Revisiting Inflammatory Bowel Disease: Pathology, Treatments, Challenges and Emerging Therapeutics Including Drug Leads from Natural Products

Surgery in the age of biologics

(2019) Daniel J Wong et al.   Gastroenterology Report

Infliximab in inflammatory bowel disease

(2019) Konstantinos Papamichael et al.   Therapeutic Advances in Chronic Disease

Long-term evolution of direct healthcare costs for inflammatory bowel diseases: a population-based study (2006–2015)

(2019) Jung-Wook Kim et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Hookworm-Derived Metabolites Suppress Pathology in a Mouse Model of Colitis and Inhibit Secretion of Key Inflammatory Cytokines in Primary Human Leukocytes

(2019) Phurpa Wangchuk et al.   INFECTION AND IMMUNITY

Induction and maintenance treatment of inflammatory bowel disease: A comprehensive review

(2019) Dong Yeon Jeong et al.   AUTOIMMUNITY REVIEWS

Cytokine Networks in the Pathophysiology of Inflammatory Bowel Disease

(2019) Matthias Friedrich et al.   IMMUNITY

The Cost of Inflammatory Bowel Disease: An Initiative From the Crohn’s & Colitis Foundation

(2019) K T Park et al.   INFLAMMATORY BOWEL DISEASES

Characterization of Tapeworm Metabolites and Their Reported Biological Activities

(2019) Phurpa Wangchuk et al.   MOLECULES

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

(2019) Jason Lloyd-Price et al.   NATURE

Plant-Derived Alkaloids: The Promising Disease-Modifying Agents for Inflammatory Bowel Disease

(2019) Jiao Peng et al.   Frontiers in Pharmacology

Golimumab for Rheumatoid Arthritis

(2019) Eleftherios Pelechas et al.   Journal of Clinical Medicine

Metabolomic profiling of the excretory–secretory products of hookworm and whipworm

(2019) Phurpa Wangchuk et al.   Metabolomics

AICD: an integrated anti-inflammatory compounds database for drug discovery

(2019) Kun Wang et al.   Scientific Reports

The Use of Biologics and Biosimilar in Asian patients with IBD: Are we ready?

(2019) Joyce WY Mak et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

A Review of Anti-Inflammatory Compounds from Marine Fungi, 2000–2018

(2019) Jianzhou Xu et al.   Marine Drugs

Berberine improved experimental chronic colitis by regulating interferon-γ- and IL-17A-producing lamina propria CD4+ T cells through AMPK activation

(2019) Masahiro Takahara et al.   Scientific Reports

The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2019) Sudabeh Alatab et al.   Lancet Gastroenterology & Hepatology

Inflammatory bowel disease therapy

(2018) Jesus K. Yamamoto-Furusho   CURRENT OPINION IN GASTROENTEROLOGY

Predictors of Impaired Mental Health and Support Seeking in Adults With Inflammatory Bowel Disease

(2018) Simon Knowles et al.   Gastroenterology Nursing

Infliximab for Crohn’s Disease: More Than 13 Years of Real-world Experience

(2018) Gary R Lichtenstein et al.   INFLAMMATORY BOWEL DISEASES

Evolving Role of IBD Surgery

(2018) W A Bemelman et al.   Journal of Crohns & Colitis

A medicinal plant compound, capnoidine, prevents the onset of inflammation in a mouse model of colitis

(2018) Catherine Shepherd et al.   JOURNAL OF ETHNOPHARMACOLOGY

Review of anti-inflammatory, immune-modulatory and wound healing properties of molluscs

(2018) Tarek B. Ahmad et al.   JOURNAL OF ETHNOPHARMACOLOGY

Berberrubine attenuates mucosal lesions and inflammation in dextran sodium sulfate-induced colitis in mice

(2018) Xiu-Ting Yu et al.   PLoS One

The Untapped Pharmacopeic Potential of Helminths

(2018) Janina Kahl et al.   TRENDS IN PARASITOLOGY

Vedolizumab for inflammatory bowel disease: From randomized controlled trials to real-life evidence

(2018) Maria Lia Scribano   WORLD JOURNAL OF GASTROENTEROLOGY

New anti-inflammatory guaianes from the Atlantic hydrotherm-derived fungus Graphostroma sp. MCCC 3A00421

(2018) Siwen Niu et al.   Scientific Reports

Effectiveness and safety of adalimumab to treat outpatient ulcerative colitis

(2018) Antonio Tursi et al.   MEDICINE

From bench to bedside: Fecal calprotectin in inflammatory bowel diseases clinical setting

(2018) Maria Gloria Mumolo et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Analysis of the Gut Microbiome of Rural and Urban Healthy Indians Living in Sea Level and High Altitude Areas

(2018) Bhabatosh Das et al.   Scientific Reports

Emerging Therapies for Inflammatory Bowel Disease

(2018) Roni Weisshof et al.   ADVANCES IN THERAPY

Antimicrobial treatment with the fixed-dose antibiotic combination RHB-104 for Mycobacterium avium subspecies paratuberculosis in Crohn’s disease: pharmacological and clinical implications

(2018) Edoardo Savarino et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Tofacitinib for the treatment of ulcerative colitis

(2018) Agnès Fernández-Clotet et al.   Expert Review of Clinical Immunology

Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules

(2018) Rick M. Maizels et al.   IMMUNITY

Ustekinumab Is Effective for the Treatment of Crohn’s Disease of the Pouch in a Multicenter Cohort

(2018) Kimberly N Weaver et al.   INFLAMMATORY BOWEL DISEASES

The Crohn’s & Colitis Australia Inflammatory Bowel Disease Audit: Measuring the quality of care in Australia

(2018) Wayne Massuger et al.   INTERNAL MEDICINE JOURNAL

Intestinal Anti-Inflammatory Activity of the Aqueous Extract from Ipomoea asarifolia in DNBS-Induced Colitis in Rats

(2018) Valéria da Silva et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Emerging trends of inflammatory bowel disease in South Korea: A nationwide population‐based study

(2018) Min Seob Kwak et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Preussins with Inhibition of IL-6 Expression from Aspergillus flocculosus 16D-1, a Fungus Isolated from the Marine Sponge Phakellia fusca

(2018) Bin-Bin Gu et al.   JOURNAL OF NATURAL PRODUCTS

Analgesic and Anti-Inflammatory Activities of Resveratrol through Classic Models in Mice and Rats

(2017) Guangxi Wang et al.   Evidence-based Complementary and Alternative Medicine

Golimumab for the treatment of ulcerative colitis

(2017) Mathurin Flamant et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Filgotinib in Crohn’s Disease: JAK Is Back

(2017) Silvio Danese et al.   GASTROENTEROLOGY

Nature is the best source of anti-inflammatory drugs: indexing natural products for their anti-inflammatory bioactivity

(2017) Miran Aswad et al.   INFLAMMATION RESEARCH

An engineered cyclic peptide alleviates symptoms of inflammation in a murine model of inflammatory bowel disease

(2017) Claudia Cobos Caceres et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ECCO-ESCP Consensus on Surgery for Crohn’s Disease

(2017) Willem A. Bemelman et al.   Journal of Crohns & Colitis

Antibiotic Use and New-Onset Inflammatory Bowel Disease in Olmsted County, Minnesota: A Population-Based Case-Control Study

(2017) Satimai Aniwan et al.   Journal of Crohns & Colitis

Ulcerative colitis

(2017) Ryan Ungaro et al.   LANCET

Asperflavin, an Anti-Inflammatory Compound Produced by a Marine-Derived Fungus, Eurotium amstelodami

(2017) Xiudong Yang et al.   MOLECULES

Current and emerging therapeutic targets for IBD

(2017) Markus F. Neurath   Nature Reviews Gastroenterology & Hepatology

Tofacitinib as Induction and Maintenance Therapy for Ulcerative Colitis

(2017) William J. Sandborn et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sesquiterpenes from a deep-sea-derived fungus Graphostroma sp. MCCC 3A00421

(2017) Siwen Niu et al.   TETRAHEDRON

Therapeutic potential of flavonoids in inflammatory bowel disease: A comprehensive review

(2017) Ali Salaritabar et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Anticancer and Anti-Inflammatory Properties of Ganoderma lucidum Extract Effects on Melanoma and Triple-Negative Breast Cancer Treatment

(2017) Antonio Barbieri et al.   Nutrients

Systematic review with meta-analysis: recurrence of Crohn's disease after total colectomy with permanent ileostomy

(2016) M. Fumery et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

The anti-inflammatory effect of Andrographis paniculata (Burm. f.) Nees on pelvic inflammatory disease in rats through down-regulation of the NF-κB pathway

