circRNAs Signature as Potential Diagnostic and Prognostic Biomarker for Diabetes Mellitus and Related Cardiovascular Complications

Accurate quantification of circular RNAs identifies extensive circular isoform switching events

(2020) Jinyang Zhang et al.   Nature Communications

New Perspective in Diabetic Neuropathy: From the Periphery to the Brain, a Call for Early Detection, and Precision Medicine

(2020) Heng Yang et al.   Frontiers in Endocrinology

Hsa_circRNA_0054633 is highly expressed in gestational diabetes mellitus and closely related to glycosylation index

(2019) Hangyu Wu et al.   Clinical Epigenetics

CircFunBase: a database for functional circular RNAs

(2019) Xianwen Meng et al.   Database-The Journal of Biological Databases and Curation

Targeting pericyte–endothelial cell crosstalk by circular RNA-cPWWP2A inhibition aggravates diabetes-induced microvascular dysfunction

(2019) Chang Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetics and epigenomics in diabetic kidney disease and metabolic memory

(2019) Mitsuo Kato et al.   Nature Reviews Nephrology

Circbank: a comprehensive database for circRNA with standard nomenclature

(2019) Ming Liu et al.   RNA Biology

Past, present, and future of circ RNA s

(2019) Ines Lucia Patop et al.   EMBO JOURNAL

Circular RNAs in hypertension: challenges and clinical promise

(2019) Mohamed Zaiou   HYPERTENSION RESEARCH

Microarray analyses of lncRNAs and mRNAs expression profiling associated with diabetic peripheral neuropathy in rats

(2019) Guojun Guo et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Identification of miRNAs-genes regulatory network in diabetic nephropathy based on bioinformatics analysis

(2019) Fengying Yang et al.   MEDICINE

A Novel Circular RNA Mediates Pyroptosis of Diabetic Cardiomyopathy by Functioning as a Competing Endogenous RNA

(2019) Fan Yang et al.   Molecular Therapy-Nucleic Acids

circMeta: a unified computational framework for genomic feature annotation and differential expression analysis of circular RNAs

(2019) Li Chen et al.   BIOINFORMATICS

Insights into the Role of MicroRNAs in the Onset and Development of Diabetic Neuropathy

(2019) Raffaele Simeoli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The biogenesis, biology and characterization of circular RNAs

(2019) Lasse S. Kristensen et al.   NATURE REVIEWS GENETICS

Exosomes and Their Noncoding RNA Cargo Are Emerging as New Modulators for Diabetes Mellitus

(2019) Wenguang Chang et al.   Cells

Up-regulation of microRNA-203 inhibits myocardial fibrosis and oxidative stress in mice with diabetic cardiomyopathy through the inhibition of PI3K/Akt signaling pathway via PIK3CA

(2019) Xubin Yang et al.   GENE

Circ_0080425 inhibits cell proliferation and fibrosis in diabetic nephropathy via sponging miR‐24‐3p and targeting fibroblast growth factor 11

(2019) Huifang Liu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

CircCode: A Powerful Tool for Identifying circRNA Coding Ability

(2019) Peisen Sun et al.   Frontiers in Genetics

Circular RNA ACR relieves high glucose‐aroused RSC96 cell apoptosis and autophagy via declining microRNA‐145‐3p

(2019) Ying Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Circular RNA expression profiles in placental villi from women with gestational diabetes mellitus

(2018) Linping Yan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Alterations of circular RNAs in hyperglycemic human endothelial cells

(2018) Fei-Fei Shang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The interplay between noncoding RNAs and insulin in diabetes

(2018) Yan Tian et al.   CANCER LETTERS

Prevalence of cardiovascular disease in type 2 diabetes: a systematic literature review of scientific evidence from across the world in 2007–2017

(2018) Thomas R. Einarson et al.   Cardiovascular Diabetology

Diabetic Cardiomyopathy

(2018) Guanghong Jia et al.   CIRCULATION RESEARCH

IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045

(2018) N.H. Cho et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Human circular RNA‑0054633 regulates high glucose‑induced vascular endothelial cell dysfunction through the microRNA‑218/roundabout 1 and microRNA‑218/heme oxygenase‑1 axes

(2018) Long Pan et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Computational Strategies for Exploring Circular RNAs

(2018) Yuan Gao et al.   TRENDS IN GENETICS

MicroRNA and Microvascular Complications of Diabetes

(2018) F. Barutta et al.   International Journal of Endocrinology

Circulating MicroRNAs as Biomarkers of Gestational Diabetes Mellitus: Updates and Perspectives

(2018) Elisa Guarino et al.   International Journal of Endocrinology

CircR2Disease: a manually curated database for experimentally supported circular RNAs associated with various diseases

(2018) Chunyan Fan et al.   Database-The Journal of Biological Databases and Curation

A 360° view of circular RNAs: From biogenesis to functions

(2018) Jeremy E. Wilusz   Wiley Interdisciplinary Reviews-RNA

Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables

(2018) Emma Ahlqvist et al.   Lancet Diabetes & Endocrinology

Circular RNAs as novel regulators of β-cell functions in normal and disease conditions

(2018) Lisa Stoll et al.   Molecular Metabolism

TRCirc: a resource for transcriptional regulation information of circRNAs

(2018) Zhidong Tang et al.   BRIEFINGS IN BIOINFORMATICS

Long noncoding RNAs: A new player in the prevention and treatment of diabetic cardiomyopathy?

(2018) Chao Ma et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Circular RNA circRNA_15698 aggravates the extracellular matrix of diabetic nephropathy mesangial cells via miR-185/TGF-β1

(2018) Wei Hu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Biogenesis, Functions, and Challenges of Circular RNAs

(2018) Xiang Li et al.   MOLECULAR CELL

ANRIL: A lncRNA at the CDKN2A/B Locus With Roles in Cancer and Metabolic Disease

(2018) Yahui Kong et al.   Frontiers in Endocrinology

CIRCpedia v2: An Updated Database for Comprehensive Circular RNA Annotation and Expression Comparison

(2018) Rui Dong et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

High glucose-induced circHIPK3 downregulation mediates endothelial cell injury

(2018) Ying Cao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Intrathecal circHIPK3 shRNA alleviates neuropathic pain in diabetic rats

(2018) Liang Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Circular RNAs and Their Emerging Roles in Immune Regulation

(2018) Lan Yang et al.   Frontiers in Immunology

The Diagnostic Value of Whole Blood lncRNA ENST00000550337.1 for Pre-Diabetes and Type 2 Diabetes Mellitus

(2017) Xuejie Li et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Downregulation of lncRNA ANRIL represses tumorigenicity and enhances cisplatin-induced cytotoxicity via regulating microRNA let-7a in nasopharyngeal carcinoma

(2017) Yandan Wang et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Plasma microRNA-16-5p, -17-5p and -20a-5p: Novel diagnostic biomarkers for gestational diabetes mellitus

(2017) Ya-Lei Cao et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Translation of CircRNAs

(2017) Nagarjuna Reddy Pamudurti et al.   MOLECULAR CELL

exoRBase: a database of circRNA, lncRNA and mRNA in human blood exosomes

(2017) Shengli Li et al.   NUCLEIC ACIDS RESEARCH

CSCD: a database for cancer-specific circular RNAs

(2017) Siyu Xia et al.   NUCLEIC ACIDS RESEARCH

Altered Expression Profile of Circular RNAs in the Serum of Patients with Diabetic Retinopathy Revealed by Microarray

(2017) Yonghao Gu et al.   OPHTHALMIC RESEARCH

Small but Mighty: Functional Peptides Encoded by Small ORFs in Plants

(2017) Polly Yingshan Hsu et al.   PROTEOMICS

Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1

(2017) Kotb Abdelmohsen et al.   RNA Biology

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function

(2017) Monika Piwecka et al.   SCIENCE

lncRNA MIAT functions as a competing endogenous RNA to upregulate DAPK2 by sponging miR-22-3p in diabetic cardiomyopathy

(2017) Xiang Zhou et al.   Cell Death & Disease

High glucose promotes vascular smooth muscle cell proliferation by upregulating proto-oncogene serine/threonine-protein kinase Pim-1 expression

(2017) Keke Wang et al.   Oncotarget

CircRNA_000203 enhances the expression of fibrosis-associated genes by derepressing targets of miR-26b-5p, Col1a2 and CTGF, in cardiac fibroblasts

(2017) Chun-Mei Tang et al.   Scientific Reports

Silencing Of Circular RNA-ZNF609 Ameliorates Vascular Endothelial Dysfunction

(2017) Chang Liu et al.   Theranostics

Circular RNAs in Cardiovascular Disease: An Overview

(2017) Ximin Fan et al.   Biomed Research International

Identification of the Spinal Expression Profile of Non-coding RNAs Involved in Neuropathic Pain Following Spared Nerve Injury by Sequence Analysis

(2017) Jun Zhou et al.   Frontiers in Molecular Neuroscience

circlncRNAnet: An integrated web-based resource for mapping functional networks of long or circular forms of non-coding RNAs

(2017) Shao-Min Wu et al.   GigaScience

Long Noncoding RNAs in Diabetes and Diabetic Complications

(2017) Amy Leung et al.   ANTIOXIDANTS & REDOX SIGNALING

Hsa_circ_0054633 in peripheral blood can be used as a diagnostic biomarker of pre-diabetes and type 2 diabetes mellitus

(2016) Zhenzhou Zhao et al.   ACTA DIABETOLOGICA

Comprehensive characterization of tissue-specific circular RNAs in the human and mouse genomes

(2016) Siyu Xia et al.   BRIEFINGS IN BIOINFORMATICS

Involvement of long noncoding RNA MALAT1 in the pathogenesis of diabetic cardiomyopathy

(2016) Mengyao Zhang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Targeting hepatic glucose metabolism in the treatment of type 2 diabetes

(2016) Amy K. Rines et al.   NATURE REVIEWS DRUG DISCOVERY

Endogenous microRNA sponges: evidence and controversy

(2016) Daniel W. Thomson et al.   NATURE REVIEWS GENETICS

The biogenesis and emerging roles of circular RNAs

(2016) Ling-Ling Chen   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2

(2016) William W. Du et al.   NUCLEIC ACIDS RESEARCH

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

(2016) Qiupeng Zheng et al.   Nature Communications

Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans

(2016) Lesca M. Holdt et al.   Nature Communications

Reciprocal Changes of Circulating Long Non-Coding RNAs ZFAS1 and CDR1AS Predict Acute Myocardial Infarction

(2016) Ying Zhang et al.   Scientific Reports

The Circular RNA Cdr1as Promotes Myocardial Infarction by Mediating the Regulation of miR-7a on Its Target Genes Expression

(2016) Hai-Hua Geng et al.   PLoS One

circRNADb: A comprehensive database for human circular RNAs with protein-coding annotations

(2016) Xiaoping Chen et al.   Scientific Reports

Identification and Characterization of Hypoxia-Regulated Endothelial Circular RNANovelty and Significance

(2015) Jes-Niels Boeckel et al.   CIRCULATION RESEARCH

Epigenetics and Metabolism

(2015) S. T. Keating et al.   CIRCULATION RESEARCH

The MicroRNAs in the Pathogenesis of Metabolic Memory

(2015) Xueyu Zhong et al.   ENDOCRINOLOGY

Profiling maternal plasma microRNA expression in early pregnancy to predict gestational diabetes mellitus

(2015) Yanan Zhu et al.   INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS

Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity

(2015) Xintian You et al.   NATURE NEUROSCIENCE

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CircNet: a database of circular RNAs derived from transcriptome sequencing data

(2015) Yu-Chen Liu et al.   NUCLEIC ACIDS RESEARCH

Circular RNA participates in the carcinogenesis and the malignant behavior of cancer

(2015) Zhen-Jun Zhao et al.   RNA Biology

CircInteractome: A web tool for exploring circular RNAs and their interacting proteins and microRNAs

(2015) Dawood B. Dudekula et al.   RNA Biology

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells

(2015) Huanyu Xu et al.   Scientific Reports

Circulating Long Noncoding RNA, LIPCAR, Predicts Survival in Patients With Heart Failure

(2014) Regalla Kumarswamy et al.   CIRCULATION RESEARCH

Role of epigenetic mechanisms in the development of chronic complications of diabetes

(2014) Malgorzata Wegner et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Molecular mechanisms of diabetic cardiomyopathy

(2014) Heiko Bugger et al.   DIABETOLOGIA

Epigenetic mechanisms in diabetic complications and metabolic memory

(2014) Marpadga A. Reddy et al.   DIABETOLOGIA

MicroRNA-7a regulates pancreatic β cell function

(2014) Mathieu Latreille et al.   JOURNAL OF CLINICAL INVESTIGATION

circRNA Biogenesis Competes with Pre-mRNA Splicing

(2014) Reut Ashwal-Fluss et al.   MOLECULAR CELL

Detecting and characterizing circular RNAs

(2014) William R Jeck et al.   NATURE BIOTECHNOLOGY

circBase: a database for circular RNAs

(2014) Petar Glažar et al.   RNA

A Brief History of Epigenetics

(2014) G. Felsenfeld   Cold Spring Harbor Perspectives in Biology

Role of phospholipases A2 in diabetic retinopathy: In vitro and in vivo studies

(2013) Gabriella Lupo et al.   BIOCHEMICAL PHARMACOLOGY

Circular Intronic Long Noncoding RNAs

(2013) Yang Zhang et al.   MOLECULAR CELL

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

Circulating microRNAs as novel biomarkers for diabetes mellitus

(2013) Claudiane Guay et al.   Nature Reviews Endocrinology

starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data

(2013) Jun-Hao Li et al.   NUCLEIC ACIDS RESEARCH

Circ2Traits: a comprehensive database for circular RNA potentially associated with disease and traits

(2013) Suman Ghosal et al.   Frontiers in Genetics

Global Prevalence and Major Risk Factors of Diabetic Retinopathy

(2012) J. W. Y. Yau et al.   DIABETES CARE

Dysregulation of Dicer1 in Beta Cells Impairs Islet Architecture and Glucose Metabolism

(2012) Amitai D. Mandelbaum et al.   Experimental Diabetes Research

Pre-Diabetes, Metabolic Syndrome, and Cardiovascular Risk

(2012) Scott M. Grundy   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types

(2012) Julia Salzman et al.   PLoS One

Epigenetics: A Molecular Link Between Environmental Factors and Type 2 Diabetes

(2009) Charlotte Ling et al.   DIABETES

Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: Where are the insulin resistance genes?

(2008) J. C. Florez   DIABETOLOGIA