Farnesoid X Receptor Protects against Kidney Injury in Uninephrectomized Obese Mice

Uninephrectomy augments the effects of high fat diet induced obesity on gene expression in mouse kidney

(2014) Zhibo Gai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Derivative of Bardoxolone Methyl, dh404, in an Inverse Dose-Dependent Manner Lessens Diabetes-Associated Atherosclerosis and Improves Diabetic Kidney Disease

(2014) S. M. Tan et al.   DIABETES

Tauroursodeoxycholic Acid Attenuates Progression of Steatohepatitis in Mice Fed a Methionine–Choline-Deficient Diet

(2014) Eun-Ju Cho et al.   DIGESTIVE DISEASES AND SCIENCES

Effect of Redox Modulating NRF2 Activators on Chronic Kidney Disease

(2014) Bo-hyun Choi et al.   MOLECULES

Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development

(2014) Hyun Mi Kang et al.   NATURE MEDICINE

Genome-Wide Binding and Transcriptome Analysis of Human Farnesoid X Receptor in Primary Human Hepatocytes

(2014) Le Zhan et al.   PLoS One

Fatty kidney: emerging role of ectopic lipid in obesity-related renal disease

(2014) Aiko P J de Vries et al.   Lancet Diabetes & Endocrinology

AMPK dysregulation promotes diabetes-related reduction of superoxide and mitochondrial function

(2013) Laura L. Dugan et al.   JOURNAL OF CLINICAL INVESTIGATION

Obesity-Mediated Autophagy Insufficiency Exacerbates Proteinuria-induced Tubulointerstitial Lesions

(2013) K. Yamahara et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Metabolomics Reveals Signature of Mitochondrial Dysfunction in Diabetic Kidney Disease

(2013) K. Sharma et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Regulation of lipid accumulation by AMK-activated kinase in high fat diet–induced kidney injury

(2013) Anne-Emilie Declèves et al.   KIDNEY INTERNATIONAL

Autophagy Attenuates Diabetic Glomerular Damage through Protection of Hyperglycemia-Induced Podocyte Injury

(2013) Li Fang et al.   PLoS One

Effect of Chenodeoxycholic Acid on Fibrosis, Inflammation and Oxidative Stress in Kidney in High-Fructose-Fed Wistar Rats

(2012) Zhijuan Hu et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Fenofibrate, a PPARα agonist, has renoprotective effects in mice by enhancing renal lipolysis

(2011) Yuki Tanaka et al.   KIDNEY INTERNATIONAL

Oxidative and Nitrosative Stress and Progression of Diabetic Nephropathy in Type 2 Diabetes

(2010) Hideki Fujii et al.   AMERICAN JOURNAL OF NEPHROLOGY

Oleate and eicosapentaenoic acid attenuate palmitate-induced inflammation and apoptosis in renal proximal tubular cell

(2010) Mariko Soumura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Farnesoid X Receptor Activation Prevents the Development of Vascular Calcification in ApoE −/− Mice With Chronic Kidney Disease

(2010) Shinobu Miyazaki-Anzai et al.   CIRCULATION RESEARCH

Diabetic Nephropathy Is Accelerated by Farnesoid X Receptor Deficiency and Inhibited by Farnesoid X Receptor Activation in a Type 1 Diabetes Model

(2010) X. X. Wang et al.   DIABETES

Nebivolol Attenuates Redox-Sensitive Glomerular and Tubular Mediated Proteinuria in Obese Rats

(2010) Javad Habibi et al.   ENDOCRINOLOGY

Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites

(2010) Brent A. Neuschwander-Tetri   HEPATOLOGY

Trps1 Haploinsufficiency Promotes Renal Fibrosis by Increasing Arkadia Expression

(2010) Z. Gai et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Protein Quality Control in the Cytosol and the Endoplasmic Reticulum: Brothers in Arms

(2010) Alexander Buchberger et al.   MOLECULAR CELL

As a Matter of Fat

(2009) Rita T. Brookheart et al.   Cell Metabolism

FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats

(2009) Sabrina Cipriani et al.   JOURNAL OF LIPID RESEARCH

Association between obesity and kidney disease: A systematic review and meta-analysis

(2007) Y. Wang et al.   KIDNEY INTERNATIONAL