(2016) Wei Zou et al.   BMC Complementary and Alternative Medicine

American Ginseng Attenuates Colitis-Associated Colon Carcinogenesis in Mice: Impact on Gut Microbiota and Metabolomics

(2016) C.-Z. Wang et al.   Cancer Prevention Research

Symptoms of Depression and Anxiety Are Independently Associated With Clinical Recurrence of Inflammatory Bowel Disease

(2016) Antonina Mikocka-Walus et al.   Clinical Gastroenterology and Hepatology

Budesonide for the treatment of ulcerative colitis

(2016) Maisa I. Abdalla et al.   EXPERT OPINION ON PHARMACOTHERAPY

East Meets West: The Increasing Incidence of Inflammatory Bowel Disease in Asia as a Paradigm for Environmental Effects on the Pathogenesis of Immune-Mediated Disease

(2016) Yunsheng Yang et al.   GASTROENTEROLOGY

Next generation of small molecules in inflammatory bowel disease

(2016) Pablo Olivera et al.   GUT

The safety of vedolizumab for ulcerative colitis and Crohn's disease

(2016) Jean-Frédéric Colombel et al.   GUT

Faecal and serum metabolomics in paediatric inflammatory bowel disease

(2016) Kaija-Leena Kolho et al.   Journal of Crohns & Colitis

A Randomised, Double-blind, Placebo-controlled Trial ofTrichuris suisova in Active Crohn’s disease

(2016) Jürgen Schölmerich et al.   Journal of Crohns & Colitis

Protective Effect ofAmphipterygium adstringensExtract on Dextran Sulphate Sodium-Induced Ulcerative Colitis in Mice

(2016) Mario Rodriguez-Canales et al.   MEDIATORS OF INFLAMMATION

Anti-Inflammatory Activity of Natural Products

(2016) Abdullatif Azab et al.   MOLECULES

Ustekinumab as Induction and Maintenance Therapy for Crohn’s Disease

(2016) Brian G. Feagan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sleep disturbances in Japanese patients with inflammatory bowel disease and their impact on disease flare

(2016) Risa Uemura et al.   SpringerPlus

Mesalazine in Inflammatory Bowel Disease: A Trendy Topic Once Again?

(2016) Marietta Iacucci et al.   CANADIAN JOURNAL OF GASTROENTEROLOGY

Inflammatory Bowel Disease in Immigrants to Canada And Their Children: A Population-Based Cohort Study

(2015) Eric I Benchimol et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Tripterygium wilfordii Hook F as Maintenance Treatment for Crohn's Disease

(2015) Jing Sun et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Antiinflammatory and Analgesic Activities of Ethanol Extract and Isolated Compounds from Millettia pulchra

(2015) Xiaowei Huo et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

T cell subsets and their signature cytokines in autoimmune and inflammatory diseases

(2015) Itay Raphael et al.   CYTOKINE

Blood-based Biomarkers Used to Predict Disease Activity in Crohnʼs Disease and Ulcerative Colitis

(2015) Robert Burakoff et al.   INFLAMMATORY BOWEL DISEASES

Treatment with Egg Antigens of Schistosoma mansoni Ameliorates Experimental Colitis in Mice Through a Colonic T-cell–dependent Mechanism

(2015) Marthe Heylen et al.   INFLAMMATORY BOWEL DISEASES

Biologic agents for IBD: practical insights

(2015) Silvio Danese et al.   Nature Reviews Gastroenterology & Hepatology

The global burden of IBD: from 2015 to 2025

(2015) Gilaad G. Kaplan   Nature Reviews Gastroenterology & Hepatology

Epidemiology and risk factors for IBD

(2015) Ashwin N. Ananthakrishnan   Nature Reviews Gastroenterology & Hepatology

Current scenario in inflammatory bowel disease: Drug development prospects

(2015) Shammy Chandel et al.   Pharmacological Reports

Diterpenoid alkaloids of Aconitum laciniatum and mitigation of inflammation by 14-O-acetylneoline in a murine model of ulcerative colitis

(2015) Phurpa Wangchuk et al.   Scientific Reports

Sa1968 Distinct Microbiotas Are Present in Urban and Rural Native South Africans, and in African Americans

(2015) Erwin G. Zoetendal et al.   GASTROENTEROLOGY

Fecal Calprotectin Concentrations in Healthy Children Aged 1-18 Months

(2015) Feng Li et al.   PLoS One

Sleep Duration Affects Risk for Ulcerative Colitis: A Prospective Cohort Study

(2014) Ashwin N. Ananthakrishnan et al.   Clinical Gastroenterology and Hepatology

Place of upbringing in early childhood as related to inflammatory bowel diseases in adulthood: a population-based cohort study in Northern Europe

(2014) Signe Timm et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Environmental risk factors in inflammatory bowel disease: a population-based case-control study in Asia-Pacific

(2014) Siew C Ng et al.   GUT

IL-9 and its receptor are predominantly involved in the pathogenesis of UC

(2014) Nancy Nalleweg et al.   GUT

The Commensal Bacterium Faecalibacterium prausnitzii Is Protective in DNBS-induced Chronic Moderate and Severe Colitis Models

(2014) Rebeca Martín et al.   INFLAMMATORY BOWEL DISEASES

Future directions in inflammatory bowel disease management

(2014) Geert R. D'Haens et al.   Journal of Crohns & Colitis

Intestinal anti-inflammatory activity of the Serpylli herba extract in experimental models of rodent colitis

(2014) Francesca Algieri et al.   Journal of Crohns & Colitis

Mortality and causes of death in patients with inflammatory bowel disease: A nationwide register study in Finland

(2014) Airi Jussila et al.   Journal of Crohns & Colitis

European evidence based consensus on surgery for ulcerative colitis

(2014) Tom Øresland et al.   Journal of Crohns & Colitis

Systematic Review of Complementary and Alternative Medicine Treatments in Inflammatory Bowel Diseases

(2014) J. Langhorst et al.   Journal of Crohns & Colitis

Phenotypic and Functional Characterization of Ultraviolet Radiation-Induced Regulatory T Cells

(2014) A. Maeda et al.   JOURNAL OF IMMUNOLOGY

Mushrooms: A Potential Natural Source of Anti-Inflammatory Compounds for Medical Applications

(2014) Elsayed A. Elsayed et al.   MEDIATORS OF INFLAMMATION

Potent Anti-Inflammatory Activity of Pyrenocine A Isolated from the Marine-Derived FungusPenicillium paxilliMa(G)K

(2014) Thaís Regina Toledo et al.   MEDIATORS OF INFLAMMATION

Of worms, mice and man: An overview of experimental and clinical helminth-based therapy for inflammatory bowel disease

(2014) Marthe Heylen et al.   PHARMACOLOGY & THERAPEUTICS

IL-6 Stimulates Intestinal Epithelial Proliferation and Repair after Injury

(2014) Kristine A. Kuhn et al.   PLoS One

Inflammatory bowel disease: Pathogenesis

(2014) Yi-Zhen Zhang   WORLD JOURNAL OF GASTROENTEROLOGY

Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse posttraumatic osteoarthritis model

(2014) Daniel J Leong et al.   ARTHRITIS RESEARCH & THERAPY

Animal models of inflammatory bowel disease: a review

(2014) Nidhi Goyal et al.   INFLAMMOPHARMACOLOGY

A Total Laparoscopic Approach Reduces the Infertility Rate After Ileal Pouch-Anal Anastomosis

(2013) Laura Beyer-Berjot et al.   ANNALS OF SURGERY

Sleep Disturbance and Risk of Active Disease in Patients With Crohn's Disease and Ulcerative Colitis

(2013) Ashwin N. Ananthakrishnan et al.   Clinical Gastroenterology and Hepatology

Incidence and Phenotype of Inflammatory Bowel Disease Based on Results From the Asia-Pacific Crohn's and Colitis Epidemiology Study

(2013) Siew C. Ng et al.   GASTROENTEROLOGY

Risk of Surgery for Inflammatory Bowel Diseases Has Decreased Over Time: A Systematic Review and Meta-analysis of Population-Based Studies

(2013) Alexandra D. Frolkis et al.   GASTROENTEROLOGY

A Prospective Study of Long-term Intake of Dietary Fiber and Risk of Crohn's Disease and Ulcerative Colitis

(2013) Ashwin N. Ananthakrishnan et al.   GASTROENTEROLOGY

Non-redundant properties of IL-1α and IL-1β during acute colon inflammation in mice

(2013) Marina Bersudsky et al.   GUT

Ingestion of Low Dose Pyroglutamyl Leucine Improves Dextran Sulfate Sodium-Induced Colitis and Intestinal Microbiota in Mice

(2013) Sayori Wada et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A tale of two diseases: The history of inflammatory bowel disease

(2013) Daniel J. Mulder et al.   Journal of Crohns & Colitis

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

IBD across the age spectrum—is it the same disease?

(2013) Joannie Ruel et al.   Nature Reviews Gastroenterology & Hepatology

Restorative Procedures in Colonic Crohn Disease

(2013) Sean Martin et al.   Clinics in Colon and Rectal Surgery

Association of Repeated Exposure to Antibiotics With the Development of Pediatric Crohn's Disease--A Nationwide, Register-based Finnish Case-Control Study

(2012) L. Virta et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Andrographis paniculata Extract (HMPL-004) for Active Ulcerative Colitis

(2012) William J Sandborn et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The PepT1-transportable soy tripeptide VPY reduces intestinal inflammation

(2012) Jennifer Kovacs-Nolan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Risk of Colorectal Cancer in Patients With Ulcerative Colitis: A Meta-analysis of Population-Based Cohort Studies

(2012) Tine Jess et al.   Clinical Gastroenterology and Hepatology

A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis

(2012) Paul J Rutgeerts et al.   GUT

Geographical variation and incidence of inflammatory bowel disease among US women

(2012) Hamed Khalili et al.   GUT

Fecal calprotectin is a surrogate marker for endoscopic lesions in inflammatory bowel disease

(2012) Geert DʼHaens et al.   INFLAMMATORY BOWEL DISEASES

Second European evidence-based consensus on the diagnosis and management of ulcerative colitis Part 1: Definitions and diagnosis

(2012) Axel Dignass et al.   Journal of Crohns & Colitis

Ulcerative colitis

(2012) Ingrid Ordás et al.   LANCET

Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10 −/− mice

(2012) Suzanne Devkota et al.   NATURE

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Antibiotic Exposure and IBD Development Among Children: A Population-Based Cohort Study

(2012) M. P. Kronman et al.   PEDIATRICS

Bioassay-guided isolation of an alkaloid with antiangiogenic and antitumor activities from the extract of Fissistigma cavaleriei root

(2012) Zaichang Yang et al.   PHYTOMEDICINE

Novel, Objective, Multivariate Biomarkers Composed of Plasma Amino Acid Profiles for the Diagnosis and Assessment of Inflammatory Bowel Disease

(2012) Tadakazu Hisamatsu et al.   PLoS One

Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

(2012) Xochitl C Morgan et al.   GENOME BIOLOGY

Aspirin in the aetiology of Crohn’s disease and ulcerative colitis: a European prospective cohort study

(2011) S. S. M. Chan et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Association Between the Use of Antibiotics and New Diagnoses of Crohn's Disease and Ulcerative Colitis

(2011) Souradet Y Shaw et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The Tripeptide KdPT Protects from Intestinal Inflammation and Maintains Intestinal Barrier Function

(2011) Dominik Bettenworth et al.   AMERICAN JOURNAL OF PATHOLOGY

Proinflammatory Cytokines in the Pathogenesis of Inflammatory Bowel Diseases

(2011) Warren Strober et al.   GASTROENTEROLOGY

The mucosal addressin cell adhesion molecule antibody PF-00547,659 in ulcerative colitis: a randomised study

(2011) S. Vermeire et al.   GUT

GCMS-based metabolomic study in mice with colitis induced by dextran sulfate sodium

(2011) Yuuki Shiomi et al.   INFLAMMATORY BOWEL DISEASES

Role of the microbiota in inflammatory bowel diseases

(2011) Nabeetha A. Nagalingam et al.   INFLAMMATORY BOWEL DISEASES

Genetics and pathogenesis of inflammatory bowel disease

(2011) Bernard Khor et al.   NATURE

Clinical immunology of the sphingosine 1-phosphate receptor modulator fingolimod (FTY720) in multiple sclerosis

(2011) M. Mehling et al.   NEUROLOGY

Inhibitory effects of kaurenoic acid from Aralia continentalis on LPS-induced inflammatory response in RAW264.7 macrophages

(2011) Ran Joo Choi et al.   PHYTOMEDICINE

Preventive and Therapeutic Euphol Treatment Attenuates Experimental Colitis in Mice

(2011) Rafael C. Dutra et al.   PLoS One

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Certolizumab pegol for the treatment of Crohn’s disease

