Metformin Promotes Beclin1-Dependent Autophagy to Inhibit the Progression of Gastric Cancer

A Cohort Study of Antihyperglycemic Medication Exposure and Gastric Cancer Risk

(2020) Audrius Dulskas et al.   Journal of Clinical Medicine

Metformin Counteracts HCC Progression and Metastasis Enhancing KLF6/p21 Expression and Downregulating the IGF Axis

(2019) Fernanda Vacante et al.   International Journal of Endocrinology

Autophagy dysfunctions associated with cancer cells and their therapeutic implications

(2019) Aurelian Udristioiu et al.   BIOMEDICINE & PHARMACOTHERAPY

Glycochenodeoxycholate promotes hepatocellular carcinoma invasion and migration by AMPK/mTOR dependent autophagy activation

(2019) Lu Gao et al.   CANCER LETTERS

Metformin inhibits progression of Head and Neck Squamous Cell Carcinoma by acting Directly on Carcinoma Initiating Cells

(2019) Xingyu Wu et al.   CANCER RESEARCH

Metformin targets a YAP1-TEAD4 complex via AMPKα to regulate CCNE1/2 in bladder cancer cells

(2019) Yanju Wu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Metformin suppresses the esophageal carcinogenesis in rats treated with NMBzA through inhibiting AMPK/mTOR signaling pathway

(2018) Hongjun Fan et al.   CARCINOGENESIS

Metformin suppresses cancer initiation and progression in genetic mouse models of pancreatic cancer

(2017) Ke Chen et al.   Molecular Cancer

Metformin reduces gastric cancer risk in patients with type 2 diabetes mellitus

(2016) Chin-Hsiao Tseng   Aging-US

AMPK regulates autophagy by phosphorylating BECN1 at threonine 388

(2016) Deyi Zhang et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Metformin Activates AMPK through the Lysosomal Pathway

(2016) Chen-Song Zhang et al.   Cell Metabolism

Metformin reduces glycometabolism of papillary thyroid carcinomain vitroandin vivo

(2016) Chen-Tian Shen et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Metformin: An anti-diabetic drug to fight cancer

(2016) Marie Daugan et al.   PHARMACOLOGICAL RESEARCH

5-Aminoimidazole-4-carboxamide-1-β-4-ribofuranoside (AICAR) enhances the efficacy of rapamycin in human cancer cells

(2015) Suman Mukhopadhyay et al.   CELL CYCLE

Reciprocal Regulation of AMP-activated Protein Kinase and Phospholipase D

(2015) Suman Mukhopadhyay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR: a pharmacologic target for autophagy regulation

(2015) Young Chul Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway

(2015) Xiaodi Fan et al.   Journal of Translational Medicine

Management of Hyperglycemia in Type 2 Diabetes, 2015: A Patient-Centered Approach: Update to a Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes

(2014) Silvio E. Inzucchi et al.   DIABETES CARE

The machinery of macroautophagy

(2013) Yuchen Feng et al.   CELL RESEARCH

Autophagy modulation for cancer therapy

(2011) Zhineng J. Yang et al.   CANCER BIOLOGY & THERAPY

The Beclin 1 network regulates autophagy and apoptosis

(2011) R Kang et al.   CELL DEATH AND DIFFERENTIATION

Principles and Current Strategies for Targeting Autophagy for Cancer Treatment

(2011) R. K. Amaravadi et al.   CLINICAL CANCER RESEARCH

The Role of Autophagy in Cancer: Therapeutic Implications

(2011) Z. J. Yang et al.   MOLECULAR CANCER THERAPEUTICS

The autophagy effector Beclin 1: a novel BH3-only protein

(2009) S Sinha et al.   ONCOGENE

An Atg4B Mutant Hampers the Lipidation of LC3 Paralogues and Causes Defects in Autophagosome Closure

(2008) Naonobu Fujita et al.   MOLECULAR BIOLOGY OF THE CELL