A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors
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Title
A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors
Authors
Keywords
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Journal
Nature Communications
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-03-27
DOI
10.1038/s41467-020-15418-2
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Note: Only part of the references are listed.- Papain-like cysteine proteases prepare plant cyclic peptide precursors for cyclization
- (2019) Fabian B. H. Rehm et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rapid and Scalable Plant-Based Production of a Potent Plasmin Inhibitor Peptide
- (2019) Mark A. Jackson et al. Frontiers in Plant Science
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- (2019) Karen S. Harris et al. Scientific Reports
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- (2018) Florian B. Zauner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Buried treasure: biosynthesis, structures and applications of cyclic peptides hidden in seed storage albumins
- (2018) B. Franke et al. NATURAL PRODUCT REPORTS
- Designing macrocyclic disulfide-rich peptides for biotechnological applications
- (2018) Conan K. Wang et al. Nature Chemical Biology
- Crystal Structure of Plant Legumain Reveals a Unique Two-Chain State with pH-Dependent Activity Regulation
- (2018) Florian B. Zauner et al. PLANT CELL
- Structural basis of ribosomal peptide macrocyclization in plants
- (2018) Joel Haywood et al. eLife
- One-Pot Dual Labeling of IgG 1 and Preparation of C-to-C Fusion Proteins Through a Combination of Sortase A and Butelase 1
- (2018) Thibault J. Harmand et al. BIOCONJUGATE CHEMISTRY
- Potent, Selective, and Cell-Penetrating Inhibitors of Kallikrein-Related Peptidase 4 Based on the Cyclic Peptide MCoTI-II
- (2018) Joakim E. Swedberg et al. ACS Medicinal Chemistry Letters
- Segmental isotopic labeling of a single-domain globular protein without any refolding step by an asparaginyl endopeptidase
- (2017) Kornelia M. Mikula et al. FEBS LETTERS
- Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta
- (2017) Simon Poon et al. JOURNAL OF EXPERIMENTAL BOTANY
- Engineering a Catalytically Efficient Recombinant Protein Ligase
- (2017) Renliang Yang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Characterization of a dual function macrocyclase enables design and use of efficient macrocyclization substrates
- (2017) Clarissa M. Czekster et al. Nature Communications
- Evaluation of Methods for the Calculation of the pKa of Cysteine Residues in Proteins
- (2016) Ernest Awoonor-Williams et al. Journal of Chemical Theory and Computation
- Total Synthesis of Circular Bacteriocins by Butelase 1
- (2016) Xinya Hemu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Butelase-mediated cyclization and ligation of peptides and proteins
- (2016) Giang K T Nguyen et al. Nature Protocols
- Rationalising pKa shifts in Bacillus circulans xylanase with computational studies
- (2016) Kela Xiao et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy
- (2016) Lai Yue Chan et al. Scientific Reports
- Structure and Mechanism of an Aspartimide-Dependent Peptide Ligase in Human Legumain
- (2015) Elfriede Dall et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Butelase-mediated synthesis of protein thioesters and its application for tandem chemoenzymatic ligation
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- (2015) Kalia Bernath-Levin et al. CHEMISTRY & BIOLOGY
- ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB
- (2015) James A. Maier et al. Journal of Chemical Theory and Computation
- Butelase 1: A Versatile Ligase for Peptide and Protein Macrocyclization
- (2015) Giang K. T. Nguyen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase
- (2015) Karen S. Harris et al. Nature Communications
- Trimmomatic: a flexible trimmer for Illumina sequence data
- (2014) Anthony M. Bolger et al. BIOINFORMATICS
- Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage
- (2014) Lixia Zhao et al. CELL RESEARCH
- Peptide Macrocyclization Catalyzed by a Prolyl Oligopeptidase Involved in α-Amanitin Biosynthesis
- (2014) Hong Luo et al. CHEMISTRY & BIOLOGY
- Backbone cyclization of a recombinant cystine-knot peptide by engineered Sortase A
- (2014) Karen Stanger et al. FEBS LETTERS
- The Evolution ofMomordicaCyclic Peptides
- (2014) Tunjung Mahatmanto et al. MOLECULAR BIOLOGY AND EVOLUTION
- Butelase 1 is an Asx-specific ligase enabling peptide macrocyclization and synthesis
- (2014) Giang K T Nguyen et al. Nature Chemical Biology
- In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide
- (2013) Yanbin Ji et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Mechanistic and structural studies on legumain explain its zymogenicity, distinct activation pathways, and regulation
- (2013) E. Dall et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Insights into Processing and Cyclization Events Associated with Biosynthesis of the Cyclic Peptide Kalata B1
- (2012) Brendon F. Conlan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Novel Cyclotides and Uncyclotides with Highly Shortened Precursors fromChassalia chartaceaand Effects of Methionine Oxidation on Bioactivities
- (2012) Giang Kien Truc Nguyen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
- (2012) Paul G. Arnison et al. NATURAL PRODUCT REPORTS
- Cyclic Peptides Arising by Evolutionary Parallelism via Asparaginyl-Endopeptidase-Mediated Biosynthesis
- (2012) J. S. Mylne et al. PLANT CELL
- Electrostatic Contribution of Surface Charge Residues to the Stability of a Thermophilic Protein: Benchmarking Experimental and Predicted pKa Values
- (2012) Chi-Ho Chan et al. PLoS One
- Host-Defense Activities of Cyclotides
- (2012) David J. Craik Toxins
- Activation of legumain involves proteolytic and conformational events, resulting in a context- and substrate-dependent activity profile
- (2011) Elfriede Dall et al. Acta Crystallographica Section F-Structural Biology and Crystallization Communications
- PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKaPredictions
- (2011) Mats H. M. Olsson et al. Journal of Chemical Theory and Computation
- Full-length transcriptome assembly from RNA-Seq data without a reference genome
- (2011) Manfred G Grabherr et al. NATURE BIOTECHNOLOGY
- Albumins and their processing machinery are hijacked for cyclic peptides in sunflower
- (2011) Joshua S Mylne et al. Nature Chemical Biology
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