The Role of the Gut Microbiome in Energy Balance With a Focus on the Gut-Adipose Tissue Axis

Microbiota Depletion Impairs Thermogenesis of Brown Adipose Tissue and Browning of White Adipose Tissue

(2019) Baoguo Li et al.   Cell Reports

Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases

(2019) Serena Sanna et al.   NATURE GENETICS

Resveratrol-induced gut microbiota reduces obesity in high-fat diet-fed mice

(2019) Pan Wang et al.   INTERNATIONAL JOURNAL OF OBESITY

Supplementation with Sodium Butyrate Modulates the Composition of the Gut Microbiota and Ameliorates High-Fat Diet-Induced Obesity in Mice

(2019) Wanjun Fang et al.   JOURNAL OF NUTRITION

Donor metabolic characteristics drive effects of faecal microbiota transplantation on recipient insulin sensitivity, energy expenditure and intestinal transit time

(2019) Pieter de Groot et al.   GUT

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study

(2019) Clara Depommier et al.   NATURE MEDICINE

The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs

(2019) Anthony T. Virtue et al.   Science Translational Medicine

Gut Microbiota Composition Is Associated With the Global DNA Methylation Pattern in Obesity

(2019) Bruno Ramos-Molina et al.   Frontiers in Genetics

The microbiota–gut–brain interaction in regulating host metabolic adaptation to cold in male Brandt’s voles (Lasiopodomys brandtii)

(2019) Ting-Bei Bo et al.   ISME Journal

Gut microbiota confers host resistance to obesity by metabolizing dietary polyunsaturated fatty acids

(2019) Junki Miyamoto et al.   Nature Communications

The gut microbiome and elevated cardiovascular risk in obesity and autoimmunity

(2018) Lora J. Kasselman et al.   ATHEROSCLEROSIS

Small Intestine Microbiota Regulate Host Digestive and Absorptive Adaptive Responses to Dietary Lipids

(2018) Kristina Martinez-Guryn et al.   Cell Host & Microbe

Sodium butyrate supplementation ameliorates diabetic inflammation in db/db mice

(2018) Youhua Xu et al.   JOURNAL OF ENDOCRINOLOGY

Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes

(2018) Liping Zhao et al.   SCIENCE

A metagenomic approach to dissect the genetic composition of enterotypes in Han Chinese and two Muslim groups

(2018) Jing Li et al.   SYSTEMATIC AND APPLIED MICROBIOLOGY

Vanillic acid activates thermogenesis in brown and white adipose tissue

(2018) Xue Han et al.   Food & Function

Involvement of gut microbiome in human health and disease: brief overview, knowledge gaps and research opportunities

(2018) Dachao Liang et al.   Gut Pathogens

Factors Affecting Gastrointestinal Microbiome Development in Neonates

(2018) Clara Chong et al.   Nutrients

Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice

(2018) David Ma et al.   Scientific Reports

Differential metabolic effects of oral butyrate treatment in lean versus metabolic syndrome subjects

(2018) KEC Bouter et al.   Clinical and Translational Gastroenterology

Absolute quantitation of microbiota abundance in environmental samples

(2018) Andrzej Tkacz et al.   Microbiome

Resveratrol-Induced White Adipose Tissue Browning in Obese Mice by Remodeling Fecal Microbiota

(2018) Weiyao Liao et al.   MOLECULES

A sensitive GC/MS detection method for analyzing microbial metabolites short chain fatty acids in fecal and serum samples

(2018) Shuming Zhang et al.   TALANTA

10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, enhances energy metabolism by activation of TRPV1

(2017) Minji Kim et al.   FASEB JOURNAL

Butyrate reduces appetite and activates brown adipose tissue via the gut-brain neural circuit

(2017) Zhuang Li et al.   GUT

Ketone bodies mimic the life span extending properties of caloric restriction

(2017) Richard L. Veech et al.   IUBMB LIFE

Resveratrol supplementation of high-fat diet-fed pregnant mice promotes brown and beige adipocyte development and prevents obesity in male offspring

(2017) Tiande Zou et al.   JOURNAL OF PHYSIOLOGY-LONDON

Consumption of Two Healthy Dietary Patterns Restored Microbiota Dysbiosis in Obese Patients with Metabolic Dysfunction

(2017) Carmen Haro et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis

(2017) Anna Worthmann et al.   NATURE MEDICINE

High-cholesterol diet does not alter gut microbiota composition in mice

(2017) Lidiya G. Dimova et al.   Nutrition & Metabolism

The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue

(2017) Rebecca C. Schugar et al.   Cell Reports

Reduced Mass and Diversity of the Colonic Microbiome in Patients with Multiple Sclerosis and Their Improvement with Ketogenic Diet

(2017) Alexander Swidsinski et al.   Frontiers in Microbiology

Next-Generation Beneficial Microbes: The Case of Akkermansia muciniphila

(2017) Patrice D. Cani et al.   Frontiers in Microbiology

Gut Microbiota-Dependent Metabolite Trimethylamine N-Oxide Contributes to Cardiac Dysfunction in Western Diet-Induced Obese Mice

(2017) Kui Chen et al.   Frontiers in Physiology

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

(2016) Weifei Zhu et al.   CELL

The Host Shapes the Gut Microbiota via Fecal MicroRNA

(2016) Shirong Liu et al.   Cell Host & Microbe

Altered Microbiota Contributes to Reduced Diet-Induced Obesity upon Cold Exposure

(2016) Marika Ziętak et al.   Cell Metabolism

Correlation between body mass index and faecal microbiota from children

(2016) A. Ignacio et al.   CLINICAL MICROBIOLOGY AND INFECTION

Improved Glucose Homeostasis in Obese Mice Treated With Resveratrol Is Associated With Alterations in the Gut Microbiome

(2016) Miranda M. Sung et al.   DIABETES

Two Healthy Diets Modulate Gut Microbial Community Improving Insulin Sensitivity in a Human Obese Population

(2016) Carmen Haro et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Diet-Microbiota Interactions Mediate Global Epigenetic Programming in Multiple Host Tissues

(2016) Kimberly A. Krautkramer et al.   MOLECULAR CELL

A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

(2016) Hubert Plovier et al.   NATURE MEDICINE

Signals from the gut microbiota to distant organs in physiology and disease

(2016) Bjoern O Schroeder et al.   NATURE MEDICINE

Diet, microorganisms and their metabolites and colon cancer

(2016) Stephen J. D. O'Keefe   Nature Reviews Gastroenterology & Hepatology

The healthy human microbiome

(2016) Jason Lloyd-Price et al.   Genome Medicine

10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, potently activates PPARγ and stimulates adipogenesis

(2015) Tsuyoshi Goto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Activated Type 2 Innate Lymphoid Cells Regulate Beige Fat Biogenesis

(2015) Min-Woo Lee et al.   CELL

Gut Microbiota Orchestrates Energy Homeostasis during Cold

(2015) Claire Chevalier et al.   CELL

Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation

(2015) Valentina Tremaroli et al.   Cell Metabolism

Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling

(2015) Robert Caesar et al.   Cell Metabolism

Akkermansia muciniphilaand improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology

(2015) Maria Carlota Dao et al.   GUT

Resveratrol induces brown-like adipocyte formation in white fat through activation of AMP-activated protein kinase (AMPK) α1

(2015) S Wang et al.   INTERNATIONAL JOURNAL OF OBESITY

Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis

(2015) Labros Sidossis et al.   JOURNAL OF CLINICAL INVESTIGATION

Microbiota depletion promotes browning of white adipose tissue and reduces obesity

(2015) Nicolas Suárez-Zamorano et al.   NATURE MEDICINE

Role of the normal gut microbiota

(2015) Sai Manasa Jandhyala   WORLD JOURNAL OF GASTROENTEROLOGY

Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota

(2015) Lucie Geurts et al.   Nature Communications

Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice

(2015) Marc Schneeberger et al.   Scientific Reports

Metabolic Regulation of Immune Responses

(2014) Kirthana Ganeshan et al.   Annual Review of Immunology

Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat

(2014) Yifu Qiu et al.   CELL

γ-Butyrobetaine Is a Proatherogenic Intermediate in Gut Microbial Metabolism of L -Carnitine to TMAO

(2014) Robert A. Koeth et al.   Cell Metabolism

Role of Monocarboxylate Transporters in Drug Delivery to the Brain

(2014) Nisha Vijay et al.   CURRENT PHARMACEUTICAL DESIGN

Temperature-Acclimated Brown Adipose Tissue Modulates Insulin Sensitivity in Humans

