Dynorphin activation of kappa opioid receptor promotes microglial polarization toward M2 phenotype via TLR4/NF-κB pathway

Effects of Betaine on LPS-Stimulated Activation of Microglial M1/M2 Phenotypes by Suppressing TLR4/NF-κB Pathways in N9 Cells

(2019) Hui Shi et al.   MOLECULES

Curcumin inhibits LPS-induced neuroinflammation by promoting microglial M2 polarization via TREM2/ TLR4/ NF-κB pathways in BV2 cells

(2019) Jiawei Zhang et al.   MOLECULAR IMMUNOLOGY

The novel estrogenic receptor GPR30 alleviates ischemic injury by inhibiting TLR4-mediated microglial inflammation

(2018) Zengli Zhang et al.   Journal of Neuroinflammation

Noninflammatory Changes of Microglia Are Sufficient to Cause Epilepsy

(2018) Xiaofeng Zhao et al.   Cell Reports

Microglia after Seizures and in Epilepsy

(2018) Toshimitsu Hiragi et al.   Cells

Inhibition of MyD88 Signaling Skews Microglia/Macrophage Polarization and Attenuates Neuronal Apoptosis in the Hippocampus After Status Epilepticus in Mice

(2018) Jin-Tao Liu et al.   Neurotherapeutics

Dynorphin activation of kappa opioid receptor protects against epilepsy and seizure-induced brain injury via PI3K/Akt/Nrf2/HO-1 pathway

(2018) Hongmei Dai et al.   CELL CYCLE

Brain expression of inflammatory mediators in Mesial Temporal Lobe Epilepsy patients

(2017) Bárbara Leal et al.   JOURNAL OF NEUROIMMUNOLOGY

Role of Atypical Chemokine Receptors in Microglial Activation and Polarization

(2017) Valentina Salvi et al.   Frontiers in Aging Neuroscience

MFG-E8 Selectively Inhibited Aβ-Induced Microglial M1 Polarization via NF-κB and PI3K-Akt Pathways

(2016) Xiaolei Shi et al.   MOLECULAR NEUROBIOLOGY

Antidepressant therapies inhibit inflammation and microglial M1-polarization

(2016) Hans O. Kalkman et al.   PHARMACOLOGY & THERAPEUTICS

Safflower Yellow regulates microglial polarization and inhibits inflammatory response in LPS-stimulated Bv2 cells

(2015) Xing-Wang Yang et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

The Inhibitory Effects of Npas4 on Seizures in Pilocarpine-Induced Epileptic Rats

(2014) Dan Wang et al.   PLoS One

κ-Opioid receptor stimulation modulates TLR4/NF-κB signaling in the rat heart subjected to ischemia–reperfusion

(2013) JiaJi Lin et al.   CYTOKINE

Neuroprotective function for ramified microglia in hippocampal excitotoxicity

(2012) Jonathan Vinet et al.   Journal of Neuroinflammation

Pituitary adenylate cyclase-activating polypeptide (PACAP) is an upstream regulator of prodynorphin mRNA expression in neurons

(2010) Ying Xu Dong et al.   NEUROSCIENCE LETTERS

Dynamic up-regulation of prodynorphin transcription in temporal lobe epilepsy

(2009) Susanne Pirker et al.   HIPPOCAMPUS

30 years of dynorphins — New insights on their functions in neuropsychiatric diseases

(2009) Christoph Schwarzer   PHARMACOLOGY & THERAPEUTICS