Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI

Prevention of rhabdomyolysis-induced acute kidney injury - A DASAIM/DSIT clinical practice guideline

(2019) Jens Michelsen et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Nrf2/ARE Pathway as a Therapeutic Target for the Treatment of Parkinson Diseases

(2019) Artem P. Gureev et al.   NEUROCHEMICAL RESEARCH

Podocyte GSK3 is an evolutionarily conserved critical regulator of kidney function

(2019) J. A. Hurcombe et al.   Nature Communications

MicroRNA-214 promotes chronic kidney disease by disrupting mitochondrial oxidative phosphorylation

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Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury

(2019) Hiroshi Maekawa et al.   Cell Reports

Activation of nuclear receptor PXR impairs glucose tolerance and dysregulates GLUT2 expression and subcellular localization in liver

(2018) Fatemeh Hassani-Nezhad-Gashti et al.   BIOCHEMICAL PHARMACOLOGY

FGFR1-ERK1/2-SOX2 axis promotes cell proliferation, epithelial–mesenchymal transition, and metastasis in FGFR1-amplified lung cancer

(2018) Kaixuan Wang et al.   ONCOGENE

Celastrol ameliorates cisplatin nephrotoxicity by inhibiting NF-κB and improving mitochondrial function

(2018) Xiaowen Yu et al.   EBioMedicine

Cisplatin nephrotoxicity: a review of the literature

(2017) Sandhya Manohar et al.   JOURNAL OF NEPHROLOGY

MicroRNA-709 Mediates Acute Tubular Injury through Effects on Mitochondrial Function

(2017) Yan Guo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

An overview of renal metabolomics

(2017) Sahir Kalim et al.   KIDNEY INTERNATIONAL

Mitochondrial energetics in the kidney

(2017) Pallavi Bhargava et al.   Nature Reviews Nephrology

Mitochondria as therapeutic targets in acute kidney injury

(2016) Andrew M. Hall et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Mitochondrial biogenesis and clearance: a balancing act

(2016) Christina Ploumi et al.   FEBS Journal

Impaired Nrf2 regulation of mitochondrial biogenesis in rostral ventrolateral medulla on hypertension induced by systemic inflammation

(2016) Kay L.H. Wu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Exercise Inducible Lactate Dehydrogenase B Regulates Mitochondrial Function in Skeletal Muscle

(2016) Xijun Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial NADP + -Dependent Isocitrate Dehydrogenase Deficiency Exacerbates Mitochondrial and Cell Damage after Kidney Ischemia-Reperfusion Injury

(2016) Sang Jun Han et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mitochondrial dysfunction in inherited renal disease and acute kidney injury

(2016) Francesco Emma et al.   Nature Reviews Nephrology

Inhibition of lncRNA MIR31HG Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells

(2016) Chanyuan Jin et al.   STEM CELLS

Untargeted plasma and tissue metabolomics in rats with chronic kidney disease given AST-120

(2016) Thomas J. Velenosi et al.   Scientific Reports

Impact of Phosphatidylethanolamine on the Antioxidant Activity of α-Tocopherol and Trolox in Bulk Oil

(2015) Leqi Cui et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Farnesoid X Receptor Protects against Kidney Injury in Uninephrectomized Obese Mice

(2015) Zhibo Gai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysis

(2015) Hiroshi Tsugawa et al.   NATURE METHODS

Mitochondria: a therapeutic target in acute kidney injury

(2015) Yu Ishimoto et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Long-term prognosis after acute kidney injury (AKI): what is the role of baseline kidney function and recovery? A systematic review

(2015) S. Sawhney et al.   BMJ Open

Mitochondrial dynamics and mitochondrial quality control

(2015) Hong-Min Ni et al.   Redox Biology

Decreased nuclear receptor activity and epigenetic modulation associates with down-regulation of hepatic drug-metabolizing enzymes in chronic kidney disease

(2014) Thomas J. Velenosi et al.   FASEB JOURNAL

Acute kidney injury—epidemiology, outcomes and economics

(2014) Oleksa Rewa et al.   Nature Reviews Nephrology

PXR Ablation Alleviates Diet-Induced and Genetic Obesity and Insulin Resistance in Mice

(2013) J. He et al.   DIABETES

From gut to kidney: Transporting and metabolizing calcineurin-inhibitors in solid organ transplantation

(2013) Noël Knops et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Depressed Levels of Prostaglandin F2  in Mice Lacking Akr1b7 Increase Basal Adiposity and Predispose to Diet-Induced Obesity

(2012) F. E. Volat et al.   DIABETES

Nuclear receptors in renal disease

(2011) Moshe Levi   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Estimated Glomerular Filtration Rate Is a Poor Predictor of Concentration for a Broad Range of Uremic Toxins

(2011) S. Eloot et al.   Clinical Journal of the American Society of Nephrology

A simple protocol for amino acid type selective isotope labeling in insect cells with improved yields and high reproducibility

(2011) Alvar D. Gossert et al.   JOURNAL OF BIOMOLECULAR NMR

Aldo-keto reductase 1B7 is a target gene of FXR and regulates lipid and glucose homeostasis

(2011) Xuemei Ge et al.   JOURNAL OF LIPID RESEARCH

Deficiency of PXR decreases atherosclerosis in apoE-deficient mice

(2011) Yipeng Sui et al.   JOURNAL OF LIPID RESEARCH

Drug dosing consideration in patients with acute and chronic kidney disease—a clinical update from Kidney Disease: Improving Global Outcomes (KDIGO)

(2011) Gary R. Matzke et al.   KIDNEY INTERNATIONAL

Reduction of Renal Superoxide Dismutase in Progressive Diabetic Nephropathy

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The Aldo-Keto Reductase Akr1b7 Gene Is a Common Transcriptional Target of Xenobiotic Receptors Pregnane X Receptor and Constitutive Androstane Receptor

(2009) M.-J. Liu et al.   MOLECULAR PHARMACOLOGY

A Multiplexed Quantitative Strategy for Membrane Proteomics

(2008) Chia-Li Han et al.   MOLECULAR & CELLULAR PROTEOMICS