(2014) Paul Lee et al.   DIABETES

A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increasedAkkermansiaspp. population in the gut microbiota of mice

(2014) Fernando F Anhê et al.   GUT

Dietary trimethylamine N-oxide exacerbates impaired glucose tolerance in mice fed a high fat diet

(2014) Xiang Gao et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Short-Chain Fatty Acids Enhance Adipocyte Differentiation in the Stromal Vascular Fraction of Porcine Adipose Tissue

(2014) Genlai Li et al.   JOURNAL OF NUTRITION

The different shades of fat

(2014) Vivian Peirce et al.   NATURE

ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes

(2014) S. Ussar et al.   Science Translational Medicine

Gut Microbiota as an Epigenetic Regulator: Pilot Study Based on Whole-Genome Methylation Analysis

(2014) Himanshu Kumar et al.   mBio

Differential Modulation by Akkermansia muciniphila and Faecalibacterium prausnitzii of Host Peripheral Lipid Metabolism and Histone Acetylation in Mouse Gut Organoids

(2014) S. Lukovac et al.   mBio

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

(2014) Gary Frost et al.   Nature Communications

Effects of resveratrol on gut microbiota and fat storage in a mouse model with high-fat-induced obesity

(2014) Yi Qiao et al.   Food & Function

Ketogenic Diet for Obesity: Friend or Foe?

(2014) Antonio Paoli   International Journal of Environmental Research and Public Health

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

(2013) Sama I. Sayin et al.   Cell Metabolism

Influence of bacteria on epigenetic gene control

(2013) Kyoko Takahashi   CELLULAR AND MOLECULAR LIFE SCIENCES

Effects of short chain fatty acid producing bacteria on epigenetic regulation of FFAR3 in type 2 diabetes and obesity

(2013) Marlene Remely et al.   GENE

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

(2013) Gijs den Besten et al.   JOURNAL OF LIPID RESEARCH

Dietary intervention impact on gut microbial gene richness

(2013) Aurélie Cotillard et al.   NATURE

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

Blunted metabolic responses to cold and insulin stimulation in brown adipose tissue of obese humans

(2013) Janne Orava et al.   Obesity

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

(2013) V. K. Ridaura et al.   SCIENCE

The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43

(2013) Ikuo Kimura et al.   Nature Communications

Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome

(2012) Anne Vrieze et al.   GASTROENTEROLOGY

The Microbiota of the Gut in Preschool Children With Normal and Excessive Body Weight

(2012) Caroline L.J. Karlsson et al.   Obesity

Frequency of Firmicutes and Bacteroidetes in gut microbiota in obese and normal weight Egyptian children and adults

(2011) Nagwa Abdallah Ismail et al.   Archives of Medical Science

High Fat Intake Leads to Acute Postprandial Exposure to Circulating Endotoxin in Type 2 Diabetic Subjects

(2011) A. L. Harte et al.   DIABETES CARE

Epigenetic Control of the Host Gene by Commensal Bacteria in Large Intestinal Epithelial Cells

(2011) Kyoko Takahashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thermogenic Activation Induces FGF21 Expression and Release in Brown Adipose Tissue

(2011) Elayne Hondares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Comparative effects of very low-carbohydrate, high-fat and high-carbohydrate, low-fat weight-loss diets on bowel habit and faecal short-chain fatty acids and bacterial populations

(2009) Grant D. Brinkworth et al.   BRITISH JOURNAL OF NUTRITION

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice

(2009) Z. Gao et al.   DIABETES

Microbiota and SCFA in Lean and Overweight Healthy Subjects

(2009) Andreas Schwiertz et al.   Obesity

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   OBSTETRICAL & GYNECOLOGICAL SURVEY

Human gut microbiota in obesity and after gastric bypass

(2009) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

(2009) P. J. Turnbaugh et al.   Science Translational Medicine

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

(2008) Peter J. Turnbaugh et al.   Cell Host & Microbe

Human colonic microbiota associated with diet, obesity and weight loss

(2008) S H Duncan et al.   INTERNATIONAL JOURNAL OF OBESITY

Fifty years of advances in bile acid synthesis and metabolism

(2008) David W. Russell   JOURNAL OF LIPID RESEARCH

Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon

(2008) Markus Waldecker et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

A core gut microbiome in obese and lean twins

(2008) Peter J. Turnbaugh et al.   NATURE