Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells

A PLK1 kinase inhibitor enhances the chemosensitivity of cisplatin by inducing pyroptosis in oesophageal squamous cell carcinoma

(2019) Mengjiao Wu et al.   EBioMedicine

Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells

(2019) Junhui Yu et al.   Cell Death & Disease

Chemotherapeutic paclitaxel and cisplatin differentially induce pyroptosis in A549 lung cancer cells via caspase-3/GSDME activation

(2019) Cheng-cheng Zhang et al.   APOPTOSIS

Programmed necrotic cell death of macrophages: Focus on pyroptosis, necroptosis, and parthanatos

(2019) Nirmal Robinson et al.   Redox Biology

GSDME mediates caspase-3-dependent pyroptosis in gastric cancer

(2018) Yubin Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis

(2018) Zhentao Yang et al.   NATURE CELL BIOLOGY

Molecular mechanisms of non-thermal plasma-induced effects in cancer cells

(2018) Hiromasa Tanaka et al.   BIOLOGICAL CHEMISTRY

Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis 

(2018) Bo Zhou et al.   CELL RESEARCH

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

GSDME as an executioner of chemotherapy-induced cell death

(2017) Xiaoliang Yu et al.   Science China-Life Sciences

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

(2017) Jianjin Shi et al.   TRENDS IN BIOCHEMICAL SCIENCES

NLRP3 inflammasome activation mediates radiation-induced pyroptosis in bone marrow-derived macrophages

(2017) Yan-gang Liu et al.   Cell Death & Disease

Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells

(2017) Farhan Basit et al.   Cell Death & Disease

Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death

(2017) Corey Rogers et al.   Nature Communications

Chemically different non-thermal plasmas target distinct cell death pathways

(2017) Oleg Lunov et al.   Scientific Reports

Pore-forming activity and structural autoinhibition of the gasdermin family

(2016) Jingjin Ding et al.   NATURE

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

(2016) Xing Liu et al.   NATURE

Non-thermal gas plasma-induced endoplasmic reticulum stress mediates apoptosis in human colon cancer cells

(2016) Madduma Hewage Susara Ruwan Kumara et al.   ONCOLOGY REPORTS

Reactive species in non-equilibrium atmospheric-pressure plasmas: Generation, transport, and biological effects

(2016) X. Lu et al.   PHYSICS REPORTS-REVIEW SECTION OF PHYSICS LETTERS

Contribution of hydrogen peroxide to non-thermal atmospheric pressure plasma induced A549 lung cancer cell damage

(2016) Jie Ma et al.   Plasma Processes and Polymers

Toward understanding the selective anticancer capacity of cold atmospheric plasma—A model based on aquaporins (Review)

(2015) Dayun Yan et al.   Biointerphases

Non-thermal plasma treatment altered gene expression profiling in non-small-cell lung cancer A549 cells

(2015) Jue Hou et al.   BMC GENOMICS

Plasma-activated medium induces A549 cell injury via a spiral apoptotic cascade involving the mitochondrial–nuclear network

(2015) Tetsuo Adachi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

The deafness gene DFNA5 induces programmed cell death through mitochondria and MAPK-related pathways

(2015) Sofie Van Rossom et al.   Frontiers in Cellular Neuroscience

Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells: an in vitro and in vivo study

(2015) H-Y Li et al.   Cell Death & Disease

Toward understanding the selective anticancer capacity of cold atmospheric plasma—A model based on aquaporins (Review)

(2015) Dayun Yan et al.   Biointerphases

DFNA5, a Gene Involved in Hearing Loss and Cancer: A Review

(2014) Ken Op de Beeck et al.   ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY

The splicing mutant of the human tumor suppressor protein DFNA5 induces programmed cell death when expressed in the yeast Saccharomyces cerevisiae

(2012) Sofie Van Rossom et al.   Frontiers in Oncology

The DFNA5 gene, responsible for hearing loss and involved in cancer, encodes a novel apoptosis-inducing protein

(2011) Ken Op de Beeck et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

ROS implication in a new antitumor strategy based on non-thermal plasma

(2011) Marc Vandamme et al.   INTERNATIONAL JOURNAL OF CANCER

RETRACTED ARTICLE: Non-thermal Plasma Induces Apoptosis in Melanoma Cells via Production of Intracellular Reactive Oxygen Species

(2010) Rachel Sensenig et al.   ANNALS OF BIOMEDICAL ENGINEERING

Mitochondrial control of caspase-dependent and -independent cell death

(2010) Ludivine A. Pradelli et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Induction of cell growth arrest by atmospheric non-thermal plasma in colorectal cancer cells

(2010) Chul-Ho Kim et al.   JOURNAL OF BIOTECHNOLOGY

Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer

(2009) Tomoko Fujikane et al.   BREAST CANCER RESEARCH AND TREATMENT

Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma

(2008) M S Kim et al.   ONCOGENE