RNA-sequencing reveals long-term effects of silver nanoparticles on human lung cells

Transcriptional profiling reveals gene expression changes associated with inflammation and cell proliferation following short-term inhalation exposure to copper oxide nanoparticles

(2017) Pedro M. Costa et al.   JOURNAL OF APPLIED TOXICOLOGY

DNA methylation changes in human lung epithelia cells exposed to multi-walled carbon nanotubes

(2017) Marta I. Sierra et al.   Nanotoxicology

Acute toxicity and genotoxicity of silver nanoparticle in rats

(2017) Hairuo Wen et al.   PLoS One

Cerium oxide nanoparticles inhibit differentiation of neural stem cells

(2017) Anda R. Gliga et al.   Scientific Reports

Transforming Growth Factor-β: Master Regulator of the Respiratory System in Health and Disease

(2016) Yael Aschner et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Genotoxic and cell-transformation effects of multi-walled carbon nanotubes (MWCNT) following in vitro sub-chronic exposures

(2016) Gerard Vales et al.   JOURNAL OF HAZARDOUS MATERIALS

Genotoxicity of TiO2nanoparticles assessed by mini-gel comet assay and micronucleus scoring with flow cytometry

(2016) Sebastiano Di Bucchianico et al.   MUTAGENESIS

Frozen dispersions of nanomaterials are a useful operational procedure in nanotoxicology

(2016) Laura Vila et al.   Nanotoxicology

Size- and coating-dependent cytotoxicity and genotoxicity of silver nanoparticles evaluated usingin vitrostandard assays

(2016) Xiaoqing Guo et al.   Nanotoxicology

Aerosolized Silver Nanoparticles in the Rat Lung and Pulmonary Responses over Time

(2016) Rona M. Silva et al.   TOXICOLOGIC PATHOLOGY

Death and cell cycle progression are differently conditioned by the AgNP size in osteoblast-like cells

(2016) F. Rosário et al.   TOXICOLOGY

Emerging systems biology approaches in nanotoxicology: Towards a mechanism-based understanding of nanomaterial hazard and risk

(2016) Pedro M. Costa et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Long-term exposures to low doses of silver nanoparticles enhanced in vitro malignant cell transformation in non-tumorigenic BEAS-2B cells

(2016) Wun Hak Choo et al.   TOXICOLOGY IN VITRO

Use of Synchrotron Radiation-Analytical Techniques To Reveal Chemical Origin of Silver-Nanoparticle Cytotoxicity

(2015) Liming Wang et al.   ACS Nano

Platelet-Derived Growth Factor and Transforming Growth Factor β1 Regulate ARDS-Associated Lung Fibrosis Through Distinct Signaling Pathways

(2015) Xingqi Deng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Human bronchial epithelial BEAS-2B cells, an appropriate in vitro model to study heavy metals induced carcinogenesis

(2015) Youn-hee Park et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

HIF-1α Promotes Epithelial-Mesenchymal Transition and Metastasis through Direct Regulation of ZEB1 in Colorectal Cancer

(2015) Wenjing Zhang et al.   PLoS One

Next-Generation Sequencing Reveals Low-Dose Effects of Cationic Dendrimers in Primary Human Bronchial Epithelial Cells

(2014) Neus Feliu et al.   ACS Nano

Less Is More: Long-Term in Vitro Exposure to Low Levels of Silver Nanoparticles Provides New Insights for Nanomaterial Evaluation

(2014) Kristen K. Comfort et al.   ACS Nano

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

A Noncanonical Frizzled2 Pathway Regulates Epithelial-Mesenchymal Transition and Metastasis

(2014) Taranjit S. Gujral et al.   CELL

The extracellular matrix modulates the hallmarks of cancer

(2014) M. W. Pickup et al.   EMBO REPORTS

Long-term exposures to low doses of cobalt nanoparticles induce cell transformation enhanced by oxidative damage

(2014) Balasubramanyam Annangi et al.   Nanotoxicology

Long-term exposures to low doses of titanium dioxide nanoparticles induce cell transformation, but not genotoxic damage in BEAS-2B cells

(2014) Gerard Vales et al.   Nanotoxicology

Comprehensive analysis of DNA methylation data with RnBeads

(2014) Yassen Assenov et al.   NATURE METHODS

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Remodelling the extracellular matrix in development and disease

(2014) Caroline Bonnans et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Low-solubility particles and a Trojan-horse type mechanism of toxicity: the case of cobalt oxide on human lung cells

(2014) Richard Ortega et al.   Particle and Fibre Toxicology

Size-dependent cytotoxicity of silver nanoparticles in human lung cells: the role of cellular uptake, agglomeration and Ag release

(2014) Anda R Gliga et al.   Particle and Fibre Toxicology

Lab-on-a-Chip-Based High-Throughput Screening of the Genotoxicity of Engineered Nanomaterials

(2014) Giuseppe Vecchio et al.   Small

Epithelial–mesenchymal transition involved in pulmonary fibrosis induced by multi-walled carbon nanotubes via TGF-beta/Smad signaling pathway

(2014) Tian Chen et al.   TOXICOLOGY LETTERS

A data-driven approach to preprocessing Illumina 450K methylation array data

(2013) Ruth Pidsley et al.   BMC GENOMICS

Cytotoxicity and genotoxicity assessment of silver nanoparticles in mouse

(2013) Yan Li et al.   Nanotoxicology

Low-level processing of Illumina Infinium DNA Methylation BeadArrays

(2013) Timothy J. Triche et al.   NUCLEIC ACIDS RESEARCH

Use of Coated Silver Nanoparticles to Understand the Relationship of Particle Dissolution and Bioavailability to Cell and Lung Toxicological Potential

(2013) Xiang Wang et al.   Small

Multi-platform genotoxicity analysis of silver nanoparticles in the model cell line CHO-K1

(2013) Xiumei Jiang et al.   TOXICOLOGY LETTERS

Lessons learned from implementing a national infrastructure in Sweden for storage and analysis of next-generation sequencing data

(2013) Samuel Lampa et al.   GigaScience

Genotoxicity of polyvinylpyrrolidone-coated silver nanoparticles in BEAS 2B cells

(2012) Penny Nymark et al.   TOXICOLOGY

Epigenetic effects of nano-sized materials

(2012) Andrea Stoccoro et al.   TOXICOLOGY

Silver Nanoparticles and Total Aerosols Emitted by Nanotechnology-Related Consumer Spray Products

(2011) Marina E. Quadros et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Inhibition of placental growth factor activity reduces the severity of fibrosis, inflammation, and portal hypertension in cirrhotic mice

(2011) Christophe Van Steenkiste et al.   HEPATOLOGY

Exposure assessment of workplaces manufacturing nanosized TiO2and silver

(2011) Ji Hyun Lee et al.   INHALATION TOXICOLOGY

Overcoming anoikis - pathways to anchorage-independent growth in cancer

(2011) M. C. Guadamillas et al.   JOURNAL OF CELL SCIENCE

Carbon Nanotubes Induce Malignant Transformation and Tumorigenesis of Human Lung Epithelial Cells

(2011) Liying Wang et al.   NANO LETTERS

Acute inhalation toxicity of silver nanoparticles

(2010) Jae Hyuck Sung et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS

Subchronic Inhalation Toxicity of Silver Nanoparticles

(2008) Jae Hyuck Sung et al.   TOXICOLOGICAL SCIENCES