Cytoplasmic dynein regulates its attachment to microtubules via nucleotide state-switched mechanosensing at multiple AAA domains

Allosteric Communication in the Dynein Motor Domain

(2014) Gira Bhabha et al.   CELL

The AAA3 domain of cytoplasmic dynein acts as a switch to facilitate microtubule release

(2014) Mark A DeWitt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Tension on the linker gates the ATP-dependent release of dynein from microtubules

(2014) Frank B. Cleary et al.   Nature Communications

Reconstitution of dynein transport to the microtubule plus end by kinesin

(2014) Anthony J Roberts et al.   eLife

Molecular Adaptations Allow Dynein to Generate Large Collective Forces inside Cells

(2013) Arpan K. Rai et al.   CELL

Crystal clear insights into how the dynein motor moves

(2013) A. P. Carter   JOURNAL OF CELL SCIENCE

Enzymatic Oxygen Scavenging for Photostability without pH Drop in Single-Molecule Experiments

(2012) Marko Swoboda et al.   ACS Nano

Measuring Molecular Motor Forces In Vivo: Implications for Tug-of-War Models of Bidirectional Transport

(2012) Christina Leidel et al.   BIOPHYSICAL JOURNAL

Lis1 Acts as a “Clutch” between the ATPase and Microtubule-Binding Domains of the Dynein Motor

(2012) Julie Huang et al.   CELL

The 2.8 Å crystal structure of the dynein motor domain

(2012) Takahide Kon et al.   NATURE

Multiple modes of cytoplasmic dynein regulation

(2012) Richard B. Vallee et al.   NATURE CELL BIOLOGY

Insights into dynein motor domain function from a 3.3-Å crystal structure

(2012) Helgo Schmidt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dynein achieves processive motion using both stochastic and coordinated stepping

(2012) Weihong Qiu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ideal, catch, and slip bonds in cadherin adhesion

(2012) S. Rakshit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Microtubule Binding and Release by Dynein

(2012) W. B. Redwine et al.   SCIENCE

Mechanical stochastic tug-of-war models cannot explain bidirectional lipid-droplet transport

(2011) A. Kunwar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytoplasmic Dynein Moves Through Uncoordinated Stepping of the AAA+ Ring Domains

(2011) M. A. DeWitt et al.   SCIENCE

Coordination of molecular motors: from in vitro assays to intracellular dynamics

(2010) Erika LF Holzbaur et al.   CURRENT OPINION IN CELL BIOLOGY

Contribution of the myosin VI tail domain to processive stepping and intramolecular tension sensing

(2010) Alexander R. Dunn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulators of the cytoplasmic dynein motor

(2009) Julia R. Kardon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Helix sliding in the stalk coiled coil of dynein couples ATPase and microtubule binding

(2009) Takahide Kon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Direct measurements of kinesin torsional properties reveal flexible domains and occasional stalk reversals during stepping

(2009) B. Gutierrez-Medina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Catch Bonds in Adhesion

(2008) Wendy Thomas   Annual Review of Biomedical Engineering

Biophysics of Catch Bonds

(2008) Wendy E. Thomas et al.   Annual Review of Biophysics

Intramolecular Strain Coordinates Kinesin Stepping Behavior along Microtubules

(2008) Ahmet Yildiz et al.   CELL

FimH Forms Catch Bonds That Are Enhanced by Mechanical Force Due to Allosteric Regulation

(2008) Olga Yakovenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulatory ATPase Sites of Cytoplasmic Dynein Affect Processivity and Force Generation

(2008) Carol Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Theory, analysis, and interpretation of single-molecule force spectroscopy experiments

(2008) O. K. Dudko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Load-dependent ADP binding to myosins V and VI: Implications for subunit coordination and function

(2008) Y. Oguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Functional Role of Dynein's Microtubule-Binding Domain

(2008) A. P. Carter et al.   SCIENCE