The novel estrogenic receptor GPR30 alleviates ischemic injury by inhibiting TLR4-mediated microglial inflammation

The effect of minocycline on indolamine 2, 3 dioxygenase expression and the levels of kynurenic acid and quinolinic acid in LPS-activated primary rat microglia

(2018) Zahra Bahrami et al.   CYTOKINE

Emerging roles for the novel estrogen-sensing receptor GPER1 in the CNS

(2017) Amy Alexander et al.   NEUROPHARMACOLOGY

Activation of G protein-coupled estrogen receptor 1 (GPER-1) ameliorates blood-brain barrier permeability after global cerebral ischemia in ovariectomized rats

(2016) Dan Lu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

G-1 exerts neuroprotective effects through G protein-coupled estrogen receptor 1 following spinal cord injury in mice

(2016) Q. Cheng et al.   BIOSCIENCE REPORTS

Estrogens, Neuroinflammation, and Neurodegeneration

(2016) Alessandro Villa et al.   ENDOCRINE REVIEWS

A novel form of synaptic plasticity in field CA3 of hippocampus requires GPER1 activation and BDNF release

(2015) Victor Briz et al.   JOURNAL OF CELL BIOLOGY

G-Protein-Coupled Estrogen Receptor 1 Is Anatomically Positioned to Modulate Synaptic Plasticity in the Mouse Hippocampus

(2015) E. M. Waters et al.   JOURNAL OF NEUROSCIENCE

G-protein-coupled receptor 30-mediated antiapoptotic effect of estrogen on spinal motor neurons following injury and its underlying mechanisms

(2015) JINGYU CHEN et al.   Molecular Medicine Reports

Estrogen receptor-mediated resveratrol actions on blood-brain barrier of ovariectomized mice

(2015) Jin A. Shin et al.   NEUROBIOLOGY OF AGING

Neuroprotection in Parkinsonian-treated mice via estrogen receptor α activation requires G protein-coupled estrogen receptor 1

(2015) Mélanie Bourque et al.   NEUROPHARMACOLOGY

Proline-, glutamic acid-, and leucine-rich protein 1 mediates estrogen rapid signaling and neuroprotection in the brain

(2015) Gangadhara R. Sareddy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GPR30 mediates estrogen rapid signaling and neuroprotection

(2014) Hui Tang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Sex-Dependent Effects of G Protein–Coupled Estrogen Receptor Activity on Outcome After Ischemic Stroke

(2014) Brad R.S. Broughton et al.   STROKE

Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling

(2014) Lin Luo et al.   Nature Communications

Toll-Like Receptor 4-Dependent Microglial Activation Mediates Spinal Cord Ischemia-Reperfusion Injury

(2013) M. T. Bell et al.   CIRCULATION

Menopausal Hormone Therapy and Health Outcomes During the Intervention and Extended Poststopping Phases of the Women’s Health Initiative Randomized Trials

(2013) JoAnn E. Manson et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Regulation of Hypoxia-Induced Inflammatory Responses and M1-M2 Phenotype Switch of Primary Rat Microglia by Sex Steroids

(2013) Pardes Habib et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Estrogen Mediates Neuroprotection and Anti-Inflammatory Effects during EAE through ER  Signaling on Astrocytes But Not through ER  Signaling on Astrocytes or Neurons

(2013) R. D. Spence et al.   JOURNAL OF NEUROSCIENCE

17β-Estradiol Confers Protection after Traumatic Brain Injury in the Rat and Involves Activation of G Protein-Coupled Estrogen Receptor 1

(2013) Nicole L. Day et al.   JOURNAL OF NEUROTRAUMA

Estrogen-Induced Nongenomic Calcium Signaling Inhibits Lipopolysaccharide-Stimulated Tumor Necrosis Factor α Production in Macrophages

(2013) Limin Liu et al.   PLoS One

Minireview: G Protein-Coupled Estrogen Receptor-1, GPER-1: Its Mechanism of Action and Role in Female Reproductive Cancer, Renal and Vascular Physiology

(2012) Edward J. Filardo et al.   ENDOCRINOLOGY

Inflammatory Cytokines in Experimental and Human Stroke

(2012) Kate Lykke Lambertsen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

G-Protein-Coupled Receptor 30 Mediates Rapid Neuroprotective Effects of Estrogen via Depression of NR2B-Containing NMDA Receptors

(2012) S.-b. Liu et al.   JOURNAL OF NEUROSCIENCE

GPER1/GPR30 Activation Improves Neuronal Survival Following Global Cerebral Ischemia Induced by Cardiac Arrest in Mice

(2012) Y. Kosaka et al.   Translational Stroke Research

The G-protein-coupled estrogen receptor GPER in health and disease

(2011) Eric R. Prossnitz et al.   Nature Reviews Endocrinology

GPR30/GPER-1 mediates rapid decreases in TLR4 expression on murine macrophages

(2010) Jennifer A. Rettew et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Ras-related protein Rab10 facilitates TLR4 signaling by promoting replenishment of TLR4 onto the plasma membrane

(2010) D. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estrogen anti-inflammatory activity in brain: A therapeutic opportunity for menopause and neurodegenerative diseases

(2008) Elisabetta Vegeto et al.   FRONTIERS IN NEUROENDOCRINOLOGY

The APOE4 genotype alters the response of microglia and macrophages to 17β-estradiol

(2007) Candice M. Brown et al.   NEUROBIOLOGY OF AGING