(2011) Stefan Schreiber   Therapeutic Advances in Gastroenterology

Clinical trial: five or ten cycles of granulocyte-monocyte apheresis show equivalent efficacy and safety in ulcerative colitis

(2010) A. U. DIGNASS et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Association Between the Use of Antibiotics in the First Year of Life and Pediatric Inflammatory Bowel Disease

(2010) Souradet Y Shaw et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The mode of actions of the Adacolumn therapeutic leucocytapheresis in patients with inflammatory bowel disease: a concise review

(2010) H. Hanai et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Certolizumab Pegol in Patients With Moderate to Severe Crohn's Disease and Secondary Failure to Infliximab

(2010) William J. Sandborn et al.   Clinical Gastroenterology and Hepatology

Sleep disturbances and inflammatory bowel disease: a potential trigger for disease flare?

(2010) Garth R Swanson et al.   Expert Review of Clinical Immunology

T1259 Serum Metabolite Profiles Differentiate Crohn's Disease From Ulcerative Colitis and From Healthy Controls

(2010) Colette Johnston et al.   GASTROENTEROLOGY

Antibiotic use and inflammatory bowel diseases in childhood

(2010) A. Hviid et al.   GUT

Peripheral blood MicroRNAs distinguish active ulcerative colitis and Crohnʼs disease

(2010) Feng Wu et al.   INFLAMMATORY BOWEL DISEASES

Report of the ECCO pathogenesis workshop on anti-TNF therapy failures in inflammatory bowel diseases: Definitions, frequency and pharmacological aspects

(2010) Matthieu Allez et al.   Journal of Crohns & Colitis

The Coevolution of Virulence: Tolerance in Perspective

(2010) Tom J. Little et al.   PLoS Pathogens

Biological Therapies for Inflammatory Bowel Diseases

(2009) Paul Rutgeerts et al.   GASTROENTEROLOGY

Low counts of Faecalibacterium prausnitzii in colitis microbiota

(2009) H. Sokol et al.   INFLAMMATORY BOWEL DISEASES

Zedoarondiol isolated from the rhizoma of Curcuma heyneana is involved in the inhibition of iNOS, COX-2 and pro-inflammatory cytokines via the downregulation of NF-κB pathway in LPS-stimulated murine macrophages

(2009) Woong Cho et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Infection withHymenolepis diminutaIs More Effective than Daily Corticosteroids in Blocking Chemically Induced Colitis in Mice

(2009) Alexandra Melon et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Prevalence of ulcerative colitis and Crohn’s disease in Japan

(2009) Keiko Asakura et al.   JOURNAL OF GASTROENTEROLOGY

Metabonomics in Ulcerative Colitis: Diagnostics, Biomarker Identification, And Insight into the Pathophysiology

(2009) Jacob T. Bjerrum et al.   JOURNAL OF PROTEOME RESEARCH

Metabolomics Reveals Metabolic Biomarkers of Crohn's Disease

(2009) Janet Jansson et al.   PLoS One

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

(2009) P. J. Turnbaugh et al.   Science Translational Medicine

Inhibitors of Tubulin Assembly Identified through Screening a Compound Library

(2008) Rachel E. Morgan et al.   Chemical Biology & Drug Design

Natural products in drug discovery

(2008) A HARVEY   DRUG DISCOVERY TODAY

Direct Health Care Costs of Crohn's Disease and Ulcerative Colitis in US Children and Adults

(2008) Michael D. Kappelman et al.   GASTROENTEROLOGY

What is the importance of appendectomy in the natural history of IBD?

(2008) G. L. Radford-Smith   INFLAMMATORY BOWEL DISEASES

Epithelial apoptosis is a prominent feature of the epithelial barrier disturbance in intestinal inflammation: effect of pro-inflammatory interleukin-13 on epithelial cell function

(2008) F Heller et al.   Mucosal Immunology

Scaffold diversity of natural products: inspiration for combinatorial library design

(2008) Kristina Grabowski et al.   NATURAL PRODUCT REPORTS

Polysaccharide utilization by gut bacteria: potential for new insights from genomic analysis

(2008) Harry J. Flint et al.   NATURE REVIEWS MICROBIOLOGY

Parasitic helminths: a pharmacopeia of anti-inflammatory molecules

(2008) M. J. G. JOHNSTON et al.   PARASITOLOGY

PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation

(2007) Guillaume Dalmasso et al.   GASTROENTEROLOGY