Metformin reduces glycometabolism of papillary thyroid carcinomain vitroandin vivo

Cancer statistics in China, 2015

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Cancer statistics, 2016

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No evidence for a decreased risk of thyroid cancer in association with use of metformin or other antidiabetic drugs: a case-control study

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Prognostic Value of 18F-FDG PET/CT Metabolic Parameters in Metastatic Differentiated Thyroid Cancers

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IMAGING IN ENDOCRINOLOGY: 18F-FDG PET/CT in differentiated thyroid carcinoma: clinical indications and controversies in the diagnosis and follow- up of differentiated thyroid cancer

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Metformin: A Novel Biological Modifier of Tumor Response to Radiation Therapy

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Metformin: A Novel but Controversial Drug in Cancer Prevention and Treatment

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Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy

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Metformin and Cancer Risk and Mortality: A Systematic Review and Meta-analysis Taking into Account Biases and Confounders

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Therapeutic potential of metformin in papillary thyroid cancer in vitro and in vivo

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Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase

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Metformin Reduces Thyroid Cancer Risk in Taiwanese Patients with Type 2 Diabetes

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Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis

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Direct inhibition of hexokinase activity by metformin at least partially impairs glucose metabolism and tumor growth in experimental breast cancer

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Treatment With Metformin Is Associated With Higher Remission Rate in Diabetic Patients With Thyroid Cancer

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Metformin--an Adjunct Antineoplastic Therapy--Divergently Modulates Tumor Metabolism and Proliferation, Interfering with Early Response Prediction by 18F-FDG PET Imaging

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Metformin Impairs Glucose Consumption and Survival in Calu-1 Cells by Direct Inhibition of Hexokinase-II

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AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo

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Metformin Inhibits Growth of Thyroid Carcinoma Cells, Suppresses Self-Renewal of Derived Cancer Stem Cells, and Potentiates the Effect of Chemotherapeutic Agents

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Investigating Metformin for Cancer Prevention and Treatment: The End of the Beginning

(2012) Michael N. Pollak   Cancer Discovery

Metformin and cancer: new applications for an old drug

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Targeting cancer metabolism: a therapeutic window opens

(2011) Matthew G. Vander Heiden   NATURE REVIEWS DRUG DISCOVERY

Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation

(2010) Simon A. Hawley et al.   Cell Metabolism

Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase

(2010) Carolyn Algire et al.   ENDOCRINE-RELATED CANCER

AMPK in Health and Disease

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Is Akt the “Warburg kinase”?—Akt-energy metabolism interactions and oncogenesis

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The prevention of type 2 diabetes

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