Next‐Generation Sequencing Reveals Differential Responses to Acute versus Long‐Term Exposures to Graphene Oxide in Human Lung Cells

Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins

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Using Large Datasets to Understand Nanotechnology

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Multiwall Carbon Nanotubes Induce More Pronounced Transcriptomic Responses in Pseudomonas aeruginosa PG201 than Graphene, Exfoliated Boron Nitride, or Carbon Black

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Graphene and graphene oxide induce ROS production in human HaCaT skin keratinocytes: the role of xanthine oxidase and NADH dehydrogenase

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Advanced tools for the safety assessment of nanomaterials

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RNA-sequencing reveals long-term effects of silver nanoparticles on human lung cells

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A blueprint for the synthesis and characterisation of thin graphene oxide with controlled lateral dimensions for biomedicine

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Immunological impact of graphene oxide sheets in the abdominal cavity is governed by surface reactivity

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Safety Assessment of Graphene-Based Materials: Focus on Human Health and the Environment

(2018) Bengt Fadeel et al.   ACS Nano

Molecular Mechanisms of Developmental Toxicity Induced by Graphene Oxide at Predicted Environmental Concentrations

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Comparative in vitro study of single and four layer graphene oxide nanoflakes — Cytotoxicity and cellular uptake

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Cytokine Profiling of Primary Human Macrophages Exposed to Endotoxin-Free Graphene Oxide: Size-Independent NLRP3 Inflammasome Activation

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Differential cytotoxic effects of graphene and graphene oxide on skin keratinocytes

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Cerium oxide nanoparticles inhibit differentiation of neural stem cells

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Cells Respond to Distinct Nanoparticle Properties with Multiple Strategies As Revealed by Single-Cell RNA-Seq

(2016) Hugh D. Mitchell et al.   ACS Nano

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(2016) Chigusa Nakahashi-Oda et al.   NATURE IMMUNOLOGY

Detection of Endotoxin Contamination of Graphene Based Materials Using the TNF-α Expression Test and Guidelines for Endotoxin-Free Graphene Oxide Production

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Emerging systems biology approaches in nanotoxicology: Towards a mechanism-based understanding of nanomaterial hazard and risk

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Long-term exposures to low doses of silver nanoparticles enhanced in vitro malignant cell transformation in non-tumorigenic BEAS-2B cells

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Physico-chemical properties based differential toxicity of graphene oxide/reduced graphene oxide in human lung cells mediated through oxidative stress

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Crucial Role of Lateral Size for Graphene Oxide in Activating Macrophages and Stimulating Pro-inflammatory Responses in Cells and Animals

(2015) Juan Ma et al.   ACS Nano

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

Orchestrating high-throughput genomic analysis with Bioconductor

(2015) Wolfgang Huber et al.   NATURE METHODS

Multi-walled carbon nanotubes directly induce epithelial-mesenchymal transition in human bronchial epithelial cells via the TGF-β-mediated Akt/GSK-3β/SNAIL-1 signalling pathway

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Next-Generation Sequencing Reveals Low-Dose Effects of Cationic Dendrimers in Primary Human Bronchial Epithelial Cells

(2014) Neus Feliu et al.   ACS Nano

Long-term exposures to low doses of titanium dioxide nanoparticles induce cell transformation, but not genotoxic damage in BEAS-2B cells

(2014) Gerard Vales et al.   Nanotoxicology

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

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Causal analysis approaches in Ingenuity Pathway Analysis

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A systems toxicology approach to the surface functionality control of graphene–cell interactions

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Programmed Cell Death: Molecular Mechanisms and Implications for Safety Assessment of Nanomaterials

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Solution-Engineered Palladium Nanoparticles: Model for Health Effect Studies of Automotive Particulate Pollution

(2011) Kai E. Wilkinson et al.   ACS Nano

The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways

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Carbon Nanotubes Induce Malignant Transformation and Tumorigenesis of Human Lung Epithelial Cells

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Apoptotic Cells Activate the "Phoenix Rising" Pathway to Promote Wound Healing and Tissue Regeneration

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Nα-Tosyl-l-phenylalanine Chloromethyl Ketone Induces Caspase-dependent Apoptosis in Transformed Human B Cell Lines with Transcriptional Down-regulation of Anti-apoptotic HS1-associated Protein X-1

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Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

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RNA-Seq: a revolutionary tool for transcriptomics

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