Mechanistic Differences in Cell Death Responses to Metal‐Based Engineered Nanomaterials in Kupffer Cells and Hepatocytes

The Crystallinity and Aspect Ratio of Cellulose Nanomaterials Determine Their Pro‐Inflammatory and Immune Adjuvant Effects In Vitro and In Vivo

(2019) Xiang Wang et al.   Small

Toxicological Profiling of Metal Oxide Nanoparticles in Liver Context Reveals Pyroptosis in Kupffer Cells and Macrophages versus Apoptosis in Hepatocytes

(2018) Vahid Mirshafiee et al.   ACS Nano

Epigallocatechin-3-gallate protected vanadium-induced eggshell depigmentation via P38MAPK-Nrf2/HO-1 signaling pathway in laying hens

(2018) J Wang et al.   POULTRY SCIENCE

Toxicological Profiling of Highly Purified Single-Walled Carbon Nanotubes with Different Lengths in the Rodent Lung and Escherichia Coli

(2018) Xiang Wang et al.   Small

Critical review of the safety assessment of titanium dioxide additives in food

(2018) Hans Christian Winkler et al.   JOURNAL OF NANOBIOTECHNOLOGY

Inhibition of Kupffer Cell Autophagy Abrogates Nanoparticle-Induced Liver Injury

(2017) Shasha Zhu et al.   Advanced Healthcare Materials

Repetitive Dosing of Fumed Silica Leads to Profibrogenic Effects through Unique Structure–Activity Relationships and Biopersistence in the Lung

(2016) Bingbing Sun et al.   ACS Nano

Toxicological Profiling of Highly Purified Metallic and Semiconducting Single-Walled Carbon Nanotubes in the Rodent Lung and E. coli

(2016) Xiang Wang et al.   ACS Nano

The safety of nanostructured synthetic amorphous silica (SAS) as a food additive (E 551)

(2016) Claudia Fruijtier-Pölloth   ARCHIVES OF TOXICOLOGY

Pyroptosis

(2016) Lieselotte Vande Walle et al.   CURRENT BIOLOGY

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

(2016) Xing Liu et al.   NATURE

GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes

(2016) Robin A. Aglietti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of the Vanadate-Inhibited Ca 2+ -ATPase

(2016) Johannes D. Clausen et al.   STRUCTURE

Reduction of Acute Inflammatory Effects of Fumed Silica Nanoparticles in the Lung by Adjusting Silanol Display through Calcination and Metal Doping

(2015) Bingbing Sun et al.   ACS Nano

Use of a Pro-Fibrogenic Mechanism-Based Predictive Toxicological Approach for Tiered Testing and Decision Analysis of Carbonaceous Nanomaterials

(2015) Xiang Wang et al.   ACS Nano

Enhancing the Imaging and Biosafety of Upconversion Nanoparticles through Phosphonate Coating

(2015) Ruibin Li et al.   ACS Nano

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

Structural and functional hepatocyte polarity and liver disease

(2015) Paul Gissen et al.   JOURNAL OF HEPATOLOGY

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

NADPH Oxidase-Dependent NLRP3 Inflammasome Activation and its Important Role in Lung Fibrosis by Multiwalled Carbon Nanotubes

(2015) Bingbing Sun et al.   Small

Interference in Autophagosome Fusion by Rare Earth Nanoparticles Disrupts Autophagic Flux and Regulation of an Interleukin-1β Producing Inflammasome

(2014) Ruibin Li et al.   ACS Nano

Aspect Ratio Plays a Role in the Hazard Potential of CeO2 Nanoparticles in Mouse Lung and Zebrafish Gastrointestinal Tract

(2014) Sijie Lin et al.   ACS Nano

Rapid and Sensitive Assessment of Human Hepatocyte Functions

(2014) Roberto Gramignoli et al.   CELL TRANSPLANTATION

PdO Doping Tunes Band-Gap Energy Levels as Well as Oxidative Stress Responses to a Co3O4 p-Type Semiconductor in Cells and the Lung

(2014) Haiyuan Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hepatic toxicology following single and multiple exposure of engineered nanomaterials utilising a novel primary human 3D liver microtissue model

(2014) Ali Kermanizadeh et al.   Particle and Fibre Toxicology

Purinergic signaling via P2X7 receptor mediates IL-1β production in Kupffer cells exposed to silica nanoparticle

(2014) Shuji Kojima et al.   TOXICOLOGY

Dysregulation of Macrophage Activation Profiles by Engineered Nanoparticles

(2013) Vamsi Kodali et al.   ACS Nano

Surface Charge and Cellular Processing of Covalently Functionalized Multiwall Carbon Nanotubes Determine Pulmonary Toxicity

(2013) Ruibin Li et al.   ACS Nano

Engineering an Effective Immune Adjuvant by Designed Control of Shape and Crystallinity of Aluminum Oxyhydroxide Nanoparticles

(2013) Bingbing Sun et al.   ACS Nano

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

(2013) Patricio Godoy et al.   ARCHIVES OF TOXICOLOGY

Toxicological effect of engineered nanomaterials on the liver

(2013) A Kermanizadeh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Interlaboratory Evaluation of in Vitro Cytotoxicity and Inflammatory Responses to Engineered Nanomaterials: The NIEHS Nano GO Consortium

(2013) Tian Xia et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Subversion of inflammasome activation and pyroptosis by pathogenic bacteria

(2013) Larissa D. Cunha et al.   Frontiers in Cellular and Infection Microbiology

Use of Metal Oxide Nanoparticle Band Gap To Develop a Predictive Paradigm for Oxidative Stress and Acute Pulmonary Inflammation

(2012) Haiyuan Zhang et al.   ACS Nano

Designed Synthesis of CeO2 Nanorods and Nanowires for Studying Toxicological Effects of High Aspect Ratio Nanomaterials

(2012) Zhaoxia Ji et al.   ACS Nano

Processing Pathway Dependence of Amorphous Silica Nanoparticle Toxicity: Colloidal vs Pyrolytic

(2012) Haiyuan Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pluronic F108 Coating Decreases the Lung Fibrosis Potential of Multiwall Carbon Nanotubes by Reducing Lysosomal Injury

(2012) Xiang Wang et al.   NANO LETTERS

An in vitro liver model - assessing oxidative stress and genotoxicity following exposure of hepatocytes to a panel of engineered nanomaterials

(2012) Ali Kermanizadeh et al.   Particle and Fibre Toxicology

NLRP3 Inflammasome Activation Induced by Engineered Nanomaterials

(2012) Bingbing Sun et al.   Small

Hepatocytes produce tumor necrosis factor-α and interleukin-6 in response to Porphyromonas gingivalis

(2011) M. Takano et al.   JOURNAL OF PERIODONTAL RESEARCH

Role of Fe Doping in Tuning the Band Gap of TiO2for the Photo-Oxidation-Induced Cytotoxicity Paradigm

(2011) Saji George et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY