DFNA5, a Gene Involved in Hearing Loss and Cancer: A Review

The DFNA5 gene, responsible for hearing loss and involved in cancer, encodes a novel apoptosis-inducing protein

(2011) Ken Op de Beeck et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Genomic Duplication and Overexpression of TJP2/ZO-2 Leads to Altered Expression of Apoptosis Genes in Progressive Nonsyndromic Hearing Loss DFNA51

(2010) Tom Walsh et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Functional Null Mutations of MSRB3 Encoding Methionine Sulfoxide Reductase Are Associated with Human Deafness DFNB74

(2010) Zubair M. Ahmed et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer

(2009) Tomoko Fujikane et al.   BREAST CANCER RESEARCH AND TREATMENT

Five novel loci for inherited hearing loss mapped by SNP-based homozygosity profiles in Palestinian families

(2009) Hashem Shahin et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Activation of cell death pathways in the inner ear of the aging CBA/J mouse

(2009) Su-Hua Sha et al.   HEARING RESEARCH

Evidence for a founder mutation causing DFNA5 hearing loss in East Asians

(2009) Hong-Joon Park et al.   JOURNAL OF HUMAN GENETICS

Methylation of the DFNA5 increases risk of lymph node metastasis in human breast cancer

(2008) Myoung Sook Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Characterization of the murine Dfna5 promoter and regulatory regions

(2008) Karen Vrijens et al.   GENE

Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma

(2008) M S Kim et al.   ONCOGENE