Trypsin‐Instructed Self‐Assembly on Endoplasmic Reticulum for Selectively Inhibiting Cancer Cells

Enzyme-Instructed Self-Assembly for Cancer Therapy and Imaging

(2020) Beom Jin Kim et al.   BIOCONJUGATE CHEMISTRY

Prognostic  value of dynamic albumin-to-alkaline phosphatase ratio in limited stage small-cell lung cancer

(2019) Xiaogang Li et al.   Future Oncology

The signal peptide plus a cluster of positive charges in prion protein dictate chaperone-mediated Sec61 channel gating

(2019) Anke Ziska et al.   Biology Open

The molecular machinery of regulated cell death

(2019) Daolin Tang et al.   CELL RESEARCH

Furin-mediated intracellular self-assembly of olsalazine nanoparticles for enhanced magnetic resonance imaging and tumour therapy

(2019) Yue Yuan et al.   NATURE MATERIALS

Tandem Molecular Self-Assembly in Liver Cancer Cells

(2018) Jie Zhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzymatic Self-Assembly Confers Exceptionally Strong Synergism with NF-κB Targeting for Selective Necroptosis of Cancer Cells

(2018) Jie Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enzymatic Assemblies Disrupt Membrane and Target Endoplasmic Reticulum (ER) for Selective Cancer Cell Death

(2018) Zhaoqianqi Feng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Endoplasmic Reticulum: Target for Next Generation Cancer Therapy

(2018) Samya Banerjee et al.   CHEMBIOCHEM

Cancer cell nucleus-targeting nanocomposites for advanced tumor therapeutics

(2018) Limin Pan et al.   CHEMICAL SOCIETY REVIEWS

Kinase-controlled phase transition of membraneless organelles in mitosis

(2018) Arpan Kumar Rai et al.   NATURE

Unraveling the Cellular Mechanism of Assembling Cholesterols for Selective Cancer Cell Death

(2018) Huaimin Wang et al.   MOLECULAR CANCER RESEARCH

Enzyme-assisted peptide folding, assembly and anti-cancer properties

(2017) Chunhui Liang et al.   Nanoscale

In situ generated D‐peptidic nanofibrils as multifaceted apoptotic inducers to target cancer cells

(2017) Xuewen Du et al.   Cell Death & Disease

Minimal C-terminal modification boosts peptide self-assembling ability for necroptosis of cancer cells

(2016) Zhaoqianqi Feng et al.   CHEMICAL COMMUNICATIONS

Integrating Enzymatic Self-Assembly and Mitochondria Targeting for Selectively Killing Cancer Cells without Acquired Drug Resistance

(2016) Huaimin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tuning Cellular Uptake of Molecular Probes by Rational Design of Their Assembly into Supramolecular Nanoprobes

(2016) Lye Lin Lock et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enzyme-Instructed Self-Assembly for Spatiotemporal Profiling of the Activities of Alkaline Phosphatases on Live Cells

(2016) Jie Zhou et al.   Chem

Tumor-Specific Formation of Enzyme-Instructed Supramolecular Self-Assemblies as Cancer Theranostics

(2015) Peng Huang et al.   ACS Nano

Intracellular Self-Assembly of Taxol Nanoparticles for Overcoming Multidrug Resistance

(2015) Yue Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeting the lysosome in cancer

(2015) Shengfu Piao et al.   Annals of the New York Academy of Sciences

Enzyme-Instructed Self-Assembly: A Multistep Process for Potential Cancer Therapy

(2015) Jie Zhou et al.   BIOCONJUGATE CHEMISTRY

The endoplasmic reticulum: structure, function and response to cellular signaling

(2015) Dianne S. Schwarz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials

(2015) Xuewen Du et al.   CHEMICAL REVIEWS

Taurine Boosts Cellular Uptake of Small d-Peptides for Enzyme-Instructed Intracellular Molecular Self-Assembly

(2015) Jie Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cancer Cell Death Induced by the Intracellular Self-Assembly of an Enzyme-Responsive Supramolecular Gelator

(2015) Akiko Tanaka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Controlling Cancer Cell Fate Using Localized Biocatalytic Self-Assembly of an Aromatic Carbohydrate Amphiphile

(2015) Ricardo A. Pires et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pharmacogenomic agreement between two cancer cell line data sets

(2015) Nicolas Stransky et al.   NATURE

Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells

(2015) S Saveljeva et al.   Cell Death & Disease

Enzyme-Controlled Intracellular Self-Assembly of 18F Nanoparticles for Enhanced MicroPET Imaging of Tumor

(2015) Yaling Liu et al.   Theranostics

Pericellular Hydrogel/Nanonets Inhibit Cancer Cells

(2014) Yi Kuang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanopreparations for organelle-specific delivery in cancer

(2013) Swati Biswas et al.   ADVANCED DRUG DELIVERY REVIEWS

CHOP is a multifunctional transcription factor in the ER stress response

(2012) H. Nishitoh   JOURNAL OF BIOCHEMISTRY

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Imaging enzyme-triggered self-assembly of small molecules inside live cells

(2012) Yuan Gao et al.   Nature Communications

A practical guide to evaluating colocalization in biological microscopy

(2011) Kenneth W. Dunn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Bortezomib as the First Proteasome Inhibitor Anticancer Drug: Current Status and Future Perspectives

(2011) D. Chen et al.   CURRENT CANCER DRUG TARGETS

Targeting ER stress induced apoptosis and inflammation in cancer

(2010) Tom Verfaillie et al.   CANCER LETTERS

Combating apoptosis and multidrug resistant cancers by targeting lysosomes

(2010) Line Groth-Pedersen et al.   CANCER LETTERS

Towards novel paradigms for cancer therapy

(2010) V Pavet et al.   ONCOGENE

A biocompatible condensation reaction for controlled assembly of nanostructures in living cells

(2009) Gaolin Liang et al.   Nature Chemistry