Mesenchymal stromal cell exosome–enhanced regulatory T-cell production through an antigen-presenting cell–mediated pathway

(2018) Bin Zhang et al.   CYTOTHERAPY

Exosomes derived from human adipose tissue-derived mesenchymal stem cells alleviate atopic dermatitis

(2018) Byong Seung Cho et al.   Stem Cell Research & Therapy

Perspective: Mutations in Recessive Congenital Ichthyoses Illuminate the Origin and Functions of the Corneocyte Lipid Envelope

(2018) Debra Crumrine et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Mesenchymal Stem Cell Therapy for Inflammatory Skin Diseases: Clinical Potential and Mode of Action

(2017) Tae-Hoon Shin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lipid Abnormalities Associated with Skin Lesions in Atopic Dermatitis

(2017) Evgeny Berdyshev et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Reduction of long-chain fatty acid ceramides in dermatitis caused by repeated exposure to house-dust mite in NC/Nga mice

(2017) Hiroyuki Kanoh et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Concise Review: MSC-Derived Exosomes for Cell-Free Therapy

(2017) Donald G. Phinney et al.   STEM CELLS

Therapeutic effects of human adipose tissue-derived stem cell (hADSC) transplantation on experimental autoimmune encephalomyelitis (EAE) mice

(2017) Jia Li et al.   Scientific Reports

Intercellular and intracellular functions of ceramides and their metabolites in skin (Review)

(2016) HWA JUN CHA et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

ER stress stimulates production of the key antimicrobial peptide, cathelicidin, by forming a previously unidentified intracellular S1P signaling complex

(2016) Kyungho Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adipose Tissue-Derived Mesenchymal Stem Cells Induce Expansion of Interleukin-10-Producing Regulatory B Cells and Ameliorate Autoimmunity in a Murine Model of Systemic Lupus Erythematosus

(2015) Min-Jung Park et al.   CELL TRANSPLANTATION

Sphingosine kinase 1 activation enhances epidermal innate immunity through sphingosine-1-phosphate stimulation of cathelicidin production

(2015) Se Kyoo Jeong et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Mass Spectrometric Confirmation of γ-Linolenic Acid Ester-Linked Ceramide 1 in the Epidermis of Borage Oil Fed Guinea Pigs

(2015) Kyong-Oh Shin et al.   LIPIDS

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Mesenchymal stem cell exosomes

(2015) Ruenn Chai Lai et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Ginsenoside compound K inhibits angiogenesis via regulation of sphingosine kinase-1 in human umbilical vein endothelial cells

(2014) Kyong-Oh Shin et al.   ARCHIVES OF PHARMACAL RESEARCH

Mechanisms of abnormal lamellar body secretion and the dysfunctional skin barrier in patients with atopic dermatitis

(2014) Peter M. Elias et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

MSC-derived exosomes: a novel tool to treat therapy-refractory graft-versus-host disease

(2014) L Kordelas et al.   LEUKEMIA

The Epithelial Cell-Derived Atopic Dermatitis Cytokine TSLP Activates Neurons to Induce Itch

(2013) Sarah R. Wilson et al.   CELL

Epidermal TSLP: a trigger factor for pathogenesis of atopic dermatitis

(2013) Arup K Indra   Expert Review of Proteomics

Barrier Abnormality Due to Ceramide Deficiency Leads to Psoriasiform Inflammation in a Mouse Model

(2013) Kimiko Nakajima et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury

(2013) Fatih Arslan et al.   Stem Cell Research

New Insights into Atopic Dermatitis: Role of Skin Barrier and Immune Dysregulation

(2013) Donald Y.M. Leung   ALLERGOLOGY INTERNATIONAL

Exosomes Mediate the Cytoprotective Action of Mesenchymal Stromal Cells on Hypoxia-Induced Pulmonary Hypertension

(2012) Changjin Lee et al.   CIRCULATION

Immune Regulatory Properties of Allogeneic Adipose-Derived Mesenchymal Stem Cells in the Treatment of Experimental Autoimmune Diabetes

(2012) E. J. Bassi et al.   DIABETES

TSLP Produced by Keratinocytes Promotes Allergen Sensitization through Skin and Thereby Triggers Atopic March in Mice

(2012) Juan Manuel Leyva-Castillo et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A Novel Role of a Lipid Species, Sphingosine-1-Phosphate, in Epithelial Innate Immunity

(2012) K. Park et al.   MOLECULAR AND CELLULAR BIOLOGY

Investigating International Time Trends in the Incidence and Prevalence of Atopic Eczema 1990–2010: A Systematic Review of Epidemiological Studies

(2012) Ivette A. G. Deckers et al.   PLoS One

TSLP enhances the function of helper type 2 cells

(2011) Masayuki Kitajima et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Atopic dermatitis: a disease of altered skin barrier and immune dysregulation

(2011) Mark Boguniewicz et al.   IMMUNOLOGICAL REVIEWS

Decrease of Ceramides with Very Long–Chain Fatty Acids and Downregulation of Elongases in a Murine Atopic Dermatitis Model

(2011) Yang-Hui Park et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Risk factors in the development of stem cell therapy

(2011) Carla A Herberts et al.   Journal of Translational Medicine

Characterization of sphingosine-1-phosphate lyase activity by electrospray ionization–liquid chromatography/tandem mass spectrometry quantitation of (2E)-hexadecenal

(2010) Evgeny V. Berdyshev et al.   ANALYTICAL BIOCHEMISTRY

Therapeutic Implications of a Barrier-Based Pathogenesis of Atopic Dermatitis

(2010) Peter M. Elias et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

The role of thymic stromal lymphopoietin (TSLP) in allergic disorders

(2010) Steven F Ziegler   CURRENT OPINION IN IMMUNOLOGY

Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury

(2010) Ruenn Chai Lai et al.   Stem Cell Research

The Potential of Adipose Stem Cells in Regenerative Medicine

(2010) Bettina Lindroos et al.   Stem Cell Reviews and Reports

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells

(2009) Manuel A. González et al.   ARTHRITIS AND RHEUMATISM

Ceramide biosynthesis in keratinocyte and its role in skin function

(2009) Yukiko Mizutani et al.   BIOCHIMIE

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis

(2009) E Gonzalez-Rey et al.   GUT

The skin: an indispensable barrier

(2008) Ehrhardt Proksch et al.   EXPERIMENTAL DERMATOLOGY

Basis for the barrier abnormality in atopic dermatitis: Outside-inside-outside pathogenic mechanisms

(2008) Peter M. Elias et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY