Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy

Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration

(2015) L. Y. Chan et al.   BIOSCIENCE REPORTS

Peptide therapeutics: current status and future directions

(2015) Keld Fosgerau et al.   DRUG DISCOVERY TODAY

Therapeutic uses of somatostatin and its analogues: Current view and potential applications

(2015) Uma Rai et al.   PHARMACOLOGY & THERAPEUTICS

Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold

(2015) Yen-Hua Huang et al.   Scientific Reports

Triazine-Based Tool Box for Developing Peptidic PET Imaging Probes: Syntheses, Microfluidic Radiolabeling, and Structure–Activity Evaluation

(2014) Hairong Li et al.   BIOCONJUGATE CHEMISTRY

The Cyclic Cystine Ladder of Theta-Defensins as a Stable, Bifunctional Scaffold: A Proof-of-Concept Study Using the Integrin-Binding RGD Motif.

(2014) Anne C. Conibear et al.   CHEMBIOCHEM

Disulfide-rich macrocyclic peptides as templates in drug design

(2014) Susan E. Northfield et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A HER 1-2 Punch: Dual EGFR Targeting Deals Resistance a Deadly Blow

(2014) D. L. Gibbons et al.   Cancer Discovery

Cyclotides as grafting frameworks for protein engineering and drug design applications

(2013) Aaron G. Poth et al.   BIOPOLYMERS

The many facets of PEDF in drug discovery and disease: a diamond in the rough or split personality disorder?

(2013) Susan E Craword et al.   Expert Opinion on Drug Discovery

Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancer

(2013) Jonathan Welti et al.   JOURNAL OF CLINICAL INVESTIGATION

Joseph Rudinger memorial lecture: Discovery and applications of cyclotides

(2013) David J Craik   JOURNAL OF PEPTIDE SCIENCE

In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

(2013) Yanbin Ji et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

 v Integrins in Angiogenesis and Cancer

(2013) S. M. Weis et al.   Cold Spring Harbor Perspectives in Medicine

Orally Active Peptidic Bradykinin B1 Receptor Antagonists Engineered from a Cyclotide Scaffold for Inflammatory Pain Treatment

(2012) Clarence T. T. Wong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Anti-angiogenesis therapy in cancer: Current challenges and future perspectives

(2012) Farbod Shojaei   CANCER LETTERS

The Future of Peptide-based Drugs

(2012) David J. Craik et al.   Chemical Biology & Drug Design

Modeling and predicting clinical efficacy for drugs targeting the tumor milieu

(2012) Mallika Singh et al.   NATURE BIOTECHNOLOGY

Ophthalmic drug discovery: novel targets and mechanisms for retinal diseases and glaucoma

(2012) Kang Zhang et al.   NATURE REVIEWS DRUG DISCOVERY

Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds

(2011) L. Y. Chan et al.   BLOOD

Improvement of drug-like properties of peptides: the somatostatin paradigm

(2010) Oded Ovadia et al.   Expert Opinion on Drug Discovery

Topical application of anti-angiogenic peptides based on pigment epithelium-derived factor can improve psoriasis

(2010) Riichiro Abe et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Somatostatin Receptor-Targeted Anti-Cancer Therapy

(2010) Li-Chun Sun et al.   Current Drug Delivery

Performance and consistency of care in admitted trauma patients: our next great opportunity in trauma care?

(2009) Wei Chong Chua et al.   ANZ JOURNAL OF SURGERY

Isolation and Characterization of Peptides fromMomordica cochinchinensisSeeds

(2009) Lai Y. Chan et al.   JOURNAL OF NATURAL PRODUCTS

Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors

(2009) Andrew R Reynolds et al.   NATURE MEDICINE

Engineering Stabilized Vascular Endothelial Growth Factor-A Antagonists: Synthesis, Structural Characterization, and Bioactivity of Grafted Analogues of Cyclotides

(2008) Sunithi Gunasekera et al.   JOURNAL OF MEDICINAL CHEMISTRY