Optimized serial expansion of human induced pluripotent stem cells using low‐density inoculation to generate clinically relevant quantities in vertical‐wheel bioreactors

Treatment of Parkinson’s Disease through Personalized Medicine and Induced Pluripotent Stem Cells

(2019) Theo Stoddard-Bennett et al.   Cells

Strategies for the expansion of human induced pluripotent stem cells as aggregates in single-use Vertical-Wheel™ bioreactors

(2019) Diogo E. S. Nogueira et al.   Journal of Biological Engineering

Using computational fluid dynamics (CFD) modeling to understand murine embryonic stem cell aggregate size and pluripotency distributions in stirred suspension bioreactors

(2019) Breanna S. Borys et al.   JOURNAL OF BIOTECHNOLOGY

Scale-up of embryonic stem cell aggregate stirred suspension bioreactor culture enabled by computational fluid dynamics modeling

(2018) Breanna S. Borys et al.   BIOCHEMICAL ENGINEERING JOURNAL

Scalable culture of human induced pluripotent cells on microcarriers under xeno-free conditions using single-use vertical-wheel™ bioreactors

(2018) Carlos AV Rodrigues et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Recent Trends in Research with Human Pluripotent Stem Cells: Impact of Research and Use of Cell Lines in Experimental Research and Clinical Trials

(2018) Anke Guhr et al.   Stem Cell Reports

Human Pluripotent Stem Cell Culture: Current Status, Challenges, and Advancement

(2018) Sushrut Dakhore et al.   Stem Cells International

Natural Killer Cell-Based Immunotherapy for Cancer: Advances and Prospects

(2018) Yuan Hu et al.   Engineering

Expansion of 3D human induced pluripotent stem cell aggregates in bioreactors: Bioprocess intensification and scaling-up approaches

(2017) Bernardo Abecasis et al.   JOURNAL OF BIOTECHNOLOGY

Scalable stirred suspension culture for the generation of billions of human induced pluripotent stem cells using single-use bioreactors

(2017) Chee Keong Kwok et al.   Journal of Tissue Engineering and Regenerative Medicine

Characterization of 3D pluripotent stem cell aggregates and the impact of their properties on bioprocessing

(2017) Sébastien Sart et al.   PROCESS BIOCHEMISTRY

Progress and challenges in large-scale expansion of human pluripotent stem cells

(2017) Christina Kropp et al.   PROCESS BIOCHEMISTRY

Optimizing Human Induced Pluripotent Stem Cell Expansion in Stirred-Suspension Culture

(2017) Guoliang Meng et al.   STEM CELLS AND DEVELOPMENT

Microcarrier-based platforms for in vitro expansion and differentiation of human pluripotent stem cells in bioreactor culture systems

(2016) Sara M. Badenes et al.   JOURNAL OF BIOTECHNOLOGY

How iPS cells changed the world

(2016) Megan Scudellari   NATURE

Induced pluripotent stem cell technology: a decade of progress

(2016) Yanhong Shi et al.   NATURE REVIEWS DRUG DISCOVERY

Pluripotent stem cells progressing to the clinic

(2016) Alan Trounson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A reproducible and versatile system for the dynamic expansion of human pluripotent stem cells in suspension

(2015) Andreas Elanzew et al.   Biotechnology Journal

Production of oncolytic adenovirus and human mesenchymal stem cells in a single-use, Vertical-Wheel bioreactor system: Impact of bioreactor design on performance of microcarrier-based cell culture processes

(2015) Marcos F. Q. Sousa et al.   BIOTECHNOLOGY PROGRESS

Hurdles to clinical translation of human induced pluripotent stem cells

(2015) Evgenios Neofytou et al.   JOURNAL OF CLINICAL INVESTIGATION

Current advances in the generation of human iPS cells: implications in cell-based regenerative medicine

(2015) Ana Revilla et al.   Journal of Tissue Engineering and Regenerative Medicine

A reproducible and versatile system for the dynamic expansion of human pluripotent stem cells in suspension

(2015) Andreas Elanzew et al.   Biotechnology Journal

Human pluripotent stem cell-derived products: Advances towards robust, scalable and cost-effective manufacturing strategies

(2014) Michael J. Jenkins et al.   Biotechnology Journal

An intermittent rocking platform for integrated expansion and differentiation of human pluripotent stem cells to cardiomyocytes in suspended microcarrier cultures

(2014) Sherwin Ting et al.   Stem Cell Research

A 3D Sphere Culture System Containing Functional Polymers for Large-Scale Human Pluripotent Stem Cell Production

(2014) Tomomi G. Otsuji et al.   Stem Cell Reports

Maximizing mouse embryonic stem cell production in a stirred tank reactor by controlling dissolved oxygen concentration and continuous perfusion operation

(2013) Ana Fernandes-Platzgummer et al.   BIOCHEMICAL ENGINEERING JOURNAL

Induced pluripotent stem cells in medicine and biology

(2013) K. Takahashi et al.   DEVELOPMENT

Stem cell engineering in bioreactors for large-scale bioprocessing

(2013) Ning Liu et al.   ENGINEERING IN LIFE SCIENCES

Simple suspension culture system of human iPS cells maintaining their pluripotency for cardiac cell sheet engineering

(2013) Yuji Haraguchi et al.   Journal of Tissue Engineering and Regenerative Medicine

Scalable expansion of human induced pluripotent stem cells in the defined xeno-free E8 medium under adherent and suspension culture conditions

(2013) Ying Wang et al.   Stem Cell Research

Bioprocess Development for Mass Production of Size-Controlled Human Pluripotent Stem Cell Aggregates in Stirred Suspension Bioreactor

(2012) Saeed Abbasalizadeh et al.   TISSUE ENGINEERING PART C-METHODS

Suspension Culture of Human Pluripotent Stem Cells in Controlled, Stirred Bioreactors

(2012) Ruth Olmer et al.   TISSUE ENGINEERING PART C-METHODS

Process engineering of human pluripotent stem cells for clinical application

(2012) Margarida Serra et al.   TRENDS IN BIOTECHNOLOGY

Stem cell cultivation in bioreactors

(2011) Carlos A.V. Rodrigues et al.   BIOTECHNOLOGY ADVANCES

Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency

(2011) Frederick Anokye-Danso et al.   Cell Stem Cell

Expansion and long-term maintenance of induced pluripotent stem cells in stirred suspension bioreactors

(2011) Mehdi Shafa et al.   Journal of Tissue Engineering and Regenerative Medicine

Scalable expansion of human pluripotent stem cells in suspension culture

(2011) Robert Zweigerdt et al.   Nature Protocols

Derivation, propagation and controlled differentiation of human embryonic stem cells in suspension

(2010) Debora Steiner et al.   NATURE BIOTECHNOLOGY