The Integrated Landscape of Biological Candidate Causal Genes in Coronary Artery Disease

A practical view of fine-mapping and gene prioritization in the post-genome-wide association era

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Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association

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Genetics of Common, Complex Coronary Artery Disease

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Integrated analysis of gene expression changes associated with coronary artery disease

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A decade of genome-wide association studies for coronary artery disease: the challenges ahead

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Projected Costs of Informal Caregiving for Cardiovascular Disease: 2015 to 2035: A Policy Statement From the American Heart Association

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From genome-wide associations to candidate causal variants by statistical fine-mapping

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Estimation of complex effect-size distributions using summary-level statistics from genome-wide association studies across 32 complex traits

(2018) Yan Zhang et al.   NATURE GENETICS

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The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019

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Calcineurin signaling in the heart: The importance of time and place

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Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

(2017) Thomas R. Webb et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease

(2017) Derek Klarin et al.   NATURE GENETICS

Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms

(2017) Joanna M M Howson et al.   NATURE GENETICS

Association analyses based on false discovery rate implicate new loci for coronary artery disease

(2017) Christopher P Nelson et al.   NATURE GENETICS

Genetics of coronary artery disease: discovery, biology and clinical translation

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GWAB: a web server for the network-based boosting of human genome-wide association data

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Attenuated Superoxide Dismutase 2 Activity Induces Atherosclerotic Plaque Instability During Aging in Hyperlipidemic Mice

(2017) Aleksandr E. Vendrov et al.   Journal of the American Heart Association

The AGE-RAGE Axis: Implications for Age-Associated Arterial Diseases

(2017) Laura M. Senatus et al.   Frontiers in Genetics

Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease

(2017) Pim van der Harst et al.   CIRCULATION RESEARCH

Network-Based Identification and Prioritization of Key Regulators of Coronary Artery Disease LociSignificance

(2016) Yuqi Zhao et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Shared Risk Factors in Cardiovascular Disease and Cancer

(2016) Ryan J. Koene et al.   CIRCULATION

Genetics of Coronary Artery Disease

(2016) Ruth McPherson et al.   CIRCULATION RESEARCH

CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis

(2016) Yoko Kojima et al.   NATURE

Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets

(2016) Zhihong Zhu et al.   NATURE GENETICS

Integrative approaches for large-scale transcriptome-wide association studies

(2016) Alexander Gusev et al.   NATURE GENETICS

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

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The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci

(2016) Clint L. Miller et al.   Nature Communications

Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits

(2016) Jennifer M. Whitehead Pavlides et al.   Genome Medicine

The Role of AGE/RAGE Signaling in Diabetes-Mediated Vascular Calcification

(2016) Amber M. Kay et al.   Journal of Diabetes Research

Prediction of Causal Candidate Genes in Coronary Artery Disease LociSignificance

(2015) Ingrid Brænne et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery DiseaseSignificance

(2015) Sujoy Ghosh et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk FactorsNovelty and Significance

(2015) Marissa LeBlanc et al.   CIRCULATION RESEARCH

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

Understanding multicellular function and disease with human tissue-specific networks

(2015) Casey S Greene et al.   NATURE GENETICS

The anatomical distribution of genetic associations

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Biological interpretation of genome-wide association studies using predicted gene functions

(2015) Tune H. Pers et al.   Nature Communications

Shared Molecular Pathways and Gene Networks for Cardiovascular Disease and Type 2 Diabetes Mellitus in Women Across Diverse Ethnicities

(2014) K. H. K. Chan et al.   Circulation-Cardiovascular Genetics

Obesity-associated variants within FTO form long-range functional connections with IRX3

(2014) Scott Smemo et al.   NATURE

Genetic and epigenetic fine mapping of causal autoimmune disease variants

(2014) Kyle Kai-How Farh et al.   NATURE

Selecting causal genes from genome-wide association studies via functionally coherent subnetworks

(2014) Murat Taşan et al.   NATURE METHODS

VEGAS2: Software for More Flexible Gene-Based Testing

(2014) Aniket Mishra et al.   Twin Research and Human Genetics

Sherlock: Detecting Gene-Disease Associations by Matching Patterns of Expression QTL and GWAS

(2013) Xin He et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Vascular Extracellular Matrix in Atherosclerosis

(2013) Dimitry A. Chistiakov et al.   Cardiology in Review

Network-assisted analysis to prioritize GWAS results: principles, methods and perspectives

(2013) Peilin Jia et al.   HUMAN GENETICS

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(2013) Fabian Sanchis-Gomar et al.   MOLECULAR MEDICINE

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(2013) Hiroto Ueba et al.   MOLECULAR MEDICINE

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Systematic identification of trans eQTLs as putative drivers of known disease associations

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Candidate disease gene prediction usingGentrepid: application to a genome-wide association study on coronary artery disease

(2013) Sara Ballouz et al.   Molecular Genetics & Genomic Medicine

The role of calpains in myocardial remodelling and heart failure

(2012) E. Letavernier et al.   CARDIOVASCULAR RESEARCH

Inheritance of coronary artery disease in men: an analysis of the role of the Y chromosome

(2012) Fadi J Charchar et al.   LANCET

Network-Assisted Investigation of Combined Causal Signals from Genome-Wide Association Studies in Schizophrenia

(2012) Peilin Jia et al.   PLoS Computational Biology

Mitochondrial Oxidative Stress in Aortic Stiffening With Age

(2011) Rui-Hai Zhou et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Association of C47T polymorphism in SOD2 gene with coronary artery disease: a case–control study and a meta-analysis

(2011) Changwei Tian et al.   MOLECULAR BIOLOGY REPORTS

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

(2011) Heribert Schunkert et al.   NATURE GENETICS

Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology

(2011) Elizabeth J. Rossin et al.   PLoS Genetics

Erythropoietin in Patients With Acute Coronary Syndrome and Its Cardioprotective Action After Percutaneous Coronary Intervention

(2009) Reo Nakamura et al.   CIRCULATION JOURNAL

The V16A polymorphism in SOD2 is associated with increased risk of diabetic nephropathy and cardiovascular disease in type 1 diabetes

(2009) A. Möllsten et al.   DIABETOLOGIA

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

(2009) J. Chen et al.   NUCLEIC ACIDS RESEARCH

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH