BAG3 Pro209 mutants associated with myopathy and neuropathy relocate chaperones of the CASA-complex to aggresomes
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
BAG3 Pro209 mutants associated with myopathy and neuropathy relocate chaperones of the CASA-complex to aggresomes
Authors
Keywords
-
Journal
Scientific Reports
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-05-29
DOI
10.1038/s41598-020-65664-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Small heat shock proteins: multifaceted proteins with important implications for life
- (2019) Serena Carra et al. CELL STRESS & CHAPERONES
- HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease
- (2018) Veronick Benoy et al. BRAIN
- HSPB8 and BAG3 cooperate to promote spatial sequestration of ubiquitinated proteins and coordinate the cellular adaptive response to proteasome insufficiency
- (2018) Solenn M. Guilbert et al. FASEB JOURNAL
- Hsp70–Bag3 complex is a hub for proteotoxicity-induced signaling that controls protein aggregation
- (2018) Anatoli B. Meriin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 234th ENMC International Workshop: Chaperone dysfunction in muscle disease, December 8-10th 2017, Naarden, Netherlands
- (2018) Conrad C. Weihl et al. NEUROMUSCULAR DISORDERS
- P209L Mutation in BAG3 Does Not Cause Cardiomyopathy in Mice
- (2018) Xi Fang et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- HDAC6 as a potential therapeutic target for peripheral nerve disorders
- (2018) Robert Prior et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Myopathy associated BAG3 mutations lead to protein aggregation by stalling Hsp70 networks
- (2018) Melanie Meister-Broekema et al. Nature Communications
- Loss-of-function mutations in co-chaperone BAG3 destabilize small HSPs and cause cardiomyopathy
- (2017) Xi Fang et al. JOURNAL OF CLINICAL INVESTIGATION
- BAG3 Is a Modular, Scaffolding Protein that physically Links Heat Shock Protein 70 (Hsp70) to the Small Heat Shock Proteins
- (2017) Jennifer N. Rauch et al. JOURNAL OF MOLECULAR BIOLOGY
- Mutations in BAG3 cause adult-onset Charcot-Marie-Tooth disease
- (2017) Michael Shy et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Multifunctional p62 Effects Underlie Diverse Metabolic Diseases
- (2017) Min Long et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients
- (2017) Wenting Guo et al. Nature Communications
- p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis
- (2017) Hyunjoo Cha-Molstad et al. Nature Communications
- The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases
- (2017) Paola Rusmini et al. Frontiers in Molecular Neuroscience
- Non-canonical Interactions between Heat Shock Cognate Protein 70 (Hsc70) and Bcl2-associated Anthanogene (BAG) Co-Chaperones Are Important for Client Release
- (2016) Jennifer N. Rauch et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- In vivo aspects of protein folding and quality control
- (2016) D. Balchin et al. SCIENCE
- Breaking BAG: The Co-Chaperone BAG3 in Health and Disease
- (2016) Christian Behl TRENDS IN PHARMACOLOGICAL SCIENCES
- Rapid flow cytometric measurement of protein inclusions and nuclear trafficking
- (2016) D. R. Whiten et al. Scientific Reports
- The CamSol Method of Rational Design of Protein Mutants with Enhanced Solubility
- (2015) Pietro Sormanni et al. JOURNAL OF MOLECULAR BIOLOGY
- The Selective Autophagy Receptor p62 Forms a Flexible Filamentous Helical Scaffold
- (2015) Rodolfo Ciuffa et al. Cell Reports
- BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta
- (2014) Melania Minoia et al. Autophagy
- Unusual multisystemic involvement and a novel BAG3 mutation revealed by NGS screening in a large cohort of myofibrillar myopathies
- (2014) Anna-Lena Semmler et al. Orphanet Journal of Rare Diseases
- Co-translational mechanisms of protein maturation
- (2013) Felix Gloge et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- NIH Image to ImageJ: 25 years of image analysis
- (2012) Caroline A Schneider et al. NATURE METHODS
- BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins
- (2011) Martin Gamerdinger et al. EMBO REPORTS
- A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy
- (2011) Eric Villard et al. EUROPEAN HEART JOURNAL
- HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease
- (2011) Constantin d'Ydewalle et al. NATURE MEDICINE
- Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradation
- (2011) K.-i. Fujita et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chaperone-Assisted Selective Autophagy Is Essential for Muscle Maintenance
- (2010) Verena Arndt et al. CURRENT BIOLOGY
- The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS)
- (2010) Valeria Crippa et al. HUMAN MOLECULAR GENETICS
- Identification of the key structural motifs involved in HspB8/HspB6–Bag3 interaction
- (2009) Margit Fuchs et al. BIOCHEMICAL JOURNAL
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More