Ginsenoside compound K inhibits angiogenesis via regulation of sphingosine kinase-1 in human umbilical vein endothelial cells

Sphingolipid Signaling and Hematopoietic Malignancies: To the Rheostat and Beyond

(2012) Kenneth C. Loh et al.   Anti-Cancer Agents in Medicinal Chemistry

Sphingosine-1-Phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis

(2012) M. Nagahashi et al.   CANCER RESEARCH

Ginsenoside-Rg1 mediates a hypoxia-independent upregulation of hypoxia-inducible factor-1α to promote angiogenesis

(2011) Kar-Wah Leung et al.   ANGIOGENESIS

Ginsenoside Rb1 and its metabolite compound K inhibit IRAK-1 activation—The key step of inflammation

(2011) Eun-Ha Joh et al.   BIOCHEMICAL PHARMACOLOGY

Intracellular S1P Generation Is Essential for S1P-Induced Motility of Human Lung Endothelial Cells: Role of Sphingosine Kinase 1 and S1P Lyase

(2011) Evgeny V. Berdyshev et al.   PLoS One

S1P metabolism in cancer and other pathological conditions

(2010) Weng In Leong et al.   BIOCHIMIE

Compound K Inhibits Basic Fibroblast Growth Factor-Induced Angiogenesis via Regulation of p38 Mitogen Activated Protein Kinaseand AKT in Human Umbilical Vein Endothelial Cells

(2010) Arong Jeong et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Ginsenoside-Rg1 induces angiogenesis via non-genomic crosstalk of glucocorticoid receptor and fibroblast growth factor receptor-1

(2010) L. W. T. Cheung et al.   CARDIOVASCULAR RESEARCH

Ginsenoside Compound K Attenuates Metastatic Growth of Hepatocellular Carcinoma, which Is Associated with the Translocation of Nuclear Factor-κB p65 and Reduction of Matrix Metalloproteinase-2/9

(2010) Yanlin Ming et al.   PLANTA MEDICA

Disruption of ceramide synthesis by CerS2 down-regulation leads to autophagy and the unfolded protein response

(2009) Stefka D. Spassieva et al.   BIOCHEMICAL JOURNAL

Compound K, Intestinal Metabolite of Ginsenoside, Attenuates Hepatic Lipid Accumulation via AMPK Activation in Human Hepatoma Cells

(2009) Do Yeon Kim et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Activation of sphingosine kinase-1 mediates induction of endothelial cell proliferation and angiogenesis by epoxyeicosatrienoic acids

(2008) G. Yan et al.   CARDIOVASCULAR RESEARCH

Targeting SphK1 as a New Strategy against Cancer

(2008) Dai Shida et al.   CURRENT DRUG TARGETS