IL-9 and its receptor are predominantly involved in the pathogenesis of UC

Human TH9 Cells Are Skin-Tropic and Have Autocrine and Paracrine Proinflammatory Capacity

(2014) C. Schlapbach et al.   Science Translational Medicine

Adalimumab prevents barrier dysfunction and antagonizes distinct effects of TNF-α on tight junction proteins and signaling pathways in intestinal epithelial cells

(2013) Andreas Fischer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Th9 cells: differentiation and disease

(2013) Mark H. Kaplan   IMMUNOLOGICAL REVIEWS

New targets for mucosal healing and therapy in inflammatory bowel diseases

(2013) M F Neurath   Mucosal Immunology

How Cytokine Networks Fuel Inflammation: Toward a cytokine-based disease taxonomy

(2013) Georg Schett et al.   NATURE MEDICINE

Neutrophil Function: From Mechanisms to Disease

(2012) Borko Amulic et al.   Annual Review of Immunology

Animal Models of Inflammatory Bowel Diseases: Illuminating the Pathogenesis of Colitis, Ileitis and Cancer

(2012) Markus F. Neurath   DIGESTIVE DISEASES

Whatʼs the next best cytokine target in IBD?

(2012) Thomas T. MacDonald et al.   INFLAMMATORY BOWEL DISEASES

IL-9-producing invariant NKT cells protect against DSS-induced colitis in an IL-4-dependent manner

(2012) H S Kim et al.   Mucosal Immunology

The many lives of IL-9: a question of survival?

(2012) Christoph Wilhelm et al.   NATURE IMMUNOLOGY

Calprotectin, Calgranulin C, and Other Members of the S100 Protein Family in Inflammatory Bowel Disease

(2011) Anastassios C. Manolakis et al.   DIGESTIVE DISEASES AND SCIENCES

New therapies for inflammatory bowel disease: from the bench to the bedside

(2011) Silvio Danese   GUT

IRF4 regulates IL-17A promoter activity and controls RORγt-dependent Th17 colitis in vivo

(2011) Jonas Mudter et al.   INFLAMMATORY BOWEL DISEASES

Functional relevance of T helper 17 (Th17) cells and the IL-17 cytokine family in inflammatory bowel disease

(2011) Gheorghe Hundorfean et al.   INFLAMMATORY BOWEL DISEASES

STAT6-Dependent Regulation of Th9 Development

(2011) R. Goswami et al.   JOURNAL OF IMMUNOLOGY

An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation

(2011) Christoph Wilhelm et al.   NATURE IMMUNOLOGY

Ulcerative Colitis

(2011) Silvio Danese et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inflammatory Bowel Disease

(2010) Arthur Kaser et al.   Annual Review of Immunology

Interferon-Regulatory Factor 4 Is Essential for the Developmental Program of T Helper 9 Cells

(2010) Valérie Staudt et al.   IMMUNITY

Regulation of human Th9 differentiation by type I interferons and IL-21

(2010) Michael T Wong et al.   IMMUNOLOGY AND CELL BIOLOGY

The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation

(2010) Hua-Chen Chang et al.   NATURE IMMUNOLOGY

Human CD4+ Memory T Cells Can Become CD4+IL-9+ T Cells

(2010) Prabhakar Putheti et al.   PLoS One

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease

(2008) T Kobayashi et al.   GUT

Accumulation, activation, and survival of neutrophils in ulcerative colitis: regulation by locally produced factors in the colon and impact of steroid treatment

(2008) Maria Lampinen et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset

(2008) Marc Veldhoen et al.   NATURE IMMUNOLOGY

IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

(2008) Valérie Dardalhon et al.   NATURE IMMUNOLOGY