Methylene Homologues of Artemisone: An Unexpected Structure-Activity Relationship and a Possible Implication for the Design of C10-Substituted Artemisinins

Stability of the Antimalarial Drug Dihydroartemisinin under Physiologically Relevant Conditions: Implications for Clinical Treatment and Pharmacokinetic andIn VitroAssays

(2015) Silvia Parapini et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The survival times of malaria-infected mice are prolonged more by several new two-carbon-linked artemisinin-derived dimer carbamates than by the trioxane antimalarial drug artemether

(2014) Ryan C. Conyers et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Artemisinin resistance – modelling the potential human and economic costs

(2014) Yoel Lubell et al.   MALARIA JOURNAL

Anticancer Properties of Distinct Antimalarial Drug Classes

(2014) Rob Hooft van Huijsduijnen et al.   PLoS One

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

(2013) Frédéric Ariey et al.   NATURE

Glucocorticosteroids in Nano-Sterically Stabilized Liposomes Are Efficacious for Elimination of the Acute Symptoms of Experimental Cerebral Malaria

(2013) Judith H. Waknine-Grinberg et al.   PLoS One

ComparativeEx VivoActivity of Novel Endoperoxides in Multidrug-Resistant Plasmodium falciparum and P. vivax

(2012) Jutta Marfurt et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Interactions between Artemisinins and other Antimalarial Drugs in Relation to the Cofactor Model-A Unifying Proposal for Drug Action

(2012) Richard K. Haynes et al.   ChemMedChem

Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study

(2012) Aung Pyae Phyo et al.   LANCET

The Activities of Current Antimalarial Drugs on the Life Cycle Stages of Plasmodium: A Comparative Study with Human and Rodent Parasites

(2012) Michael Delves et al.   PLOS MEDICINE

Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration

(2011) Carrie A Morris et al.   MALARIA JOURNAL

In vitro study of the anti-cancer effects of artemisone alone or in combination with other chemotherapeutic agents

(2010) Andrew M. Gravett et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Facile Oxidation of Leucomethylene Blue and Dihydroflavins by Artemisinins: Relationship with Flavoenzyme Function and Antimalarial Mechanism of Action

(2010) Richard K. Haynes et al.   ChemMedChem

Reactions of Antimalarial Peroxides with Each of Leucomethylene Blue and Dihydroflavins: Flavin Reductase and the Cofactor Model Exemplified

(2010) Richard K. Haynes et al.   ChemMedChem

The pharmaceutical death-ride of dihydroartemisinin

(2010) Frans Jansen   MALARIA JOURNAL

Artemisone effective against murine cerebral malaria

(2010) Judith H Waknine-Grinberg et al.   MALARIA JOURNAL

Artemisone and Artemiside Control Acute and Reactivated Toxoplasmosis in a Murine Model

(2009) I. R. Dunay et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evaluation of Artemisone Combinations in Aotus Monkeys Infected with Plasmodium falciparum

(2009) N. Obaldia et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Dihydroartemisinin improves the efficiency of chemotherapeutics in lung carcinomas in vivo and inhibits murine Lewis lung carcinoma cell line growth in vitro

(2009) Hui-Jun Zhou et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Fre Is the Major Flavin Reductase Supporting Bioluminescence fromVibrio harveyiLuciferase inEscherichia coli

(2009) Zachary T. Campbell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New medicines to improve control and contribute to the eradication of malaria

(2009) Timothy N. C. Wells et al.   NATURE REVIEWS DRUG DISCOVERY

Computational and experimental studies on the catalytic mechanism of biliverdin-IXβ reductase

(2008) Liam J. Smith et al.   BIOCHEMICAL JOURNAL

Artemisinins: their growing importance in medicine

(2008) Sanjeev Krishna et al.   TRENDS IN PHARMACOLOGICAL SCIENCES