Force production of human cytoplasmic dynein is limited by its processivity

Force-Dependent Unbinding Rate of Molecular Motors from Stationary Optical Trap Data

(2019) Florian Berger et al.   NANO LETTERS

Dynein activators and adaptors at a glance

(2019) Mara A. Olenick et al.   JOURNAL OF CELL SCIENCE

Molecular mechanism of cytoplasmic dynein tension sensing

(2019) Lu Rao et al.   Nature Communications

Cargo adaptors regulate stepping and force generation of mammalian dynein–dynactin

(2019) Mohamed M. Elshenawy et al.   Nature Chemical Biology

Modulation of Kinesin’s Load-Bearing Capacity by Force Geometry and the Microtubule Track

(2019) Serapion Pyrpassopoulos et al.   BIOPHYSICAL JOURNAL

Hook Adaptors Induce Unidirectional Processive Motility by Enhancing the Dynein-Dynactin Interaction

(2016) Mara A. Olenick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The mammalian dynein–dynactin complex is a strong opponent to kinesin in a tug-of-war competition

(2016) Vladislav Belyy et al.   NATURE CELL BIOLOGY

How Dynein Moves Along Microtubules

(2016) Gira Bhabha et al.   TRENDS IN BIOCHEMICAL SCIENCES

Cytoplasmic dynein regulates its attachment to microtubules via nucleotide state-switched mechanosensing at multiple AAA domains

(2015) Matthew P. Nicholas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of cytoplasmic dynein force production and processivity by its C-terminal domain

(2015) Matthew P. Nicholas et al.   Nature Communications

Single-Molecule Fluorescence and in Vivo Optical Traps: How Multiple Dyneins and Kinesins Interact

(2014) Benjamin H. Blehm et al.   CHEMICAL REVIEWS

In vitroreconstitution of a highly processive recombinant human dynein complex

(2014) Max A Schlager et al.   EMBO JOURNAL

Autoinhibition and cooperative activation mechanisms of cytoplasmic dynein

(2014) Takayuki Torisawa et al.   NATURE CELL BIOLOGY

Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes

(2014) R. J. McKenney et al.   SCIENCE

Cytoplasmic dynein transports cargos via load-sharing between the heads

(2014) Vladislav Belyy et al.   Nature Communications

Modular Aspects of Kinesin Force Generation Machinery

(2013) William R. Hesse et al.   BIOPHYSICAL JOURNAL

Dynein Recruitment to Nuclear Pores Activates Apical Nuclear Migration and Mitotic Entry in Brain Progenitor Cells

(2013) Daniel Jun-Kit Hu et al.   CELL

Molecular Adaptations Allow Dynein to Generate Large Collective Forces inside Cells

(2013) Arpan K. Rai et al.   CELL

Force generation and step-size fluctuations in a dynein motor

(2013) Tripti Bameta et al.   JOURNAL OF STATISTICAL MECHANICS-THEORY AND EXPERIMENT

TRAK/Milton Motor-Adaptor Proteins Steer Mitochondrial Trafficking to Axons and Dendrites

(2013) Myrrhe van Spronsen et al.   NEURON

Enzymatic Oxygen Scavenging for Photostability without pH Drop in Single-Molecule Experiments

(2012) Marko Swoboda et al.   ACS Nano

Force-Dependent Detachment of Kinesin-2 Biases Track Switching at Cytoskeletal Filament Intersections

(2012) Harry W. Schroeder et al.   BIOPHYSICAL JOURNAL

Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein

(2012) Ari J. Firestone et al.   NATURE

Measuring collective transport by defined numbers of processive and nonprocessive kinesin motors

(2012) K. Furuta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstitution of the human cytoplasmic dynein complex

(2012) M. Trokter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recombinant human cytoplasmic dynein heavy chain 1 and 2: Observation of dynein-2 motor activity in vitro

(2011) Muneyoshi Ichikawa et al.   FEBS LETTERS

Mechanical stochastic tug-of-war models cannot explain bidirectional lipid-droplet transport

(2011) A. Kunwar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Directional Switching of the Kinesin Cin8 Through Motor Coupling

(2011) J. Roostalu et al.   SCIENCE

Nucleotide-dependent behavior of single molecules of cytoplasmic dynein on microtubules in vitro

(2010) Michi Miura et al.   FEBS LETTERS

A cytoplasmic dynein tail mutation impairs motor processivity

(2010) Kassandra M. Ori-McKenney et al.   NATURE CELL BIOLOGY

Dynein at the kinetochore: Timing, Interactions and Functions

(2010) Jason R. Bader et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Coordinating mitosis with cell polarity: Molecular motors at the cell cortex

(2010) Jeffrey K. Moore et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Cytoplasmic dynein is not a conventional processive motor

(2009) Wilhelm J. Walter et al.   JOURNAL OF STRUCTURAL BIOLOGY

Regulators of the cytoplasmic dynein motor

(2009) Julia R. Kardon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cell Cycle-Dependent Microtubule-Based Dynamic Transport of Cytoplasmic Dynein in Mammalian Cells

(2009) Takuya Kobayashi et al.   PLoS One

Regulation of the processivity and intracellular localization of Saccharomyces cerevisiae dynein by dynactin

(2009) J. R. Kardon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging roles for myosin II and cytoplasmic dynein in migrating neurons and growth cones

(2009) Richard B. Vallee et al.   TRENDS IN CELL BIOLOGY

Regulatory ATPase Sites of Cytoplasmic Dynein Affect Processivity and Force Generation

(2008) Carol Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Engineering a Novel Multifunctional Green Fluorescent Protein Tag for a Wide Variety of Protein Research

(2008) Takuya Kobayashi et al.   PLoS One

The mitotic kinesin CENP-E is a processive transport motor

(2008) H. Yardimci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Theory, analysis, and interpretation of single-molecule force spectroscopy experiments

(2008) O. K. Dudko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA